1.The clinical value of serum CA125 in diagnosis of endometriosis caused pelvic pain
Chinese Journal of Primary Medicine and Pharmacy 2013;20(9):1304-1306
Objective To study the correlation of serum CA125 level and differentiation of endometriosis (EMs) and pelvic pain due to Ems.Methods The clincal data of 305 EMs patients were retrospectively analyzed,and they were divided into I,Ⅱ,Ⅲ,Ⅳ four stage according to r-AFS.The relevance of preoperative serum CA125 and differentiation of Ems and pelvic pain were assessed and statistically analyzed.Results The serum CA125 level was higher in Ⅲ,Ⅳ stage (69.4 ± 5.7) U/ml,(171 ± 11.5) U/ml than that in Ⅰ,Ⅱ stage (14.8 ± 1.2) U/ml,(36.3 ±3.0) U/ml,there was statistically significant difference (P < 0.05).The positive rate of CA125 increased progressively (12.1%,21.5%,40.2%,63.9%),but the difference was not statistically significant(P > 0.05).The pain syndromes in the clinical features of differentiation of Ems had obvious difference (P < 0.05).Conclusion The serum CA125 detecting can be used in differentiation of Ems,and it has important value in diagnosis and prognosis of EMs.
2.Research Advances of Hypertensive Complication
Journal of Zhejiang Chinese Medical University 2006;0(02):-
[Objective]To provide reference for the clinical prevention and treatment of hypertension and its complication.[Methods]Summarize the hypertension and its complication,therapy of chemical and TCM drug,and pharmacological test,through analyzing the related literatures in CNKI,Chinese biomedical database (CBM),and wanfang and vip from 1989 to 2007.[Results]To study the key role of mechanism of hypertension and its complications on hypertension research.[Conclusion]The treatment of hypertension which can be caused by many factors and its complications should be"combination of disease and syndrome."
3.Thoughts and Realization of a General Drug Administrative System
China Pharmacy 1991;0(06):-
OBJECTIVE: To realize the general use of product managing software in management of drugs in modern hospital. METHOD: The softwares for import, sales and storage of pharmaceutical products in modern hospital were analyzed and compared. The type with best data transplant was found out and grafted upon the module relation. The network technology of programming tool VB was adopted to establish the sensitivity of the effective word section in the database , and the structure of the data was set up in an selective way in the procedure initializing window. RESULTS: The chaining of the system with many kinds of databases was completed. CONCLUSION: The modern programming technology combined with effective establishment of the database can be employed to transplant the complicated data, and therefore the medicine management software can be expected to be in general use.
4.Recent application of minimally invasive robotic cardiac surgery
International Journal of Surgery 2011;38(12):825-828
The minimally invasive approach is the direction of cardiac surgery.With the development of telemanipulation and computer technology,the minimally robotic surgery has become reality.As the one of the most minimally invasive cardiac surgery,the robotic surgical system provides cardiac surgeons with less invasive manner and dexterity manipulation.Robotic cardiac surgery is an evolutionary process and has resulted in a substantial increased attention to surgeons and patients.This review is to introduce the recent clinical application of robotic technology in cardiac surgery.
5.Oxaliplatin and teniposide inhibited proliferation and induced apoptosis of gastric cancer cell line BGC-823
Tumor 2010;(1):31-35
Objective:To investigate the effects of oxaliplatin (OXA) and teniposide (VM-26) on proliferation and apoptosis of gastric cancer cell line BGC-823.Methods:MTT assay was used to examine the inhibition rate of cell growth when cells were treated at various concentrations of OXA and VM-26 alone or in combination. The apoptosis was examined by flow cytometry (FCM). The protein expression of cell apoptosis associated proteins caspase-9 and livin were examined by immunocytochemistry. Results:OXA or VM-26 effectively inhibited the growth of BGC-823 gastric cancer cells in a concentration-dependent manner at certain range of concentrations. The inhibitory rate of combined treatment with OXA and VM-26 was significantly higher than that of OXA or VM-26 alone (P<0.05). The value of combination index (CI) was 0.46. The rate of apoptosis cells induced by 1.25 μg/mL OXA was 6.13%, 13.86% and 21.48% at 12, 24 and 48 h. The apoptosis rate induced by 0.625 μg/mL VM-26 was 4.60%, 10.72% and 17.07% for 12, 24 and 48 h. In combined treatment group the apoptosis rate was 11.73%, 24.14% and 44.75% at 12, 24 and 48 h, respectively. The difference was significant between combined treatment group and single drug treatment group (P<0.05). Immunnocytochemical analysis showed that the expression of caspase-9 protein was up-regulated after being exposed to OXA (1.250 μg/mL) or OXA plus VM-26 (0.750 μg/mL), while the expression rate of livin protein was down-regulated. There were significant differences among different treatment groups as well as between treatment groups and control group (P<0.05).Conclusion:OXA combined with VM-26 has synergistic effects in inhibiting the growth and inducing apoptosis of gastric cancer BGC-823 cells.
6.Content Determination of Gastrodine in Naomaito1g Oral Liquid with 2nd Derivative Spectrophotometry
Chinese Traditional Patent Medicine 1992;0(09):-
The 2nd derivative spectrophotometry was developed fo r the content determination of gastrodine in Naomaitong Oral Liquid. This methodis simple and rapid. Its' teproducibility is well.
7.THE PHAGOCYTOSIS OF TWO TYPES OF ALVEOLAR MACROPHAGES ON COAL DUST IN VITRO: IMAGE ANALYTICAL AND SCANNING ELECTRON MICROSCOPIC STUDIES
Acta Anatomica Sinica 1957;0(04):-
The phagocytic ability and fashion of two types of alveolar macrophages (AM) on coal dust were studied by differential interference contrast microscope, scanning electron microscope and image analyser. This study revealed the phagocytic ability of spherical AM on dust was higher than that of the flat AM. Both types of AM could extend long tenuous filopodia to the coal dusts around the cells. The coal dusts were attached to the cell surface and then were sunk into the macrophage. The amount of the phagocyted coal dusts per unit time were measured by image analytical method which is more exact than other methods. This paper provided not only a new approach for study phagocytosis of macrophage on inorganic dusts, but also some essential morphologic evidences for study of pneumoconiosis.
8.Comparison of different concentration mitomycin C in the treatment of recurrent pterygium
International Eye Science 2015;(2):359-360
AlM: To compare the clinical efficacy of treatment on recurrent pterygium using different concentration mitomycin C ( MMC) in the pterygium excision operation combined with the corneal limbal stem cell autografting ( CLSCA) .METHODS: Sixty patients ( 65 eyes ) with recurrent pterygium were randomly divided into three groups. All cases were accepted CLSCA, 21 patients (22 eyes) were given 0. 15g/L MMC during operation, 20 patients ( 22 eyes) were given 0. 25g/L MMC during operation, 19 patients ( 21 eyes ) were given 0. 4g/L MMC during operation. The patients were followed up for 6mo to 2a.RESULTS:The recurrent rates of the three groups were 9%, 5%, 5% respectively. There was no statistically significant differences (P>0. 05). The complication rates of the three groups were 5%, 36%, 33% respectively. There were statistically significant differences (P<0. 05). CONCLUSlON: The treatment to the recurrent pterygium using low concentration MMC has the similar recurrence rates, but the complication rate was lower, it is an ideal operation method, and it is worth popularization and application.
9.Research progress on detecting low molecular weight analytes based on surface plasmon resonance sensing technology
International Journal of Biomedical Engineering 2010;33(1):1-6
Surface plasmon resonance (SPR) sensing technology is a high-tech optical detection technolo-gy developed quickly in recent years, which combines biology, polymer chemistry and sensing technologies to form a rapid, sensitive, specific, portable and easy to operate detection technology. This paper outlines the mech-anism of SPR sensing technology for detection of low molecular weight analytes, the main application methods and research progress, discusses the advantages and shortages of the method, and foretastes the development prospect of this technology.
10.Treatment effects of docetaxe or irinotecan combined with cisplatin on patients with advanced non-small cell lung cancer
Cancer Research and Clinic 2010;22(9):598-600
Objective To observe and compare the recent objective response rate and adverse reaction of docetaxe and irinotecan combined with cisplatin in the treatment of advanced non-small cell lung cancer (NSCLC). Methods Sixty-five patients with advanced NSCLC were randomly divided into goup A consisted of 33 patients received docetaxe plus capecitabine and group B consisted of 32 patients received irinotecan plus capecitabine with a 21-day regimen. Two or more cycles of chemotherapy were completed in each group. Results Sixty-five patients were assessable for efficacy and toxicities. In group A, 2 patients achieved complete response, 13 patients partial response, overall response rate was 45.45 % and the median progression-free survival (PFS) was 10.1 months. In group B, 2 patients achieved complete response, 12 patients partial response, overall response rate was 43.75 %, and the median PFS was 10.2 months. The efficacy and PFS were not significantly different between the two groups(P >0.05). The most common adverse reactions were myelosuppression and gastrointestinal response in the two groups. The main adverse reactions is anemia in group A and diarrhoea in group B. Patients in group A experienced more anemia. On the contrary,the rate in group B was more increased. No chemotherapy-related death was observed. Conclusion The effects of docetaxe combined with cisplatin and irinotecan combined with cisplatin in the treatment of advanced NSCLC are comparable and equivalent, and the adverse reactions can be tolerated.