New investigations indicated that half of the people in the world had the risk of vitamin D deficiency.The main reasons for vitamin D deficiency was that people ignored the importance of using vitamin D supplement in special ages and seasons.Children were potentially at high risk for vitamin D deficiency.Vitamin D deficiency during childhood could cause rickets,growth retardation,skeletal deformities and might increase the risk of osteoporosis and hip fracture in later life.Vitamin D deficiency were also related with cancer,autoimmune disease,endocrine system disease,nervous system disease,hypertension and infection.

Anal Canal ; pathology ; surgery ; Humans ; Laparoscopy ; methods ; Rectal Neoplasms ; pathology ; surgery

Objective:To develop an HPLC method for the content determination of paeoniflorin, tetrahydropalmatine and osthole in Gujinwan capsules. Methods:The determination was performed on an Eclipse XDB-C18 column (250 mm × 4. 6 mm,5 μm) with the mobile phase consisting of 0. 1％ phosphoric acid (adjusting pH to 6. 6 with triethylamine)-acetonitrile with gradient elution. The flow rate was 1. 0 ml·min-1 . The column temperature was 30 ℃. The detection wavelengths were set at 230 nm and 280 nm. Re-sults:The calibration curves were found to be linear within the range of 9. 56-33. 65 μg· ml-1 for paeoniflorin(r=0. 9998), 3. 65-12. 86 μg· ml-1for tetrahydropalmatine(r=0. 9999) and 5. 81-20. 45 μg· ml-1for osthole(r=1. 0000). The average recovery of paeoniflorin, tetrahydropalmatine and osthole was 98. 8％(RSD=1. 1％), 98. 4％(RSD=0. 8％) and 99. 1％(RSD=1. 4％)(n=6),respectively. Conclusion:The method is simple, accurate and reproducible, which can be used for the quality control of Gujinwan capsules.

The pffect of 5 drugs on myocardial nutritional blood flow of micehave been determined with ~(86)Rb. It was shown that the root of xanthiumsibiricam, caesulpinia sepiaria and the branch of cinnamomum cassia couldincrease myocardial nutritional blood flow in mice The Pharmacologicalactions of these drugs have heen reviewed briefly.

Dimethyltrilobine iodide (DMT) 1.5 M-M increased the contractile force of isolated guinea pig left atria. This positive inotropic action could not be an-tagonized by either propranolol, cimetidine or diphen-hydramine. DMT 1.5 nM also increased the contractile force of isolated guinea pig left atria exposed to low concentration of calcium or to verapamil.

Thin basement membrane nephropathy(TBMN) is one of the most common disorders of the kidney,affecting at least 1% of the population.It seems to be a disease of the adult glomerular basement membrane(GBM) type Ⅳ collagen trimer ?3∶?4∶?5.Genetic evidence indicates that autosomal TBMN is caused by heterozygous mutations in either COL4A3 or COL4A4, whereas homozygous or combined heterozygous mutations in the same genes lead to autosomal recessive Alport syndrome.The author summarized the epidemiology,clinical features,renal biopsy,genetics,pathogenesis,diagnosis and therapy of TBMN.

Objective:To study the content of polysaccharide and its antitumor activity in the edible part and the disused part of asparagus. Methods:A orthogonal design of 4 factors and 3 levels was applied to optimize the solvent concentration, solid-liquid ratio, extraction duration and temperature that influencing the extraction efficiency. The difference in the polysaccharides content between the two parts was compared, and the difference in the antitumor activity against MCF-7 cells was observed with SPSS software. Results:The optimum extraction technology was used. The difference in the polysaccharide content between the edible part and disused part of asparagus was significant (P<0. 05). The antitumor activity of the two refined polysaccharides against MCF-7 cells was without nota-ble difference (P>0. 05). Conclusion:There is significant difference in the content of polysaccharide in the edible part and the dis-used part of asparagus, however, there is no significant difference in the antitumor activity in the two parts of asparagus.

Adult ; Drug Combinations ; Drugs, Chinese Herbal ; therapeutic use ; Fatty Liver ; drug therapy ; Female ; Humans ; Male ; Middle Aged ; Phytotherapy ; Powders

Monitoring,recording and treatment can be made to sleeping breath suspension patient using the present physiology recorder,oximeter and breath sensor,change-over interface,therapy device.When it lasts more than 10 seconds for patient's breath suspension,stimulator will be on automatically in order to revive the patient and off automatically after the patient's breath is recovered.