1.Color dopplar ultrasound examination of thromboangiitis obliterans lesions
Chinese Journal of Postgraduates of Medicine 2011;34(z2):1-2
Objective To study the ultrasonographic changes and blood flow characteristic ofthromboangiitis obliterans (TAO) by two-dimensional ultrasound and color Doppler imaging MethodForty-seven vessels of 40 patients with clinically suspected TAO vascular detected with two-dimensionalultrasound and color Doppler,and comparison with CT imagmg.Results Color Doppler imaging couldvisualize the arterial wall and blood flow echo filling case,and the spectrum showed the hemodynamicchanges.Conclusions Color Doppler is the first choice for the secondary check to the noninvasivethromboangiitis obliterans,close to the result by an angiography that is usually regarded as a sensitive,accurate and convenient diagnostic method.
3.Research progress in biomarkers of pulmonary fibrosis diseases
Ming CHEN ; Ming ZENG ; Xingxuan HE
Chinese Journal of Pharmacology and Toxicology 2017;31(2):187-194
Pulmonary fibrosis is a group of chronic lung diseases induced by various causes. Because of its complex etiology and pathogenesis,most of the pulmonary fibrosis diseases have no effective treatment currently and the quality of life and prognosis of patients are poor. Recent studies on biomarkers of susceptibility and effect associated with pulmonary fibrosis have made great progress, which is of great significance for screening and early diagnosis of the disease,and even for the evaluation of therapeutic efficacy and prognosis. This paper reviews some potential biomarkers of pulmonary fibrosis diseases,including the mucin 5B promoter variant and matrix metalloprotease-7 associated with idiopathic pulmonary fibrosis,heme oxygenase-1 and serum Se related to silicosis,Krebs von den Lungen-6,surfactant proteins-D and sphingolipids signaling associated with various pulmonary fibrosis, in order to provide new ideas for further research on the prevention and treatment of pulmonary fibrosis diseases.
6.Study of CT and Clinical Manifestations of Cardiac Carcinoma
Wen CHEN ; Jian WU ; Ming ZENG ; Yixiong ZENG
Journal of Practical Radiology 2001;0(07):-
Objective To evaluate the preoperative CT scanning in cardiac carcinoma.Methods 52 cases of cardiac carcinoma proved by operation and pathology were analysed.Results By CT scanning,the size of the tumor,it′s local extension and relation to the adjacent structures and lymph node metastases could be demonstrated.Conclusion CT scanning plays important role in the operability of the cardiac carcinoma and the planning of treatment.
8.A review of etiology and management of sialorrhea.
Yu ZHOU ; Xin ZENG ; Qian-ming CHEN
Chinese Journal of Stomatology 2007;42(2):126-128
Humans
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Sialorrhea
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etiology
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therapy
9.Role of sphingolipids signaling in pathogenesis of pulmonary fibrosis
Jiping YI ; Ming ZENG ; Xingxuan HE
Chinese Journal of Pharmacology and Toxicology 2016;(2):158-164
Pulmonary fibrosis is a group of chronic lung diseases caused by various factors and characterized by chronic inflammations,lung tissue structure damage,increase of pulmonary interstitial collagen and massive deposition of extracellular matrix (ECM). Because of its complicated etiology, there is no effective treatment currently. Recent studies showed that the activation of sphingolipids signaling and pulmonary fibrosis were closely related. This paper describes the composition and function of sphingolipids signaling pathway and its effect on fibrosis in order to provide new ideas about further study of the pathogenesis of pulmonary fibrosis and methods of prevention.
10.Serological changes for syphilis in infants born to treated syphilitic mothers
Lin PANG ; Huihui ZENG ; Ming HE
Chinese Journal of Perinatal Medicine 2010;13(4):282-285
Objective To explore the serological variations for syphilis in infants delivered by treated syphilitic mothers and its influencing factors. Methods Totally, 146 singleton gravidas, who had been treated for syphilis during pregrancy from January 2006 to January 2008 in our hospital, were chosen. Rapid plasma reagin(RPR) and treponema pallidum particle agglutination assay (TPPA) of these mothers before delivery and of the newborns within 3 d after delivery were tested and 92 of the 146 babies were followed up until the age of 24 months. Results (1) Among the 146 neonates, 104 (71.2%) were positive for both RPR and TPPA and 140 (95.9%) TPPA positive only. The RPR positive rate in neonates born to RPR+ + TPPA+ mothers were higher than those born to TPPA+ (only) mothers (81.4% vs 36.4%,χ2 = 25. 3, P<0. 01). 90.4% of the RPR+ neonates (94/104) showed lower or equivalent RPR titers compared to their mothers. (2) Among the 92 babies bein g followed up, the seroreversion of RPR were found in 98. 2%(n = 56) of the 57 babies, who were RPR+ +TPPA+ at delivery, at the 6 months and 100% (n=57) within 8 months, with the peak time within 2 months after birth (78. 9%, n = 45). While, 100% of the babies were found to be TPPA-within 24 mo with the peak time at 10~18 mo (64. 9%, n = 37). For those babies with TPPA+ at delivery, all turned to be TPPA- at 18 mo, with the peak time at 6 ~ 12 mo (57. 1%, n = 20). (3) The seroreversion time of babies with maternal RPR between 1:1~1:4 was later than those with maternal RPR (P<0.05). The seroreversion time of babies with maternal RPR titer of 1:4 was longer than those with maternal RPR titer of 1 > 1 [(2.5±0.8) mo vs (1. 2±0. 4) mo,P<0. 01]. However, the maternal RPR titer did not affect the TPPA reversion time (P > 0.05). The seroreversion time of RPR in infants with neonatal RPR titer of 1 : 4 was later than those with neonatal RPR titer of 1:1 [(3.7±0. 9) mo vs (2. 3±0. 6) mo,P<0. 01], and babies with RPR titer at 1 : 1 - 1 :4 showed longer duration than those with neonatal RPR- in TPPA seroreversion [(11. 2±2. 8) mo, (12.2±2.9) mo, and (11.0±2.2) mo vs ( 6. 9±2. 1) mo, P< 0.01, respectively]. Conclusions Most infants born to syphilitic mothers are serological positive for syphilis despite of standard maternal treatment during pregnancy. Infants, with higher maternal RPR titer during the pregnancy or at delivery, may persist to be serological positive for syphilis for a longer perieod, but all will turn to negative finally. Long term follow up is recommended for serological positive infants, and the diagnosis of congenital syphilis should be cautious.