A computer-based online search was conducted in PUMMED, English Medical Current Contents (EMCC), China Journal Full-text Database (CJFD), and Wanfang Database to summarize application and research progress of large-diameter femoral head hip prosthesis from January 1995 to January 2008. There were 62 literatures in total. Previous studies reported that when diameter of femoral head hip prosthesis was>32mm, joint worn out remarkably. During recent years, more and more basic and clinical researches demonstrate that diameter of femoral head is not correlated with wear rate; in particular, diameter of femoral head is not related to wear rate of artificial joint made by high cross linked polyethylene, metal, and ceramics. The superiority of large-diameter femoral head hip prosthesis has been paid more attention because of stability and activity. With the enlargement of diameter of femoral head, dislocated incidence decreases remarkably, and improvement of head-neck ratio increases the activity of prosthesis and reduces collision between two prostheses. Recently, large-diameter femoral head hip prosthesis has been widely applied for metal-on-mental hip joint, in particular, for hip resurfacing arthroplasty; in addition, large-diameter femoral head hip prosthesis plays a distinct role in joint replacement.

The factors impacting the pregnancy rate and the live birth rate mainly include ovary function disorder and low endometrial receptivity, which can cause the difficulty in embryo implantation, early miscarriage and pregnancy failure. In recent years, researchers of the traditional Chinese medicine (TCM) have made active efforts in assisting IVF-ET, so as to achieve a great advance in improving the ovary reaction, treating the ovarian hyperstimulation syndrome (OHSS), improving the follicle, embryo quality and endometrial receptivity and protecting the fetus, which had been summarized in this article.
Drugs, Chinese Herbal ; administration & dosage ; Embryo Transfer ; Female ; Fertilization in Vitro ; drug effects ; Humans ; Infertility, Female ; drug therapy ; therapy ; Pregnancy

Objective To explore the effect of valproate(VPA) on body mass index(BMI),leptin and serum lipids in children with epilepsy.Methods (Twenty-)four cases with epilepsy were selected.BMI and serum levels of leptin,total cholesterol(TC),(triacylgly)-cerol(TG),high density lipoprotein-cholesterin(HDL-C),low density hipoprotein-cholesterin(LDL-C) after treated with VPA for 3 months and 6 months were determined.Results The levels of BMI,leptin,TC,TG,LDL-C after treated 3 months were all significantly higher than those of initial(all P0.05).Those in treated 6 months were same as levels of treated 3 months.Only LDL-C level was lower than that of 3 months and same as level of before treatment.Conclusion VPA do have efficacy to cause obesity in children with epilepsy,and most of the cases occur in the first 3 months after VPA treatment.

Traumatic optic nerve injury ( TON) is caused by direct or indirect optic nerve trauma, which is one of a serious complication of craniocerebral trauma. lts prognosis poor and usually bring permanent vision damage. At present, optic nerve injury and regeneration is hot in neurobiology research. To build an ideal experimental animal model is extremely important in research and development in the treatment of optic nerve injury. ln this article, we review the methods of making rat models of traumatic optic neuropathy, clinical similarities, advantages and disadvantages of among these models, to provide reference for more experimental study.

Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Drug-Related Side Effects and Adverse Reactions ; epidemiology ; Female ; Humans ; Infant ; Male ; Middle Aged ; Pesticides ; poisoning ; Young Adult

Humans ; Isoniazid ; blood ; Spectrophotometry, Ultraviolet

Azabicyclo Compounds ; blood ; Humans ; Piperazines ; blood ; Spectrophotometry, Ultraviolet

Azabicyclo Compounds ; blood ; Chromatography, Gas ; Humans ; Piperazines ; blood ; Serum ; chemistry

Chromatography, Gas ; methods ; Humans ; Ibuprofen ; blood

Chromatography, Gas ; methods ; Ethylene Glycol ; blood ; Humans