Hemorrhage ; pathology ; Humans ; Thrombocytopenia ; pathology

Objective To investigate the distribution characteristics and drug resistance of pathogenic bacteria in ICU . Methods The bacteria identification and drug sensitive test were carried out on all pathogenic bacteria in ICU of our hospital from January 2013 to December 2013 .Results A total of 187 strains of pathogenic bacteria were separated ,among them 37 strains (19 .79% ) were Gram‐positive bacteria ,which was dominated by staphylococcus aureus ,with drug resistance rate to vancomycin , teicoplanin and linezolid of 0 .00% ;135 strains were Gram‐negative bacteria (72 .19% ) ,which was dominated by pseudomonas aeruginosa ,acinetobacter baumannii ,klebsiella pneumoniae and escherichia coli ,the drug resistant rate of acinetobacter baumannii to cefoperazone/sulbactam and minocycline was lower (43 .59% ,46 .15% ,which of pseudomonas aeruginosa to amikacin ,cefotaxime , cefoperazone/sulbactam were 27 .91% ,32 .56% and 30 .23% ,respectively ;15 strains(8 .02% ) of fungi were isolated ,which were mainly candida albicans and candida tropicalis .Conclusion Regular detection of distribution types and drug resistance change can provide the basis for climical rational use of antibacterial drugs .

Lyme disease is continuing worldwide spread and its prevalence still presents raising tendency.The causative agent is Borrelia Burgdorferi(Bb) and the special biological intermedia is ixodid ticks(Ixodes scaputaris).The current study on the genetic strain of Bb and the interpretation of laboratory diagnosis(microscopic,immunologic and biomolecular test)results as well as the preparation of vaccine for the disease are made in this review.

Throughout history,there are less female physicians in the society of ancient China.Why? How to interpret this phenomenon? However,the research concerned in this field is rather limited.Thus the purpose of this research was aimed at paraphrasing the doubtful phenomenon above.Based upon this idea,we had originally selected some representative female physicians to make analyses and investigation.The results indicated that the tradition concept-which man is dominating in the society may be the main reason to account for this social phenomenon.It was related as well to the education,the social consensus,the value judgment and the vocationally characteristic towards women.These may lead to numerous barriers for women to become real doctors.It seems that the finding in this research could provide more background information for the occupation of female.It may also stimulate the women to be more independent in the modern China.

AlM: To compare the clinical efficacy of treatment on recurrent pterygium using different concentration mitomycin C ( MMC) in the pterygium excision operation combined with the corneal limbal stem cell autografting ( CLSCA) .METHODS: Sixty patients ( 65 eyes ) with recurrent pterygium were randomly divided into three groups. All cases were accepted CLSCA, 21 patients (22 eyes) were given 0. 15g/L MMC during operation, 20 patients ( 22 eyes) were given 0. 25g/L MMC during operation, 19 patients ( 21 eyes ) were given 0. 4g/L MMC during operation. The patients were followed up for 6mo to 2a.RESULTS:The recurrent rates of the three groups were 9%, 5%, 5% respectively. There was no statistically significant differences (P>0. 05). The complication rates of the three groups were 5%, 36%, 33% respectively. There were statistically significant differences (P<0. 05). CONCLUSlON: The treatment to the recurrent pterygium using low concentration MMC has the similar recurrence rates, but the complication rate was lower, it is an ideal operation method, and it is worth popularization and application.

Objective To investigate the clinical diagnosis and treatment of pneumocystis carinii pneumonia(PCP) after kidney transplantation. Methods Eight patients who developed PCP between 90 days and 140 days following renal transplantation were enrolled in this study.All of them were male with a mean age of 28 years.The clinical manifestations,accessory examinations and treatment were retrospectively analyzed. Results All the 8 patients fully recovered.With early diagnosis and administration of compound sulfamethoxazole(SMZ),clinical symptoms of 6 patients were rapidly controlled within 5 to 7 days.Because of delayed diagnosis and treatment,the conditions of the other 2 cases were more severe and were controlled within 25 days and 46 days separately. Conclusions Application of percutaneous pneumocentesis biopsy can be useful for correct diagnosis in early stage of PCP and has high positive rate of the pathogen. Most PCP patients can be cured with early use of SMZ.Types and doses of immunosuppressor should be adjusted properly.

Objective To evaluate the efficacy and safety of two-dose basiliximab vs two-dose daclizumab for prevention of acute rejection in renal transplantation. Methods A total of 58 renal transplant recipients were randomized into 2 groups:basiliximab group ( n =30) and daclizumab group ( n =28).All the cases received the triple therapy of cyclosporine,mycophenolate mofetil and prednisolone (CsA+MMF+Pred).The 3 medications were administered as follows.For CsA,initial dose of 6 mg/kg per day was downtitrated to 4～5 mg/kg per day at 3 months,then to 3～4 mg/kg per day at 6 months.For MMF,initial dose of 0.5 g,3 times per day was downtitrated to 0.5 g,twice per day at 1 month.For Pred,initial dose of 30 mg per day was downtitrated to 20 mg per day at 3 weeks,then to 10～15 mg per day at 6 months.Basiliximab group received two-dose basiliximab (20 mg intravenous infusion) 2 hours before operation and 4 days after transplantation.Daclizumab group received two-dose daclizumab (50 mg) 1 day before operation and 14 days after transplantation.Postoperatively,acute rejection was monitored for 6 months,and adverse events and person/allograft survival were observed for 6～12 months.CD25 + cell count was tested using Beckman Coulter flow cytometer before operation and postoperatively once a week for 2 months. Results During 6-month follow-up, the number of acute rejection episodes were 5 in daclizumab group and none in basiliximab group ( P

Objective:To investigate the effect of edaravone injection on the neuron-specific enolase(NSE) concentration in serum from patients with acute cerebral infarction.Methods:The NSE concentrations in serum from 35 patients were measured by an ELISA method.Neurological deficit was scored for clinical effect assessment.Results:Serum NSE levels and neurological deficit scores in edaravone treating group significantly decreased at d 3 compared with those in routine therapy group((P

0.05).[Conclusion]1.It showes a higher stress dodge in the calcar femorale after using various kinds of prosthesis implantation.After using CFR/PSF of lower elastic modulus as handle,the stress dodge rate is lower in femur,but the interface stress is higher,and this is the main factor and reason for the prosthesis loosening.2.The stress force rule meets the design principle that the stress force decreases gradually in the bone interface from proximal to distal.The stress value in different combination of same prosthesis handle has no significant difference,that showes mechanical factor is not the main standard for selecting prosthesis combination.

[Objective] To study the clinical results of the total hip replacement with different materials prosthesis.[Methods]Eighty-five patients(nighty-two hips)undergoing total hip replacement were enrolled in this study.Through X-ray examination,the stress force of different material prosthesis on the proxmial femur and periaccetabular bone was observed.[Results]There were no clinical signs of the loose or bone absorption around the prostheses in all patients.Debris reaction was found in the metal-polyethylene group and ceramic-polyethylene group,not found in the metal-metal group and ceramic-ceramic group.[Conclusion]The stress force between different material prostheses and bone interface was not significantly different.Bone osteolysis doue to wear of polyethylene prosthesis is the key factor for the long-term outcomes of the total hip replacement.In addition,it is correlated with prosthesis manufacture,bone quanlity and surgical technique.