Objective To explore the cause of repeated offline of files in the database of No.1 Military Project and find the method to solve the problem. Methods The abnormal offline of files in database is not by chance,and its document in oracle is not very clear. Using the knowledge from internet,the fault was repeatedly simulated on test machine and the source of the fault was found. Results Solving plans and countermeasures were put forward. Conclusion The database of the No.1 Military Medical Project is the core of military hospital work,so its importance is self-evident. The technical support of No. 1 Military Project is strengthened,the right maintenance direction of the database is pointed out as well as the right solution to deal with the problem.

Chickenpox may lead to several neurological complications. Optic neuritis is one of the complications which has rarely been described, especially in immunocompetent individuals. We report a case of an 11-year-old immunocompetent girl who presented with sudden onset bilateral vision loss three weeks after varicella eruption. Ophthalmic examination revealed bilateral optic disc edema. Diagnosis of bilateral optic neuritis secondary to varicella was established based upon the preceding medical history, supported with clinical and radiological fndings.

No abstract available.
Exercise ; Health Behavior ; Health Promotion ; Humans ; *Motor Activity

In previous case report entitled "Multidetector CT findings of a congenital coronary sinus anomaly: a report of two cases" by Chou et al. (Korean J Radiol 2008;9:S1-S6), there were mistakes. "The Figure 1A and 1B are the MDCT findings of normal coronary sinus of a normal individual." "The Figure 1C to 1E are the MDCT findings of congenital coronary sinus anomaly in 60-year-old woman with Ebstein's anomaly." "The Figure 2J and 2K are illustration of atresia of the right atrial ostium of the coronary sinus with/without PLSVC"

Given the myriad of choices available on the market, selecting the appropriate wound dressing remains a challenge for most healthcare workers. It is important to exercise discretion and adopt a systematic approach in dressing selection following wound assessment, as this will directly impact on rates of wound healing, which in turns affects the patient’s quality of life and overall healthcare costs. This paper provides an overview of the common types of wound dressings in use currently and gives a brief synopsis of some of the latest advances in wound care technology and their applications in management of complex wounds. The consensus to date is for the use of hydrogels in the debridement stage, foams and low-adherence dressings in the granulation stage and hydrocolloids and low-adherence dressings for the epithelialization stage. Additional studies and research need to be undertaken to further evaluate the application of advanced wound technology in clinical practice.

Aged ; Burkitt Lymphoma ; complications ; pathology ; Humans ; Intestinal Perforation ; etiology ; Jejunal Diseases ; etiology ; Jejunal Neoplasms ; complications ; pathology ; Male

INTRODUCTIONBuprenorphine is an opioid partial agonist approved in several countries for the treatment of opioid dependence. It was approved in Singapore in 2002 for this indication, and is more widely available in the primary care setting and can be prescribed by all licensed physicians who have undergone designated training. There is limited literature addressing the risk of its illicit abuse via intravenous self-administration.

CLINICAL PICTUREWe report 2 such cases of the abuse of prescription buprenorphine in the psychiatric consultation-liaison service of a general teaching hospital, the treatment approaches and outcomes.

CONCLUSIONWe also briefly review the indications, uses and abuses of buprenorphine in Singapore, and as reported in other countries, and the roles of primary care physicians, in order to stimulate greater awareness and understanding among specialists and general practitioners, who would encounter these patients in various settings.

Adult ; Buprenorphine ; therapeutic use ; Drug and Narcotic Control ; Female ; Humans ; Male ; Narcotic Antagonists ; therapeutic use ; Opioid-Related Disorders ; rehabilitation ; Pregnancy ; Pregnancy Complications ; diagnosis ; therapy ; Primary Health Care ; Role ; Substance Abuse, Intravenous ; diagnosis ; prevention & control ; therapy

Caffeine had been shown to have an ergogenic effect on trained individuals; however, studies investigating the physiological effects of caffeine on the sedentary population are limited. The aim of this study was to examine the effect of caffeine on oxygen consumption and rating of perceived exertion during moderate intensity exercise among sedentary young adult females. Subjects comprised 16 female undergraduates aged between 22 to 24 years studying at Universiti Kebangsaan Malaysia. Eligibility criteria were based on low physical activity level and daily caffeine intake of less than 50 mg a day, which was screened using the International Physical Activity Questionnaire (short version) and caffeine consumption questionnaire, respectively. The design of this study is single-blind, crossover, placebo-controlled with all subjects serving as their own controls. Subjects were required to report to the physical activity laboratory for two experimental sessions after either ingesting placebo or caffeine capsule with an interval of 3 days between these two experimental sessions. Sixty minutes after ingesting placebo capsule (Glucolin, glucose) or 100 mg caffeine (Pro-plus, United Kingdom), subjects were required to run on a treadmill for 30 minutes at a standardized power output equivalent to 60% of maximal heart rate. Oxygen consumption, heart rate, and rating of perceived exertion were recorded at 20th, 25th and 30th minutes, while blood pressure was recorded immediately after subjects completed their 30 minutes run. Mean body fat percentage was 28.4 ± 5.4. Differences were recorded after every subject completed both the placebo and caffeine experiments. Paired t-tests showed no significant difference between placebo vs caffeine trials for oxygen consumption (13.99 ± 2.47 vs 14.49 ± 1.73, p = 0.440), rating of perceived exertion (12.3 ± 2.5 vs 12.3 ± 2.1, p = 1.000), systolic blood pressure (113 ± 10 vs 117 ± 11, p = 0.129), diastolic blood pressure (67 ± 8 vs 69 ± 10, p = 0.408) and heart rate (127.3 ± 11.0 vs 127.1 ± 11.6, p = 0.912). There was strong significant negative correlation between body fat percentage and oxygen consumption (r = –0.568, p < 0.05) and strong significant positive correlation between body fat percentage and rating of perceived exertion (r = 0.515, p < 0.05). The non-significance in the results obtained could be due to the small effect size of the study (d = 0.24). Hence, future studies with a larger number of participants should be carried out to examine the effects of caffeine during exercise in a sedentary population

Aims: Bacteria on chicken egg surfaces can be potential sources of food borne diseases. The aim of this study was to determine the prevalence of E. coli, Salmonella and enterococci on the surface of conventional broiler eggs, “Kampung” chicken eggs and carrying trays and to determine the antimicrobial resistant profile of these isolates. Methodology and results: Conventional broiler eggs, “Kampung” chicken eggs and carrying trays were sampled randomly from nine wet markets in Selangor, Malaysia. The surface of the eggs and carrying trays were swabbed and E. coli, Salmonella and enterococci were isolated using selective agars. Antimicrobial susceptibility testing (AST) was performed on the isolates against different antimicrobials via disk diffusion test. A large proportion of E. coli isolates (>50% of isolates from conventional broiler eggs and “Kampung” chicken eggs) was resistant to chloramphenicol and tetracycline whereas enterococci (>60% of isolates from conventional broiler eggs and “Kampung” chicken eggs) isolates were resistant to tetracycline and erythromycin. Salmonella isolates were found to be susceptible to all of the antimicrobials tested except for tetracycline. There was also presence of isolates showing multiple resistances in this study. E. coli isolates (8.8%) from the surface of “Kampung” chicken eggs were resistant against 10 different antimicrobials whereas 17.8% of the enterococci isolates from the surface of “Kampung” chicken eggs were resistant to 11 different antimicrobials. Conclusion, significance and impact of study: The presence of multiple-antimicrobial resistant bacteria especially on the surface of “Kampung” chicken eggs that are ready to be sold to consumers is a serious concern. However, further study has to be conducted to determine the ultimate source of the bacterial contamination before specific food safety measures can be introduced.
Drug Resistance, Microbial ; Salmonella

The treatment of refractory Helicobacter pylori remains challenging in clinical practice. Factors that should be considered in the treatment of refractory H. pylori infection include treatment length, dosage of antibiotics and proton pump inhibitors (PPIs), number of drugs, and the selection of appropriate antibiotics. Extending the treatment length of triple therapy and non-bismuth quadruple therapy to 14 days may increase the eradication rate compared with a shorter period (7 or 10 days). The use of a higher dose of PPIs or vonoprazan may also increase the efficacy of triple therapy. Four-drug therapy, including bismuth or non-bismuth quadruple therapies, usually achieve higher eradication rates than triple therapy. The addition of bismuth or metronidazole to levofloxacin-amoxicillin-PPI therapy may also increase the eradication rate. Therefore, fourdrug therapies containing a higher dose of PPIs for 14 days are recommended in the third-line treatment setting for refractory H. pylori infection. The selection of appropriate antibiotics may be guided by susceptibility testing or empirically by medication history. Tailored therapy guided by susceptibility testing or genotypic resistance is recommended whenever possible. However, properly designed empirical therapy based on prior medication history (i.e., avoid the reuse of clarithromycin or levofloxacin empirically) is an acceptable alternative to tailored therapy after considering accessibility, cost, and the preference of the patient.