1.Analysis of Causes of Postoperative Acute Kidney Injury in Patients with Gastrointestinal Surgery
Danqing BI ; Zhu ZHOU ; Danyan BI ; Huayou LUO ; Ming ZHONG
Journal of Kunming Medical University 2013;(11):84-86
Objective To analyze the risk factors of acute kidney injury (AKI) in the patients undergoing gastrointestinal surgical procedures.Methods We retrospectively analyzed all gastrointestinal surgical patients nearly 2 years who were in the first affiliated hospital of Kunming Medical University and the first people's hospital of Yunnan province.Results The incidence of AKI was 2.1%.Univariate analysis and multivariate analysis indicated that: age>65 years, emergency operation and serious infection were significantly related with the incidence of AKI.Conclusion AKI is a common complication after gastrointestinal surgical procedures.This study showed that age>65 years, emergency operation, serious infection were risk factors most likely associated with postoperative AKI development.
5.The Prevention and Therapy of Postoperative Acute Kidney Injury after Gastrointestinal Surgery
Danqin BI ; Danyan BI ; Ming WENG ; Cheng TANG ; Qiuhong FU ; Mingfen HU ; Ming ZHOUN
Journal of Kunming Medical University 2014;(2):112-114
Objective To explore the prevention and treatment of acute kidney injury (AKI) after gastrointestinal surgical procedures.Method We retrospectively analyzed the data of patients underwent gastrointestinal surgery in recent 2 years in the First Affiliated Hospital of Kunming Medical University and the First People's Hospital of Yunnan Province. Result The incidence of AK1 was 2.1%. Elderly patients with basic diseases had poorer prognosis than non-elderly patients. Conclusion In the patients after gastrointestinal Surgery, early rehydration, diuresis, ant-infection and preventive hemodialysis can achieve the goal of prevention and treatment of acute kidney injury in early stage.
6. Therapeutic effects and mechanisms of total flavonoids of Chrysanthemum indicum on liver fibrosis in rats
Chinese Pharmaceutical Journal 2014;49(5):367-370
OBJECTIVE: To observe therapeutic effects and mechanisms of total flavonoids of Flos Chrysanthemum indicum (TFC) on liver fibrosis in rats. METHOD: The model of rat liver fibrosis was adopted which was induced by CCl4 injection. The effects of FFC were observed on the levels of serum ALT, AST, HA, LN, PC III and C IV in rats with liver fibrosis, and on liver histopathological 'hanges as well as collagen hyperplasia formation in liver tissue. The gene expression of TGF-β1 was detected by RT-PCR. RESULTS: Compared with the model group, TFC treatment significantly reduced ALT, AST, HA, LN, PC III and CIV content in serum, liver listology in the TFC treated rats was also improved. Moreover TFC could decrease the expression of TGF-beta;1. CONCLUSION: TFC Has a significant curative effect on the liver fibrosis rats, its mechanism probably be related to decrease the expression of TGF-beta;1.
7.Clinical Features of Cerebral Infarction with or without Diabetes Mellitus
Ming ZHANG ; Jinsheng ZHANG ; Jiajing BI ; Zhengzheng HAN ; Yongxi HUANG
Chinese Journal of Rehabilitation Theory and Practice 2011;17(9):861-862
Objective To investigate the clinical features of cerebral infarction complicated with diabetes mellitus (DCI) compared withthose without diabetes mellitus (NCI). Methods 80 DCI and 86 NCI hospitalized patients were reviewed with their serumal glucose, lipid,uric acid, hemorheology and carotid ultrasound. Results The total cholesterol, low density lipoprotein and uric acid were significantly higherin DCI group than in NCI group (P<0.05), while high density lipoprotein was significantly lower (P<0.05). There were significant differencesbetween these two groups in Hemorheological indicators except hematokrit (P<0.01). The carotid intima media thickness (IMT) wassignificantly higher in the DCI group than in the NCI group (P<0.05). Conclusion DCI patients suffered in more serious lipid, uric acid,hemorheological disorder, and IMT compared with NCI.
8.A 4-year follow-up of functional rehabilitation in a patient with allografted forearms
Zheng-Gang BI ; Ming SHAO ; Qing-Yang GUO ;
Chinese Journal of Orthopaedic Trauma 2004;0(12):-
Objective To report the functional reconstruction and rehabilitation for a patient who under- went allograft for both of his forearms and hands.Methods One male patient underwent allograft for both of his forearms and hands in October 2002 in our department to reconstruct his hand functions.The allografted hands were intervened with an integrated rehabilitation program,which involved administration of immunosuppressants,post- operative monitoring,postoperative functional training,massage,physiotherapy,orthosis,performance training, sensation training,secondary operation and mental rehabilitation.The patient was followed up for 4 years.Results The forearms and hands of the patient were in good shape and regained nearly normal sensation.The distance of two-point-discrimination was 2.5 cm to 4.0cm.The TAM (total active motion) of fingers was fine.The patient could look after himself well and were healthy in psychology.Conclusion An integrated rehabilitation program can yield satisfactory results in the management of allografted forearms and hands.
9.Clinical efficacy comparison of moxibustion with different doses for knee osteoarthritis
Yi-Wen WU ; Ming DAI ; Bi-Song CHEN ; Jing CHEN
Journal of Acupuncture and Tuina Science 2020;18(5):390-395
Objective: To compare the efficacy of moxibustion with different doses for knee osteoarthritis (KOA), and explore the correlation between moxibustion dose and clinical efficacy. Methods: Sixty-eight patients with KOA who met the inclusion criteria were randomly divided into a 20-minute moxibustion group and a 40-minute moxibustion group by the random number table method, with 34 cases in each group. Dubi (ST 35), Neixiyan (EX-LE 4) and Heding (EX-LE 2) were used for moxibustion in the two groups. Each treatment lasted 20 min or 40 min for each point in the 20-minute moxibustion group and 40-minute moxibustion group, separately; the treatment was given 3 times a week and lasted for 4 weeks. The visual analog scale (VAS), Western Ontario and McMaster University osteoarthritis index (WOMAC) and traditional Chinese medicine (TCM) symptom scores were evaluated before and after treatment to compare the efficacy between different moxibustion doses for KOA. Results: After treatment, the total effective rate was 87.5% in the 40-minute moxibustion group, versus 70.0% in the 20-minute moxibustion group, and the difference in the total effective rate between the two groups was statistically significant (P<0.05). After treatment, the VAS scores, the total WOMAC scores and the component scores of pain, stiffness and dysfunction, and the TCM symptom scores in both groups all changed significantly when compared with those before treatment (all P<0.05). After treatment, the between-group differences in the VAS score, the total WOMAC score and the component scores of pain and dysfunction, and the TCM symptom score were statistically significant (all P<0.05), while the difference in the stiffness score in WOMAC showed no statistical significance (P>0.05). Conclusion: Either 20-minute moxibustion or 40-minute moxibustion can relieve pain, improve stiffness, dysfunction, and TCM symptoms for KOA; and 40-minute moxibustion is better in relieving pain, improving dysfunction and TCM symptoms.
10.Effects of stress and ovariectomy on behavior activity in mice and intervention of TCM complex Ⅰ
Jianying HUANG ; Xiaoyuan LIAN ; Qi CHEN ; Ming BI ;
Chinese Journal of Clinical Pharmacology and Therapeutics 2000;0(01):-
AIM : To observe the effect of stress and ovariectomy on behavior activity in mice and the prevention and therapy of the TCM complexⅠcomposed of spine date seed and common anemarrhena rhizome. METHODS : The effect of stress and ovariectomy were investigated on bedtime, survival time under hypoxia, climbing time on the string and number of times of the activity in mice, and the prevention and therapy of TCM the complexⅠwere observed. RESULTS : The effect of stress, ovariectomy, stress and ovariectomy were different on bedtime, survival time under hypoxia and climbing time on the string and the number of times of the activity in mice. The effect of stress and ovariectomy on previous parameters was stronger than that of stress or ovariectomy lonely in mice. The stress and ovariectomy resulted in sleep impairment, the decreasing of the survival time under hypoxia and climbing time on the string, and the increasing of the number of times of the activity in mice. CONCLUSION : The TCM complex I can alleviate the high sensitivity to the environment in mice with ovariectomy and stress, which is similar to the mechanism of human climacteric syndrome.