Venous thromboembolism, which is a common thrombotic disease, is prone to become a fatal pulmonary embolism due to the lack of existing treatments.Although the anticoagulant drugs are widely used, the disease relapses easily.In recent years, there are much progress in the formation of venous thrombosis and diagnosis, and antiplatelet agents may play a certain role in the prevention of venous thrombosis.These new developments provide a new train of thought that platelets play as a breakthrough to find more effective treatments.This article summarizes the progress in the diagnosis of venous thrombosis on platelets in recent years, which discusses whether antiplatelet strategies could be applied in venous thrombosis so as to provide reference for further research.

To investigate the effect of the case-centered teaching method in biochemistry teaching. 47 students were divided into two groups :the study group and the control group.The casecentered teaching method was used in the studying group.The control group was taught by traditional method.The final examination showed that the results of the studying group were better than the control group.

we have designed a program-controlled high-fi amplifier for EMG.Its gain can be controlled by computer.The program-contralled circuit is implemented with numerical control resistor.The amplifier can be used in automatically measuring EMG signals over 100?v.The circuit is characterized by easy de- sign,simple programing and convenient control.

The author reviewed some researches on teacher's work related stress in China and abroad. The present researches mainly focus on the sources of stress in teachers' work life. Some practices of work related stress in USA and Chinese special education field were discussed in the article. In the end, the author took a perspective on future research of teacher's work related stress in Chinese special education field.

Objective To investigate the percentage of CD4 + C125 +Tregs in peripheral blood of patients with sepsis and its effect on cell immunity so as to unravel the effect of immunomodulatory therapy on it. Method Fourty patients with sepsis in ICU were randomly (random number) divided into experimental group and control group . The patients of experimental group were treated with Ulinastatin and immunoregulation agent (Thymosin αl) as well. The blood specimens were collected just before treatment, 3 days and 8 days after treatment. The percentages of CD4 + CD25 + Tregs and lymphocyte subsets were detected by using FCM (flow cytometry), and TNF-α, IL-6 and IL-10 assayed by using ELISA, and APACHE Ⅱ scores were calculated. Results Before treatment, the percentage of CD4 + CD25 + Tregs increased, and the number of lymphocytes and the percentage of T lymphocytes decreased, especially the CD4 + T lymphocytes and CD4+/CD8+ decreased more markedly, and the levels of IL-6 and TNF-α increased. After treatment,the percentage of CD4+ CD25 + Tregs was decreased, the number of lymphocytes and CD4 +/CD8 + increased, and the levels of APACHE Ⅱ score, IL-6 and TNF-α decreased especially in the experimental group decreased more significantly (P ＜ 0. 05). Conclusions The percentage of CD4 + CD25+ Tregs in peripheral blood can reflect the immune status of patients with sepsis and become a novel indicator to estimate the progress of sepsis, and the immunity and prognosis of patients. Treating the patients with Thymosin αl and Ulinastatin can raise their immunity, decrease the levels of IL-6, TNF-α and APACHE Ⅱ score and improve their prognosis.

Disasters ; Emergency Medical Services ; Humans ; Wounds and Injuries ; therapy

Objective To evaluate the intraluminal manometry of the colon and X ray examination of colon transport in the diagnosis of slow transport constipation (STC).[WT5”HZ] Methods [WT5”BZ] 46 patients and 25 healthy controls underwent X ray examination of colon transport function, and colonic intraluminal manometry. 29 patients received colectomy including total in 15, partial in 12, and ileo sigmoidocolostomy in 2. [WT5”HZ] Results [WT5”BZ] It was found that the marker of transport function test within the colon was held for much longer time than normal controls and the colonic intraluminal pressure was much lower in patients than in controls.[WT5”HZ]Conclusion [WT5”BZ] Intraluminal manometry of the colon and X ray examination of colonic transport function test help in establishing the diagnosis of STC. Total or partial colectomy effected a cure for STC.

Objective To evaluate the surgical results of off-pump for plication for left ventricular aneurysm. Methods The study included 34 patients with left ventricular aneurysm,who underwent left ventricular aneurysmecto- my and plicatien on pump in group Ⅰ(17 cases)and simply aneurysm plicatien off pump in group Ⅱ(17 cases).All patients except two in group I underwent coronary artery bypass grafting simultaneously.Results There was one early death in group Ⅱ because of refractory ventricular arrhythmia.The complication included atrial fibrillation,ventricular arrhythmias,heart failure and delayed healing of wound.The aneurysm in group Ⅰ[(45?15)%of the ventricle]is larger than in groupⅡ[(29?12)%of the ventricle,P

Objective To investigate the technical charactenstics ot SYSMEX XS1000i 5-part differential automated hematological analyzer and its clinical applications.Methods 209 samples were analyzed with the analyzer of XS1000i and compared to the results from Beckman-Coulter LH750 analyzer.The main parameters from XS1000i,such as precision within-run,day to day precision and carryover contamination rates etc,were recorded respectively in 509 samples to compare the difference between the instrumental and optical examination.Results All variation coefficients of precision from XSI000i were within the manufacturer.The carryover contamination rates of WBC,RBC,Hb,HCT and PLT were 0.19%,0.93%,0,-0.88%,-0.76%,respectively.The parameters of XS1000i were correlated with the results of LH750 except basophil granulocyte.The correlation coefficients of WBC,RBC, HGB and PLT were 0.994 5,0.996 8,0.997 0 and 0.974 6 ,respectively.The sensitivity of warning flags in immature leukocytes was 100% and the specificity was 69.7%,the sensitivity of warning flags in atypical lymphocyte was 100% and the specificity was 66.7%.Especially in 3 leukocytopenia that was induced by chemotherapy in patients with leukemia who had only few immature cells existed in the peripheral blood,the parameters of XS1000i were positive,and correlated with the results of detection of minimal residual disease with flow cytometry.Conclusions The warning system of XSIO00i provides more valuable information for manual microscopic examination.If it is combined with flow cytometry,the advantages in detection of residual leukemic cell will be fully displayed.

Objective To study the influence of cognitive behavioral intervention on the quality of marriage and family function in patients with depression. Methods 146 hospitalized patients with depression were divided into study group and control group according to the set sequence. The study group were given cognitive behavioral intervention and the control group were given routine nursing.All patients were assessed by Hamilton depression scale (HAMD), Hamilton anxiety scale (HAMA), family functioning (FAD), marriage quality questionnaire (ENRICH) to evaluate the depression and family function. Results The difference in ENRICH total score, marital satisfaction, conflict resolution, children and marriage, leisure activities and the relationship with family and friends,FAD total score, problem solving, emotional response was statistically significant between before and after the intervention of the study group ( <0.05) . In the 6th weeks, the difference in ENRICH total score, marital satisfaction, conflict resolution methods, children and marriage,leisure activities and the relationship with family and friends, FAD total score, problem solving,emotional response was statistically significant between the two groups ( <0.05);The difference in HAMD,HAMA score was statistically significant between the 0th and 6 th weeks of the two groups ( <0.05) . There was a negative correlation between HAMA and conflict resolution factor (=-0.48, <0.05) . There was a positive correlation between FAD and the HAMD total score (=0.43,<0.05) . There was a negative correlation between ENRICH and HAMD total scores (r=-0.46, <0.05) .Conclusion The cognitive behavioral intervention can improve the family function and the quality of marriage in patients with depression.