1.Studies on intrinsic inhibitor activity in seed of dried root of Saposhnikovia divaricata
Chinese Traditional and Herbal Drugs 1994;0(04):-
Object To investigate the reason of the low germination and sprout rates by studying on inhibitory activities of the crude extracts of the seed of the dried root of Saposhnikovia divaricata (Turcz.) Schischk (DRSD) on Brassica, wheat and the seed of DRSD. Methods The ether extract and residue of the crude extract were prepared and treated by paper chromatography. The inhibitory activities of different fractions with different Rf value were determined. Effect of steeping the seed in warm water at 41 ℃ and 45 ℃ for different periods of time was also studied, respectively. Results There are intrinsic inhibitor in the seed of DRSD with strong activity. The portion of its ether extract with Rf 0.6 showed the strongest inhibitory activity for the germination of Brassica seed. The crude extract of the seed of DRSD also has the stronger inhibitory activity to the germination and growth of tender root of S. divaricata and has the same effect on aerial part of wheat sprouts. Steeping with warm water and solvent can remove most of the intrinsic inhibitor. Conclusion Intrinsic inhibitor in the seed of DRSD is the main factor that results in the low germination and sprouting slowly after seeding.
2.No shelter growing technique for Radix Gentianae seedling
Chinese Traditional and Herbal Drugs 1994;0(08):-
Object To provide an economical and practical technique for planting of Radix Gentianae in large scale Methods Indoor artificial pregermination, insemination in carboxymethyl cellulose suspension, irrigation with micro sprayer and no shelter growing technique of seedling Results The seedling cost is 60% lower than that of conventional technique In each square meter 3 000 seedlings were grown Conclusion This technique can be widely applied.
3.A Scanning Electron Microscopic Study of the Air-way and Lungs of Normal and Blast Injured Rats
Journal of Third Military Medical University 1988;0(06):-
10 adult female rats were used to study blast injuries of the air-way and lung. The conclusions are as follows. 1. There was significant difference in arterial blood gas analysis between the normal control and injury group. 2. The une-venness in the lung damage, bleeding, tear of the alveolar septa induced by the air shock wave was predominant, by scanning electron microscopy (SEM) as well as by the light microscopy (LM) . The bleeding may be due to the capillary rupture of alveolar septa. The' rope-like' structures seen might represent the fibre component in the septa which had more resistance to the local force and remained after the other components were wiped away by explosion. 3. Striping and fissure of the epithelium of trachea and bronchi of the injured group were detected. 4. The pathological changes observed with SEM were compared to those with LM.
4.A Morphometric Study of the Lungs in Blast Injured Rats
Journal of Third Military Medical University 1988;0(05):-
The morphological changes of the rat lung with blast injury are quantitified with a stereological method. After blast the pulmonary capillary volume and internal surface area decreased significantly, arithrnatic and harmonic mean thickness of the air-blood barrier, the volumes of P'MN and platelet in capillury increased remarkably. The morphometric lung diffusion capacity of oxygen (DLO2) is reduced markedly mainly due to the decrease of diffusion capacity of air-blood barrier and erythrocyte. The change of DLO2 is closely correlated with the arterial blood oxygen pressure, indicated that the damage of pulmonary capillary is one of the main causes of alveolar bleeding and the early respiratory insufficiency. A mathematic relation can be established between the intensity of the blast wave and the corresponding morphological changes of the injured lungs.
5.Progress in study of semaphorin family with ocular disease
Chinese Journal of Experimental Ophthalmology 2011;29(5):477-480
Semaphorins is the one of guidance molecule families.It is proved to have wide physiological function in the development of neutron and play important role in the pathogenesis of retinal degenerative diseases,gangliocyte apoptosis-related diseases and neovascularization.Previous studies showed that Semaphorins distribute in the cornea,lens and retina.Semaphorins play important role in the development of retina,visual system,cornea nerve and reduce the death of retinal ganglion cells(RGCs)caused by glaucoma,retinal detachment and hypoxic ischemic optic neuropathy.Semaphorin family-related gene mutation may be associated with retinal degenerative diseases.Some of the members could also inhibit angiogenesis.Since semaphorins and its receptors participate in the development of the vasculature and nervous systems,they are implied to be the potential new target of ophthalmopathic treatment.The current ptogress in structure and functions of the semaphorin family along with their relationship with ophthalmopathy were summarized in this study.
6.Building and operation of the pharmacovigilance system in the hospital
Chinese Journal of Hospital Administration 2011;27(9):676-679
Objective Effective intervention on the setbacks and safety loopholes of clinical medication, in an effort to explore, establish and improve the ADR watchfulness system in the hospital step by step. MethodsCollection and compilation of ADRs and drug compatibility cases found in 2010 in the hospital. Intervention on drugs of safety risk exposure or medication factors by means of the ADR prewarning mechanism, medical rounds by hospital's directors regarding drug issues, communication between pharmacists and clinicians, ADR monitoring leadership team, and pharmaceutical affairs council. Results 143 cases of ADR were interfered with among all the 393 ADR cases reported by clinical departments in 2010, accounting for 36.4% of all the reported cases. ConclusionHospitals need to pay more attention to the monitoring, analyzing and evaluation of ADRs, and take efficient intervention means to make drug use more rational and ensure safe medication for the people.
7.Significance of ARHI protein in adenocarcinoma of the uterine cervix
Chinese Journal of Postgraduates of Medicine 2011;34(24):1-3
ObjectiveTo detect the expression of ARHI protein in adenocarcinoma of the uterine cervix and normal uterine cervix tissue, and explore the pathogenesis of cervical cancer. MethodsThe expression of ARHI protein in 30 cases of adenocarcinoma of the uterine cervix tissue and 30 cases of normal uterine cervix tissue was detected by immunohistochemistry and analyzed the relationship between ARHI protein and adenocarcinoma of the uterine cervix. ResultsThe expression of ARHI protein in adenocarcinoma of the uterine cervix tissue[46.67%(14/30)]was lower than that in normal uterine cervix tissue[90.00%(27/30)],the difference was significant (P<0.05). There was intimate correlation between ARHI protein and histological grade, FIGO stage of adenocarcinoma of the uterine cervix tissue (P < 0.05), there was no correlation between ARHI protein and lymphatic metastasis (P>0.05). ConclusionsThe expression of ARHI protein in adenooarcinoma of the uterine cervix decreases which indicates the expression of ARHI protein take part in the carcinogenesis of adenocarcinoma of the uterine cervix. It can be used as a new diagnostic indicator of adenocarcinoma of the uterine cervix.
9.The clinical effect of SMA Concentrator and Tension Band Fixation for the Treatment of Patellar Comminuted Facture
Chinese Journal of Primary Medicine and Pharmacy 2010;17(14):1903-1904
Objective To compare the clinical effect between SMA concentrator and tension band internal fixation for the treatment of patellar comminuted facture. Methods Retrospective analysis of 132 cases of patellar fracture surgery patients,72 cases of them with internal fixation by SMA concentrator,the other 60cases with tension band internal fixation. Results All patients were followed up for 6 to 16 months. The recovery rate of sma concertrator was 95.8% and that of tension hard internal fixation was 88. 3%. Conclusion Using SMA concentrator to treat patellar comminuted fracture was a better treatment.