Objective To summarize the nursing experience of interventional therapy in radiology interventional department so as to shorten the time of interventional therapy and elevate the therapeutic effect of it. Methods Combined with the literature related and the features of interventional therapy, the preoperative preparation and nursing ex-operative preparation and nursing experience of more than 8,000 patients with interventional therapy in our department were summarized. Results All patients went through the therapy successfully without bad feeling during operation. Nurses assisted doctors well and no malpraxis happened. Conclusion Thinking highly of preoperative nursing, postoperative care and patients protecting might improve the efficiency and also might decrease either the impact from other factors or harmful experience personally during operation.

Objective: To study the different pharmacodynamic effects of Persicae Semen extract (PSE) on the blood circulation disorder of rats induced by cold congeal and blood stasis syndrome (cold syndrome, CS), and heat congeal and blood stasis syndrome (heat syndrome, HS). Methods: Eighty rats were randomly divided into eight groups including normal control group of CS, model group of CS, PSE (8 g/kg) group of CS, Chanxiong Rhizoma (8 g/kg) group of CS, normal control group of HS, model group of HS, PSE (8 g/kg) group of HS, and Salviae Miltiorrhizae Radix (14 g/kg) group of HS. The two rat models were established by freezing and injection of carrageenan solution. The rats in each group were ig administered once daily for 7 d. The blood flow velocity (Fve) and blood viscosity (Vis) were detected; The organs (such as heart, lung, liver, kidney, and spleen) were taken and observed by histopathological analysis; The diameters of tiny blood vessels were measured by pathology image analysis software, and the thrombosis and tissue injury were observed. Results: PSE increased Fve but decreased Vis in CS and HS rats (P < 0.05), made the small artery in CS rats systolic, while that in HS rats diastolic (P < 0.05). The organ injury severity score indicated PSE could attenuate the injury of many organs (such as heart, lung, liver, and kidney) in CS rats, but only attenuated the injury of kidney in HS rats (P < 0.05). Conclusion: PSE could improve the blood circulation disorder induced by CS and HS. The different effects of PSE on the two kinds of syndromes include the regulation of the diastolic and systolic states of rat small artery and the different protection of rat organs.

Objective To evaluate the feacibility of microalbumin(MA),alpha-1 -raicroglobulin (?1-MG) ,N-acetyl-beta-D-glucosaminidase (NAG), retinol-binding protein (RBP)as predictors of outcome in critically ill patients. Methods A prospective study was underwent in 30 critically ill patients.Urinary samples were collected at ICU admission and on the third,seventh ICU day for MA,?1-MG,NAG,RBP measurement.The severity of illness was assessed by APACHE II score calculated on the first ICU day,and the degree of organ dysfunction was assessed using SOFA score calculated on the first,third,seventh ICU day. Results MA,?1-MG,the durations of ICU stay and mechanical ventilation,APACHE II score, SOFA score were relative factors of MODS and death in ICU. There was significant association of APACHE II with MA (r=0.397),?1-MG (r=0.448), and RBP (r= 0.465), respectively. The area under ROC curve of APACHE II score,SOFA score,MA,?1-MG, RBP,NAG to predicate the death in ICU were 0.875 ( P

Humans ; Occupational Diseases ; prevention & control

ObjectiveTo investigate the effects of intense pulsed light(IPL) and radiofrequency radiation on the appearance,histopathological manifestation,dermal depth and collagen content in BALB/c mouse skin.MethodsThe back of BALB/c mice was irradiated with intense pulsed light(IPL group,n =9),radiofrequency (RF group,N =9),IPL and radiofrequency (IPL+RF group,n =9) respectively,for 4 sessions at 1-week intervals followed by 2 sessions at 2-week intervals.Three mice remaining untreated served as the control group.The appearance of skin on the back of mice was observed at different time points after irradiation.Some mice were sacrificed and skin specimens were obtained from the back at week 4,8 and 12 after the first irradiation.Hematoxylin and eosin staining was performed to observe the histopathological manifestation and measure the dermal depth of mouse skin,and Masson staining to detect the expression of collagen fiber in mouse skin.ResultsNo local adverse effects were observed in the back skin of mice after irradiation with IPL or radiofrequency.Since the 8th week after the first irradiation,the dermal layer had appeared to be thickened,with an increase in the content of collagen fiber and extraeellular matrix,in the IPL group,RF group and IPL+ RF group compared witb the control group,and the increase was more obvious in the IPL+RF group than in the IPL group and RF group (all P ＜ 0.05 ).Increased collagen fiber was densely arranged in irradiated mice.There was no apparent thickening of skin epidermis after irradiation.ConclusionsBoth IPL and radiofrequency can stimulate an increase in dermal collagen production in mice,and a synergistic effect exists between IPL and radiofrequency in the biostimulation of collagen synthesis.

The apprentice system is the principal succession method of ancient Chinese medicine. Masters pass down knowledge via verbal instructions as well as personal deeds, and apprentices are unconsciously influenced deeply within by what they see and hear from masters. That is where the strong point of the system. However, at the same time, apprentices are confined by their master’s instructions and learn only a part of the knowledge. It is the profound meaning rather than the form, that truly represents the modern value of the system. Traditional Chinese medicine stresses the cultivation of medical ethics, purification of learning motivation, study of classic works, solid foundation of basic skills and clinical practice. It also advocates that apprentices should be led and taught in accordance to his aptitude.

OBJECTIVE:To prepare Stemoninine orally disintegrating tablets,and to optimize its formulation and preparation technology. METHODS:Direct powder compression method was used to prepare Stemoninine orally disintegrating tablets. Using material angle of repose,disintegration time and taste evaluation as index,single factor test was used to screen several factors as bulking agent,disintegrating agent,glidant and flavoring agent;using disintegration time as index,L9(34) orthogonal test was used to optimize the formulation with ratio of MCC+mannitol,PVPP,silica powder and aspartame+stevia as factors. Validation test was also conducted. RESULTS:Optimized formulation was that MCC+mannitol(1∶1)was 50%,PVPP was 20%,silica powder was 2% and aspartame+stevia(10∶1)was 7%. 3 batches of prepared Stemoninine orally disintegrating tablets were smooth in sur-face and good in taste;their disintegrating time was(22.6±2.1)s,and weight variation,hardness,contents were within the speci-fied range (all RSD≤0.97%,n=3). CONCLUSIONS:The formulation and technology of Stemoninine orally disintegrating tab-lets are reasonable,and the quality indexes are all in line with the requirements of orally disintegrating tablets.

Objective To understand the clinical characteristics of patients with advanced schistosomiasis in Yingcheng City,so as to provide evidences for the assistance work of advanced schistosomiasis. Methods The clinical data of all the ad?vanced schistosomiasis patients in Yingcheng City were collected and analyzed. Results Up to December 30,2014,there were 96 advanced schistosomiasis patients in Yingcheng City,among which,68 cases(70.8%)were male,28 cases(29.2%) were female,and their average age was 64.2 years. Most of the patients(90.6%)were ascitic type,followed by splenomegaly type(5.2%),colon proliferation type(2.1%),and dwarf type(2.1%). Totally 48 cases(50.0%)were positive in immunologi?cal detections,among which 8 cases(8.3%)were positive in ELISA and 12 cases(12.5%)were positive in IHA. For all the 4 indexes of hepatic fibrosis(HA,LN,CIV and PCⅢ),only 15 cases(15.6%)were normal. Conclusions Though Yingcheng City has reached the criteria of transmission control,the hepatic fibrosis of some patients continues to progress. Therefore,the intensity of the treatment and assistance could not be weakened,especially for those of the ascitic type patients.

OBJECTIVE:To study the stability of omeprazole in micro-pump by continuous administration.METHODS:RP-HPLC were used to determine the concentrations of omeprazole at different times in micro-pump after administrcotion24h by simulating the dose mode in clinical.RESULTS:Omeprazole for injection was stable in6h after administration.CON?CLUSIONS:The time of taking omeprazole via micro-pump should be controled in6h.