1.Ocular manifestations of acquired immunodeficiency syndrome
Chinese Journal of Ocular Fundus Diseases 2010;26(5):423-426
Objective To observe ocular manifestations of acquired immunodeficiency syndrome (AIDS). Methods Fourty-two AIDS patients (66 eyes)with ocular complaints received examinations of visual acuity, slit-lamp microscope, ophthalmoscope and fundus fluorescence angiography (FFA). The results were retrospectively analyzed. ResultsThere are five types of ocular findings, including cytomegalovirus (CMV) retinitis (37 eyes, 56.0%), retinal microvasculopathy of human immunodeficiency virus (21 eyes, 32.0% ), optic nerve diseases (three eyes, 4.5 % ), retinal neuroepithelial layer detachment (two eyes, 3.0%) and uveitis (three eyes, 4.5%). Conclusions The common ocular manifestations showed progressive necrotic retinitis, retinal hemorrhage and retinal vasculitis and attenuated, cotton-wool spots in AIDS patients.
2.The Influence of Transitional Care on the Quality of Life and Psychology of Patients with Acute Myocardial Infarction after PCI
Chinese Medical Ethics 2016;29(2):243-245
Objective:To discuss the effect of transitional care on the quality of life ( QOL) and psychology in acute myocardial infarction patients after PCI. Methods:The acute myocardial infarction patients accepted PCI in our university affiliated hospitals were selected and divided into experimental group and control group randomly. The control group received routine care during the period of hospitalization. The experimental group received transi-tional care including home visits, massed learning, telephone follow-up, and the establishment of WeChat and QQ group. The QOL, anxiety, and depression were investigated pre-intervention and six months post-interven-tion to evaluate the effect of transitional care. Results:After transitional care six months later, the QOL scores in the experimental group were significantly higher than those in the control group, SAS and SDS scores were lower in experimental group than those in the control group ( P<0 . 05 ) . Conclusions:Transitional care for acute myocar-dial infarction patients after PCI could improve their QOL, and relieve their anxiety and depression level in different degrees.
3.Efficacy of alprostadil and Shenkang on regulating renal function and lipids in patients with chronic renal failure
Clinical Medicine of China 2014;30(12):1303-1306
Objective To investigate efficacy in Alpmstadil and Shenkang on regulating renal function and lipids in patients with chronic renal failure (CRF).Methods Ninety-eight cases of CRF patients were collected for the study,and 1:1 randomized,double-blind experiment grouping principles were used in the current study.All cases were divided into study group and the control group (49 cases of each group).The two group were given the high quality low protein,low fat low salt diet,inftion control,diuretic swelling,correct acidosis,buck,correction of electrolyte imbalance and other conventional treatment.The patients in study group on the basis of conventional therapy were given 20 g Alprostadil injection + 100 ml saline,intravenous infusion of 1times/d,and 100 ml Shenkang injection +300 ml 5% glucose the solution,intravenous infusion of 1 times/d.While patients of control grrup on the basis of conventional therapy plus 200 mg Ligustrazine + 250 ml 5%Glucose Injection,intravenous infusion of 1times/d.Two groups were treated for 14 d.Before and after treatment,renal function,lipid metabolism,adverse drug reactions were observed and determined.Results There was no significant difference in term of renal function between two groups before treatment(P > 0.05).After treatment,the levels of serum creatinine,blood urea nitrogen,24 h-Urine protein and creatinine clearance(Ccr) in study group were (313.7 ±66.2) mmol/L,(15.3 ±2.9) mmol/L,(1.24 ±0.45) g/24 h and (35.7 ±5.4) mmol/L respectively,significant different from those in control group ((358.4 ± 53.9) mmol/L,(18.4 ± 3.0) mmol/L,(1.57 ±0.39) g/24 h and (28.4 ±4.3) mmol/L;t =3.754,7.864,5.873,4.312,P <0.05).There was no significant difference in term of blood fat between two groups before treatment (P > 0.05).In study group,the levels of glycerin trilaurate,cholesterol total,high density hpoprotein cholesterol,low density lipoprotein cholesterol were significantly different than those in the control group ((2.12 ± 1.26) mmol/L vs.(2.32 ± 1.34) mmol/L,(4.91 ± 1.43) mmol/vs.(5.35 ± 1.31) mmol/L,(1.39 ± 0.43) mmol/L vs.(1.23±0.37) mmol/L,(2.39 ± 0.68) mmol/L vs.(2.73 ± 0.88) mmol/L; t =3.876,4.661,5.387,8.543 ; P < 0.05) after treatment.There were no adverse drug reactions in both groups.Conclusion Combined usage of alprostadil and shenkang injection could significantly improve the patient's renal function,lipid metabolism disorders and shows no significant adverse reactions,suggesting that it is worthy of clinical application and promotion.
4.Effect of Motor Relearning Program on the Balance Function of Stroke Patients
Chinese Journal of Rehabilitation Theory and Practice 2006;12(12):1093-1094
Objective To observe the effect of motor relearning program (MRP) on balance function of stroke patients.Methods Sixty stroke patients were randomly divided into the MRP group and control group with 30 cases in each group. The patients of the control group were trained with proprioceptive neuromuscular facilitation (PNF) therapy; those of the MRP group were trained with the MRP therapy. The balance function of all patients was assessed with the Fugl-Meyer Balance Function Assessment before and after training.Results After training, the scores of Fugl-Meyer Assessment of all patients increased ( P<0.05), but scores of the patients of the MRP group were significantly higher than that of the control group ( P<0.05).Conclusion The MRP training can improve the recovery of balance function of stroke patients.
5.Reaction Kinetics of Monochlorotriazine Reactive Dyes with Neucleophilic Groups in Silk by High Performance Liquid Chromatography
Min SHAO ; Jianzhong SHAO ; Jinqiang LIU ; Ping LI
Chinese Journal of Analytical Chemistry 2009;37(7):989-993
Using Isopropyl amine (0.003 mol/L), p-methyl-phenol (0.03 mol/L) and methanol (1 mol/L) for simulating amino groups, phenol groups and hydroxyl groups in silk fibroin respectively, the reaction rate of different nucleophilic groups in silk with monochlorotriazine reactive dye was studied at various temperature and pH by high performance liquid chromatography. It was found that the overall reaction rate of dyes′ phenolysis was by far higher than that of ammonolysis and alcoholysis on the conditions of 70-95 ℃ and pH=8-10. The phenolysis overall reaction rates of C.I. reactive red 24 and C.I. reactive orange 2 were 8.5 and 12.5 times of their ammonolysis′, and 23 and 50 times of their alcoholysis′ in the term of pH 9 and 95 ℃. The phenolysis efficiencies of those two dyes were 47.4 and 96.3, the ammonolysis efficiencies were 4.6 and 6.9, and the isopropyl amine, p-methyl-phenol and methanol to simulate the silk fibroin, the reaction selectivity between the monochlorotriazine reactive dyes and nucleophilic groups in silk fibroin was investigated. It was deduced that monochlorotriazine reactive dyes are suitable for dyeing silk on the conditions of about 85 ℃ and pH=8-9, and under this condition, phenol groups are the major groups in silk dyeing with monochlorotriazine reactive dyes, amino groups are the minor groups, and the contributions of hydroxyl groups can be neglected.
6.Diagnosis and prognosis of systemic juvenile rheumatoid arthritis.
Li-hua SHAO ; Min WEI ; Mei DONG
Chinese Journal of Pediatrics 2003;41(1):46-47
Arthritis, Juvenile
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classification
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diagnosis
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therapy
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Child
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Female
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Follow-Up Studies
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Humans
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Male
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Prognosis
7. A preliminary study of the relationship between the uterine junctional zone and outcome of intrauterine adhesions
Medical Journal of Chinese People's Liberation Army 2016;41(4):301-306
Objective To investigate the influence of degree of the injury in uterine junctional zone (JZ) of intrauterine adhesions (IUAs) patients on postoperative pregnancy outcomes by magnetic resonance imaging (MRI). Methods Design: Retrospective observational study. Setting: Navy General Hospital of PLA, Beijing. The study included ninety-two patients undergoing preoperative pelvic MRI from June 2011 to June 2014, and they were diagnosed as IUA by hysteroscopy, and hysteroscopic adhesiolysis was conducted under the guidance of abdominal ultrasound. All patients had tried to be pregnant for longer than six months. According to whether uterine junctional zone (JZ) was injured or not, the patients were divided into two groups: group A (JZ was normal) and group B (JZ was partly or completely injured). All patients were followed up with telephone comunication regarding postoperative pregnancy outcome within two weeks in August 2015. The difference of severity of IUAs and pregnancy outcome was compared. Results There were 51 and 41 IUAs cases in Group A and Group B, respectively. According to European Society of Gynecological Endoscopy (ESGE) classification of IUAs, the number of mild, moderate and severe IUA cases were 20, 24 and 7, respectively, in group A; and 10, 12 and 19, respectively, in group B. The proportion of severe IUA cases was significantly higher in group B than in group A (P=0.001). Forty-six of 92 IUAs cases had been pregnant, the pregnancy rate was 50%. Among them 4 had conceived twice. Twenty-one IUAs had given live birth (one had given birth to a pair of twins), and 10 were in pregnancy. The live-birth delivery rate was 42%, and the pregnancy loss rate was 38%. Thirty-one and fifteen IUAs had been pregnant in group A and group B respectively, the pregnancy rate was higher in group A than in group B (60.8% vs 36.6%, P=0.021). The live-birth delivery rate was higher in group A than in group B (47.1% vs 31.3%, P=0.365), while the pregnancy loss rate was higher in group B than in group A (29.4% vs 56.3%, P=0.117), but the difference was not statistically significant. Conclusions The severity of IUAs was associated with the degree of injury of uterine JZ. Especially, when JZ was completely injured, it was meant to have severe IUAs. For IUAs, injured uterine JZ may significantly decrease the postoperative pregnancy rate and live-birth delivery rate, and increase in the pregnancy loss rate. Evaluation of JZ may offer new perspectives to estimate the severity of IUA and the outlook of pregnancy. So it is recommended to evaluate the degree of injury of uterine JZ as an independent predictor for postoperative pregnancy outcome of IUAs. For severe IUAs, once JZ was extensively or completely injured, the outcome of pregnancy may be very poor.
8.Effect of CBP on the level of blood lactic acid and 6 h lactic clearance rate in the patients with severe sepsis
Yuedong LI ; Jingquan WANG ; Min SHAO
Acta Universitatis Medicinalis Anhui 2014;(2):251-253,257
Objective To investigate the effect of continuous blood purification ( CBP) on the level of blood lactic acid and 6 h lactic clearance in the patients with severe sepsis. Methods 48 patients with severe sepsis were cho-sen in ICU, and they were randomly divided into two groups: control group ( n=20 ) and CBP group ( n=28 ) . Their arterial blood lactic acid level was tested on admission and was retested 6, 24, 48 and 72 h after treatment. The patients’6 h blood lactic clearance rate and the corresponding APACHEIIscore were calculated. The level of arterial blood lactic acid and the score of APACHE IIwere compared at different time. 6 h blood lactic clearance, the period of stay in ICU and the 28-days mortality were compared too. Results The level of lactic acid and the score of APACHE II after 24 h were lower in CBP group, and the period of stay in ICU was shorter in CBP group than that in control group at different time ( P<0.05 ) . 6 h blood lactic clearance was higher than that in control group (P<0.05). Moreover, the 28-days mortality had no significant difference in CBP group. Conclusion The CBP plays an important role in clearing the blood lactic acid and it can reduce the severity of the sepsis as well as shorten the period of stay in ICU.
9.Prevention and treatment of complications of propoful sedation and anesthesia during gastroscopy
Wanwen ZHANG ; Xiaogang SHAO ; Min WANG
Chinese Journal of Digestive Endoscopy 1996;0(05):-
Objective To alleviate or prevent the complication of propoful sedation and anesthesia during gastroscopy. Methods One thousand three hundred and fifty eight patients were undergone gastrosco-py under propoful sedation and anesthesia. Results Although some patients with intravenous use of propofol their blood pressure, heart and respiratory rate decreased in different extents, but others remained in normal range. During the operation, two cases(0. 15% )had hypotension which could be corrected after intravenous use of ephetonin; three cases (0. 22% ) had bradycardia that was restored after intravenous use of atropine; three hundred and eighteen cases (23. 42% )had cough which could be prevented by increasing the first dose of propofol and avoiding the pharyngeal simulation derived from operation; sixteen cases( 1. 18% )had serious chock accompanied with decreasing of blood oxygen saturation which could be alleviated by aspirating the guttural secretion, driving up the patients mandible and increasing oxygen inhalation, keeping the gastroscope dry and avoiding pumping water or air as passing through epiglottis are the effective methods in preventing chock. Forty six cases (3. 39% ) complained of pain in the injection site which could be alleviated by choosing a major vein and injecting drug slowly; forty three cases(3. 17% ) had nausea and two cases(0. 15% ) had phreno muscular spasm which could be alleviated or prevented by skilled manipulation; thirty nine cases (2. 87% )had vertigo after regaining consciousness, keeping in bed or deferring to wake the patient up are very effective in preventing and alleviating this symptom. Conclusion Although gastroscopy under propoful' s sedation and anesthesia is safe and effective, logical precautions are the keys to attain success and lessen complications.
10.Safety of Plant Growth Regulators to Crops and Environment
Min ZHAO ; Fengyun SHAO ; Shuxin ZHOU
Journal of Environment and Health 1992;0(05):-
In the present paper, the safety of several major plant growth regulators to environment, agricultural products and animals was discussed synthetically. Paclobutrazol is stable in physical and chemical properties with slow degradation, and is able to secondly control the plant growth obviously, but it is degradable and becomes mutagenic substance, it can be enriched in the soil and is able to bio-magnify. Uniconazole is quick degradable with less residue. Ethephon is potentially mutagenic to the animals, it is degradable and can produce residues which will be harmfulto animal body. Moreover, their residual quantity differs with different organs in a plant and their residue in the leafage of several plants is in a high level.