Objective To analyze the clinical treatment and curative effect of heart failure complicated with hyponatremia in elderly patients.Methods The clinical data were retrospectively analyzed in 72 aged patients with heart failure and hyponatremia,by controlling the intake of fluid and using diuretics and the drugs of heart failure,not restrict a low sodium diet,by adding sodium chloride,analyzed the effect and prognosis after moderate supplement of sodium for 7 days.Results The use of loop diuretics reduced cardiac edema,renew and sodium chloride without aggravating heart failure or hypernatremia,total effective rate was 95.83％,and it was safe and effective.Conclusion For the elderly patients with heart failure complicated with hyponatremia,should be based on the conventional symptomatic treatment of heart failure,correction of hyponatremia,improve cardiac function and prognosis of patients.

Aggressive B-cell lymphoma is characterized by malignant behaviour and rapid progression.Patients are prone to drug resistance or relapse of disease.The 19th European Hematology Association (EHA)annual congress explored several aspects about aggressive B-cell lymphoma.PET-CT examination provided new tools for the indication of prognosis.The elevated dose of rituximab improved the outcome of elderly male patients.Novel drugs or methods including bortezomib,ABT-199,combined targeted therapy and CNS prophylaxis have shown encouraging results in various clinical trials which provide new hope for patients with aggressive B-cell lymphoma.

There are large amount of Chinese herbal medicine used in folk custom of our country. Most of these medicines are related with hygiene and health care. The usage of these medicine included avoiding dirty, preventing diseases, restoring convalescence, health protection, cosmetology, bathing, and daily effective medical prescription. Folk custom has the characteristics of regionality, consistency, and nationality,ete. Some of traditional Chinese medicine originates from folk custom. Therefore, the research of medicine used in folk custom may help to the development of traditional Chinese medicine.

Hodgkin lymphoma (HL) originates from the lymphoid hematopoietic tissues and has a good treatment outcome with relatively high cure rate.Early stage HL is curable with abbreviated chemotherapy plus involved-filed radiotherapy or chemotherapy alone.However,patients with refractory or relapsed disease still lack effective treatment.In recent years,with the application of risk stratified treatment,novel drugs such as brentuximad vedotin,and PET-CT evaluation,significant progress has been made in prognosis and treatment of HL

Apoptosis ; Humans ; Periodontitis ; pathology

Epidemiological and animal studies have demonstrated that dietary lower intake of n-3 polyunsaturated fatty acids (n-3 PUFAs) and(or) higher intake of n-6 polyunsaturated fatty acids(n-6 PUFAs) leading to imbalance of their ratios are closely related to obesity.The mechanisms underlied are involved in PUFA′s effects on fatty acid synthesis and oxidation,adipocyte proliferation and differentiation and leptin expression.At transcription level,PUFAs can regulate the activities of peroxisome proliferator-activated receptors and CCAAT enhancer bin-ding proteins.

Objective To compare analgesic efficacy of intravenous postoperative and preemptive analgesia with flurbiprofen axetil combined with small dose of morphine and with morphine alone. Methods One hundred and twenty patients were randomly divided into four groups: group A,morphine 30 mg +0.9% NaCl for postoperative analgesia,n=30;group B,morphine 20 mg +0.9% NaCl for postoperative analgesia,n=30;group C,flurbiprofen axetil 100 mg + morphine 20 mg +0.9% NaCl for postoperative analgesia,n=30;group D,flurbiprofen axetil 100 mg before operation + morphine 20 mg +0.9% NaCl for postoperative analgesia,n=30.The drugs in each group were diluted to 100 mL and infused by a pump at a rate of 2 mL/h with a patient-controlled analgesia(PCA)bolus of 2 mL after a loading dose of 5 mL.The visual analogue scale(VAS),demanding times for PCA and incidence of side effects were recorded during the period of postoperative 24 h. Results The VAS of group B at 3 h after operation was significantly higher than those of the other three groups(P

Objective To analyse the key influential factors for research performance of medical colleges and provide evidenes for further research management. Methods A questionnaire suvery was carried out in Shanghai Jiaotong University School of Medicine.Through stratified cluster sampling,those who assumed all ranks of projects from 2001 to 2006 in Basic Medical College and some affiliated hospitals were investigated.Two hundred and sixty questionnaires were sent out and 211(81.2%) were reclaimed.Delphi and comprehensive analysis were used to measure the research performance,and multi-Logistic regression was employed to analyze the influential factors for research performance.Results The key influential factors for research performance included research team,research investment,age of researchers,international exchanges and communications,and extra working hours for research.Conclusion To improve the research performance of medical colleges,it is most important to strengthen research team development,expand research investment,promote acedemic exchanges and communications,and initiate dedicated spirit for research work.

With the development of the quality of life, the morbidity of hyperuricemia is increasing year by year. At the same time, it appears that this disease attacks the young people currently. As the study of pathogenesis of hyperuricemia advanced, a series of uric acid transporters were found during this process. Meanwhile, the definition of transporterome was proposed. They were divided into three groups according to the functions: reabsorption proteins, excretion proteins and skeleton proteins. At moment, the drugs for hyperuricmia mainly include uric acid composition inhibitors and uric acid excretion promoters. Since the excretion of uric acid plays a leading role during the process of attack of hyperurecimia, it makes sense to explore Chinese medicines with clear mechanism targeting the transporterome. Therefore, this paper would focus on transporterome and summarize the mechanisms of Chinese medicines in treating hyperuricemia.
Animals ; Biological Transport ; Carrier Proteins ; antagonists & inhibitors ; genetics ; metabolism ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Hyperuricemia ; drug therapy ; metabolism ; Uric Acid ; metabolism

Abortion, Habitual ; therapy ; Female ; Humans ; Medicine, Chinese Traditional ; methods ; Pregnancy