Objective To know the efficacy of oral nursing by visible electric toothbrushes among patients with peroral endotracheal intuabtion. Methods Divided 108 trauma patients with peroral endo-tracheal intubation and clear consciousness into the research group and the control group randomly, there were 54 cases in each group. Routine oral nursing cares were used in the control group, while the visible electric toothbrushes was used in the research group. Compared the efficacy of oral nursing between the two groups. Results The incidence rate of mouth odor, plaque index and oral infection in the research group were better than those of in the control group. Conclusions Using visible electric toothbrushes for trau-ma patients with oral endotracheal tube is a kind of effective and feasibility method, which should be devel-oped in the clinical field.

To develop optimal shift systems for an improvement of work schedule satisfaction, health and work productivity, the effects of the direction of the rotational work shifting on the circadian rhythm and adaptation of physiological components and work mistakes were investigated in nursing students. Two groups of seven volunteers participated as experimental subjects, apd seven to twenty nursing students participated as a control group. The directions of rotation work shift were as follows CW(clockwise)-shift system rotation in the direction of day shift(3 days), evening shift(3 days), off duty(l day) and night shift(5 days), and CCW (counterclockwise) -shift system rotation in the reverse direction. Urinary Na, K, and Cl levels were measured with ion-selective electrodes. The levels of performance were measured by a questionnaire to determine the number of mistakes in 12 specific items during duty. The disturbance of Na the circadian rhythm was seen on day and night shifts, especially in the CCW-rotation shift system, and the magnitude of the daily variation was greatest in the CCW-rotation system. The daily rhythms of K and Cl shifted to the right on the evening shift, and the rhythms were reversed on the night shift, which suggests that they adapted to the altered shift work. However, the levels of Cl were higher in day and night shift workers, especially in CCW-shift system. In the ease of urine salts, it seems that the students in CW-shift system more easily adapted to the altered shift. The incidence of mistakes during work were more frequent on the CCW shift than in the CW shift. These data indicate that the direction of rotation effects the worker's health and work performance. These results indicate that the CCW rotation of shift work makes it more difficult for the workers to adapt to the shift on a physiological level, and has many more negative effects on the shift workers' health when compared with the CW rotation. Thus, a clockwise rotating shift system seems to be more desirable for the optimal health and performance of nurses.
Appointments and Schedules ; Circadian Rhythm* ; Efficiency ; Humans ; Incidence ; Ion-Selective Electrodes ; Salts ; Students, Nursing ; Volunteers ; Surveys and Questionnaires

No abstract available.
Adolescent* ; Humans ; Suicide*

BACKGROUND: Both c-fosand heat-shock protein (HSP) 70 genes are closely relevant with and participate in the occurrence and development of blood stasis syndrome of primary hypertension. It is importance to study on their correlation for prevention of primary hypertension.OBJECTIVE: Immunohistochemical method was used to determine the expression of HSP70 and c-fos genes in blood stasis syndrome of primary hypertension so as to probe into their correlation.DESIGN: Case analysis.SETTING: Department of Traditional Chinese Medicine, Medical College of Jinan University.PARTICIPANTS: Totally 148 cases of primary hypertension were selected, diagnosed in ward and clinic of Department of Cardiac Vascular Internal Medicine of Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine from March 2002 to march 2003, of which, 80 cases were male and 48 cases were female.INTERVENTIONS: At 7:30 to 8:00 in the morning on the 3rd of hospitalization, 2 mL intravenous blood was collected in fasting for immunohistochemical determination of HSP70 and c-fos genes. Evaluative standards:negative expression (-), no brown-yellow stained cell appeared; positive expression (+), positive cell count of each high power field ＜ 20％; dominant expression (++), positive cell count of each high power field was in the range from 20％ to 50％; strong positive expression (+++), positive cell count of each high power field was ＞ 50％. Ridit analysis statistical method was used for the correlation analysis.MAIN OUTCOME MEASURES: Expression of HSP70 and c-fos genes.RESULTS: Totally 148 cases of primary hypertension participated in the experiment and the blood sample of all of those entered the result analysis.① Six cases presented positive expression of both HSP70 and c-fos genes.② Four cases presented dominant expression of HSP70 gene and positive expression of c-fos gene respectively. ③ Twelve cases presented strong positive expression of HSP70 gene and positive expression of c-fos gene respectively. ④ Six cases presented positive expression of HSP70 gene and dominant expression of c-fos gene respectively. ⑤ Nineteen cases presented dominant expression of both HSP70 and c-fos genes. ⑥ Sixteen cases presented strong positive expression of HSP70 gene and dominant expression of c-fos gene respectively. ⑦ One case presented positive expression of HSP70 gene and strong positive expression of c-fos gene respectively. ⑧ Twenty-eight cases presented dominant expression of HSP70 gene and strong positive expression of c-fos respectively. ⑨ Fifty-six cases presented strong positive expression of both HSP70 and c-fos genes. ⑩ The grade of positive expression presented significant correlation between HSP70 gene and c-fos gene (R =0.281 1-0.644 6, P＜0.01).CONCLUSION: In blood stasis syndrome of primary hypertension, the high expression presents in both HSP70 and c-fos genes, indicating remarkably correlation.

Objective To observe the clinical effect of low-dose dexmedetomidine plus tramadol hydrochloride for patient-controlled interscalene analgesia (PCIA) after laparoscopic hysterectomy.Methods Seventy ASA Ⅰ ～ Ⅱ female patients with elective laparoscopic hysterectomy were randomly divided into two groups:the tramadol hydrochloride PCIA group(group A),and the dexmedetomidine plus tramadol hydrochloride PCIA group(group B),35 cases in each group.Visual analog scale (VAS),Ramsay scores,Sleepiness scale and the tramadol consumption were recorded.And the adverse events such as nausea and vomiting,dizziness and respiratory depression were observed.Results All patients got good analgesia in both two groups,VAS scores ＜ 4.In group B,VAS scores of postoperative 24h and 48h were (3.2 ±0.3) (2.7 ±0.3),which were significantly lower than (3.8 ±0.4) and (3.2 ± 0.2) in group A (t24 =7.099,t48 =8.204,all P ＜ 0.05).Sleepiness scale (3.1 ± 0.7) in group B was lower than group A (4.2 ± 0.8) (t =6.122,P ＜ 0.05),while there was no difference of Ramsay scores between two groups (P ＞ 0.05).And in group B,the tramadol consumption [(625.2 ± 113.7) mg] and the intramuscular pethidine times (2.1 ±1.9) were fewer than group A[(782.9 ± 102.6)mg,(5.2 ±2.2) times] (t =6.092,6.309,all P ＜0.05).Conclusion Low-dose dexmedetomidine may improve the effect of tramadol hydrochloride PCIA after laparoscopic hysterectomy,and help to reduce the tramadol consumption and adverse effects.

Objective To investigate the risk factors and prevention of recurrent laryngeal nerve injury during thyroid operation.Methods The clinical data of 2180 patients with thyroid operation were retrospectively analyzed.The potential relationship of the incidence rate of recurrent laryngeal nerve injury were evaluated,such as age,gender,nature of lesions,thyroid pathology,anesthesiology,operation times,whether or not to reveal recurrent laryngeal nerve.Results The overall incidence rate of recurrent laryngeal nerve injury postoperatively was 2.7％ (59/2180).The incidence rate of recurrent laryngeal nerve injury in patients with thyroid malignant neoplasms,repeated surgery and without reveal recurrent laryngeal nerve were 6.7％ (33/492),5.6％ (15/267),4.4％ (39/891),significantly higher than those in the patients with thyroid benign neoplasms,first time operation and with reveal recurrent laryngeal nerve [1.5％ (26/1688),2.3％ (44/1913),1.6％ (20/1289)] (P ＜ 0.01).In the patients with thyroid dorsal lesion,the incidence rate of recurrent laryngeal nerve injury in the patients without reveal recurrent laryngeal nerve was significantly higher than that in the patients with reveal recurrent laryngeal nerve[13.7％(29/212) vs.2.9％(12/417),P＜0.01].Conclusion Thyroid malignant neoplasms,repeated surgery and without reveal recurrent laryngeal nerve can increase the risk of recurrent laryngeal nerve injury,routine reveal recurrent laryngeal nerve in the patients with thyroid dorsal lesion can decrease the incidence rate of recurrent laryngeal nerve injury.

2-(3-benzoylphenyl)propionitrile which is an important intermediate of ketoprofen was synthesized through phase-transfer catalytic by four steps, involving Friedel-crafts reaction, bromination and cyanation. Pure compound was obtained, and the content of crystal was about 98%.AIM　The content of 2-(3-benzoylphenyl)propionitrile was improved. METHODS　Phase-transfer catalytic methylation and suitable method of aftertreatment were used. RESULTS　The yield and content was both improved. CONCLUSION　Phase-transfer catalytic methylation was the best method, and suitable method of aftertreatment was essential.

Objective To observe the effect of potassium sodium dehydroandrographolide succinate for injection (PSDS)combining with smecta enema treatment on children with autumn diarrhea.Methods 102 children patients with autumn diarrhea were selected and divided into the control group,the PSDS group and the combination group with 34 patients in each group.The control group received symptomatic supportive treatment,based upon this,the PSDS group received PSDS,and the combination group adopted PSDS and smecta enema treatment.The treatment effect was compared between the three groups.Results The effect of the PSDS group and the combination group was better than the control group,the effect of the combination group was better than the PSDS group.Conclusions Combination of PSDS with smecta enema treatment for children with autumn diarrhea has significant effect,but enough attention should be paid to peri-anal nursing.

Objective To evaluate the value of renal adipose capsule injection of methyprednisolone by ultrasound guided in treatment of nephritic syndrome.Methods 31 patients with nephritic syndrome were treated with the renal adipose capsule injection of methyprednisolone by ultrasound guided.40mg methylprednisolone was injected into renal adipose capsule of the patients twice a week and each one of them was totally given ten times of the treatment.The urinary protein,plasma albumin,serum creatinine and blood pressure before and after the treatment were measured.Results 29 cases were succeed in this group,and the percentage was 94%,clinical observations of proteinuria were negative.2 cases were repeated after stop interventional treatment.and the percentage was 6%.Conclusion By ultrasound guided interventional treatment and capsula adipose treated for nephrotie syndrome was simple operation,and had precise positioning and significant effect,and it provided a new treatment for clinic.

Bronchopulmonary dysplasia is a chronic lung disease of newborn.In recent vears.its incidence is increasing.Bone marrow derived mesenchymal stem cells(BMSC)have been shown to differentiate into a variety of mesenchymal cell types.It has been shown that these cells can be separated.purificated.amplificated and administered to animals and patients in clinical trials.This article focuses on the pathology.pathogenesis of the bmnchopulmonary dysplasia,and biological characteristics of BMSC,and indicates that the cells in the circulation Can engraft in the lung and offer effective protection against lung injuries.