OBJECTIVE To explore the reason,hazard and preventive method of sharp injuries by analyzing nursing students who had sharp injuries.METHODS A retrospective study of hospital medical sharp injuries were taken among nursing students from Aug 2007 to May 2008.RESULTS There were 30 cases sharp injuries occurred in past year.Needles injuries accounted for 76.7%,and the others for 23.3%.Fifteen cases occurred in operation,and 15 cases occurred after operation.Twenty-three cases worked without gloves;86.7%injuris were on fingers.Hepatitis Bvaccine inoculation rate was 63.3% in 30 cases.CONCLUSIONS Enhancing occupational security education,improving nursing students′ sense of occupational security prevention and standardizing operation progress,can decrease sharp injuries among nursing students.

Objective To design a neonatal nasogastric fixation mount to decrease the complications during nasogastric feeding and facilitate the nurse's operation.Methods The mount was composed of a base,a hose rack,a clamp,a freelyrotating roll ball and a fixation knob.Totally 90 preterm infants hospitalized from January to September 2016 were equally and randomly divided into a fixation mount group,a gravity feeding group and a control group using conventional nasogastric feeding.The incidences of the complications during feeding were recorded including emesis,abdominal distension and apnea,and questionnaire survey was carried out on the nurse's satisfaction for the fixation mount.Results The mount reduced the complications related to nasal feeding,increased the nurse's satisfaction.The fixation mount group had the complications incidence rate (30.0％) significantly lower than those of the gravity feeding group (43.3％) and the control group (53.3％).The nurse's satisfaction in the fixation mount group (93.3％) was higher than those in the gravity feeding group (80.0％) and control group (52.0％).Conclusion The nasograstric fixation mount is applicable for the preterm infants in far-infrared radiation table,warmer and infanette,and thus is worthy promoting clinically.

Objective To investigate the effect of batroxobin on the plasma levels of endothelin (ET) and calcitonin gene-related peptide(CGRP) in patients with acute cerebral infarction(ACI). Methods 60 patients with ACI were randomly divided into therapy group(n = 30) and control group(n = 30),500 ml of 5% GS plus 1.0g ramme of Troxerutin was intravenously dripped par day and ticlopidine 250mg/day in the control group. Based on the control group therapy,Batroxobin was intravenously dripped with 10U on the 1st day and 5U on the 3rd and 5th day for seven days. The plasma levels of ET and CGRP were detected pre and post treatment by radioimmunoassay. Results Plasma levels of ET and CGRP in batroxobin therapy group post treatment ( 81.25±27.38 ) ; ( 44. 13±13.30) ng/L were significantly different from those pre treatment(109. 83±38.24) ; (24. 73±13.59) ng/L (all P＜0. 01 ) ,and were also significantly different from those post treatment in the control group(98.07±30. 39) ; (37.02±12. 41 )ng/L (all P＜0. 01 ). Conclusion Batroxobin can accommodate the equilibration between ET and CGRP, and protect brain cell and blood vessel endothelial cell.

the Purpose of spermatozoon storerooms are setting up for solving the sterile problem.But some storerooms are found for commercial aim such as the spermatozoon storeroom,for celebrities or doctors'.It should not be approved of.The reasons is that it conflicts with such concepts as life equality,ethical relationship among families,and option for sterile couples.We should prohibit the establishment of the spermatozoon storeroom for the commercial purposes.

Objective To investigate the therapeutic effect of traditional Chinese medicine,Songling Xuemaikang Capsule on the individual with cerebral infarction reconvalescent and its mechanism.Methods Patients in control group( n =54) received regularly therapy and treatment group( n =55) was treated with regularly therapy and Songling Xuemaikang Capsule for eight weeks respectively.The clinical therapeutic effeets,Barthel index,hemorheology indexes,serum lipid and C-reactive protein (CRP) were determined.Results The total clinical effective rate in treatment group and control group was 70.9％ and 55.6％ (P ＜ 0.01 ).After eight weeks treatment,the scores of Barthel Index,hemorheology indexes,the amounts of serum lipid and CRP in treatment group were improved significantly as compared to the control group ( P ＜ 0.05 or P ＜ 0.01 ).There was no severely side effect found in this trial.Conclusion Songling Xuemaikang Capsule could partly improve patients clinical outcome and life quality.The clinical efficacy of Songling Xuemaikang Capsule on the individual with cerebral infarction reconvalescent should be related to its functioning to promote the recovery of patients' blood hemorheology,and regulate serum lipid and decrease CRP level.

Objective To explore the relationship between β2-microglobulin and D-Dimer concentration in the pregnancy-induced hypertension patients with kidney injury.Methods The 120 cases of kidney injury pregnancy-induced hypertension patients were enrolled in our hospital from Nov 2010 to Nov 2015 (served as observation group).The levels of BUN,Scr,UA,β2-microglobulin and D-Dimer were detected.The 100 cases of healthy subjects and 120 cases of normal pregnancy women were taken as controls,respectively.Results Compared with healthy control and normal pregnancy women,the levels of BUN,Scr,UA were increased significantly in the observation group (P<0.05).The results also showed that the expression of NGAL,NLRP3,NADPH oxidase subunits,TGFβ,Smad2,Smad3,β2-microglobulin and D-Dimer were sharply increased as compared with the other two group (P<0.05).Conclusion β2-microglobulin and D-Dimer are significantly related with pregnancy-induced hypertension patients with kidney injury and they would be taken as clinical indicators for the diagnosis of this disease.

The effects of polysaccharidical peptides (PSP) on the functions of tumour infiltrating lymphocytes (TILs) in vitro was explored. The results showed that PSP, at the concentration of 37-1200?g/ml, promoted the proliferation of TILs in dose-related manner. Combination of PSP with interleukin-2 (IL-2) enhanced the cytotoxicity of TILs and reduced the dose of IL-2 used for activating TILs. The results suggested that PSP could augment the proliferation and cytotoxicity of TILs in vitro.

Background and purpose:Internal mammary sentinel nodes (IMSNs) lymphoscintigraphy could guide in ?-detecting and removing the IMSNs for the purpose of biopsy during the operation,which is helpful to determine the necessity of postoperative radiotherapy. However,IMSNs imaging rate remains low if using axillary lymph nodes (ALNs) lymphoscintigraphy. This study was to investigate the tracer’s properties and try to improve the IMSNs imaging rate through changing the label procedure. Methods:The boiling time of 99mTC-sulphur colloidal particles was shortened from 3~5 minutes to 2 minutes during the label procedure, then the colloidal particles’ diameter, distribution and stability were observed by Transmission Electron Microscope (TEM), then the IMSNs lymphoscintigraphy was performed. Results:This colloidal tracer’s shape and distribution remained stable for 3 hours, and 90% of the particles had a diameter of 10 nm, the particles tended to aggregate afterwards. 4 hours after labeling, the diameter of particles exceeded 100 nm. IMSNs could be clearly imaged if the tracer was freshly used (within 3 hours after labeling). Conclusion:Within 3 hours after the labeling the unfiltered colloidal tracer with modified procedure, the particle could be used and internal mammary lymph nodes could be imaged more clearly.

ObjectivesTo explore the impact of high body mass index (BMI) on irritable bowel syndrome (IBS) in Chinese adolescents.MethodsThe students were randomly selected from middle school and high school. They completed the epidemiological questionnaire of IBS and had their height, body mass measured.ResultsIn total, 1173 students were recruited, including 700 middle school students and 473 high school students. The incidence of overweight/obesity was 30.52%. The incidence of overweight/obesity was not significantly different between boys (28.40%) and girls (32.65%) (P=0.114), and there was not significantly different between students from middle school (30.57%) and high school (30.44%) (P=0.963). Two hundreds and twenty-one students suffered from IBS and the incidence of IBS was 18.84% with no significant gender difference. The incidence of IBS was significantly higher in students from middle school (13.43%) than those from high school (26.85%) (P<0.001). The incidence of IBS was not statistically significant be-tween overweight/obese students (22.07%) and normal weight students (17.42%) (P=0.061). The distribution of IBS subtypes had no statistical significance between overweight/obese and normal weight students (χ2=0.91,P=0.823). ConclusionsOverweight/obesity and IBS were extremely prevalent in Chinese adolescents, but the correlation be-tween them remains to be confirmed.

Objective To establish the methods of microbial limit test for three kinds of preparations with heavy metals, such asDingxian Pills,Pizhi Lotion andJiawei Huangqin Ointment.Methods According to Chinese Pharmacopoeia 2010, the recovery rates of bacteria, fungus and yeast treated by three preparations were detected. And the methods of testing control bacteria were also validated.Results Culture medium dilution method was proved to be applicable forDingxian Pills. Culture medium dilution method combined with pre-filtration method was proper for Pizhi Lotion. And the extraction method was adopted forJiawei Huangqin Ointment. The recovery rates of these five validation strains reached 70% by appropriate methods. And the same methods were used for validation of the control bacteria.Conclusion The methods of microbial limit test for these three different preparations were established through this study.