2.Evaluation of progress of the appropriate use of drugs by the safety control manager
Koji Osawa ; Mika Matsumoto ; Michiteru Ohtani ; Munetoshi Sugiura ; Katsuyoshi Uchino
Japanese Journal of Drug Informatics 2010;12(1):24-29
[summery]
Our hospital appointed a pharmacist to be safety control manager of drugs. With the aim of promoting an appropriate use of drugs, the safety control manager of drugs ensures the appropriate storage, the expiration, and the use record with control drugs following the business procedure every month. These requirements were confirmed at all divisions of hospital, and then the nonconformity was recorded following the procedure.
The largest number of nonconformity were entry on drugs unseal date and an exceeded the cutoff point of inventory. We couldn’t gain sufficient improvement about an appropriate use of drugs. The causes of this nonconformity were dispersion of drugs at each division and insufficient inventory control of drugs. We attempted to gather and to keep drugs into one group. As a result, the number of nonconformity greatly decreased at all divisions. The amount of money of stock in hospital was decreased by about 20%.
These results suggested that the confirmation of requirements with business procedure by the safety control manager’s rounds of hospital was extremely helpful method with an appropriate use of drugs.
3.Is glue embolization safe and effective for gastrointestinal bleeding?
Shinsaku YATA ; Yasufumi OHUCHI ; Akira ADACHI ; Masayuki ENDO ; Shohei TAKASUGI ; Kazumichi TSUKAMOTO ; Kensuke MATSUMOTO ; Mika KODANI ; Jun MAKISHIMA ; Shinya FUJII
Gastrointestinal Intervention 2018;7(3):158-161
Transcatheter arterial embolization using N-butyl-2-cyanoacrylate (NBCA) for gastrointestinal arterial bleeding enables higher cessation rate and lower recurrent bleeding rate compared with conventional embolic materials including gelatin sponge, metallic coil, and polyvinyl alcohol (PVA) particle. Glue embolization is particularly effective in patients with coagulopathy. Even in the lower gastrointestinal tract, ischemic bowel complications by glue embolization are comparable to other agents. Glue embolization is also effective for arterial esophageal bleeding without any serious ischemic complications although the anatomy of the esophageal artery is complex and varied. For bleeding after abdominal surgery such as pancreaticoduodenectomy or hepatic lobectomy, interventional radiologists should be careful with indicating glue embolization because the presence of fewer collateral vessels can easily result in serious ischemic complications. Modified glue such as Glubran 2 (NBCA associated with methacryloxyfulfolane) can reduce the risk of ischemic complication due to its less thermal reaction, but the outcomes seem unsatisfactory.
Adhesives
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Arteries
;
Cyanoacrylates
;
Embolization, Therapeutic
;
Enbucrilate
;
Gastrointestinal Hemorrhage
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Gelatin
;
Hemorrhage
;
Humans
;
Lower Gastrointestinal Tract
;
Pancreaticoduodenectomy
;
Polyvinyl Alcohol
;
Porifera