At present, there are many problems in the nail-fold microcirculation detection devices, such as huge structure, inconvenience to carry. In addition, due to the patient's body shaking, the video is difficult to keep stable in collecting with the device, which brings great difficulties to the doctor's observation. We develop a small image acquisition device for nail-fold microcirculation based on the principle of SDF imaging principle and liquid lenses technology. An annular lighting device is fixed in front of the optical system, and the overall design of the system is based on the characteristics of human fingers. The device is small, easy to carry and conform to the fingertips. It can focus quickly through a controller. It can also achieve high quality images of the nail-fold microcirculation. This study can promote the usage of nail-fold microcirculation device at the bedside. It's an efficient tool for medical workers to observe the microcirculation of patients.
Humans ; Microcirculation

Chest Pain ; Humans ; Microcirculation

Objective: This study compared the peripapillary retinal nerve fiber layer (pRNFL) microangiographic properties [vessel area density (VAD) and blood flux index (BFI)] of unilateral open-angle glaucomatous eyes to contralateral eyes-at-risk, and to eyes of healthy age- and sex-matched subjects. Methods: This was a single-center, case-control study of Filipinos diagnosed with unilateral primary openangle glaucoma (POAG) or normal-tension glaucoma (NTG). Mean overall and quadrantal VAD and BFI of the three groups were measured with optical coherence tomography- angiography (OCT-A). Area under the receiver operating characteristic (AROC) was used to measure diagnostic ability. Results: Twenty-two (22) glaucomatous subjects (15 POAG and 7 NTG eyes), 22 contralateral eyes-at-risk, and 22 normal eyes from age- and sex-matched control subjects completed the study. Eyes with glaucoma showed lower mean overall VAD (40%) and BFI (0.37) compared to eyes-at-risk (44.4% and 0.42, respectively; p <0.001) and control eyes (45.6% and 0.44, respectively; p <0.001). Mean VAD and BFI values of eyes-at-risk and control groups did not significantly differ from each other. Overall pRNFL thickness showed highest diagnostic accuracy for glaucoma (AROC = 0.97), followed by VAD (0.94), and BFI (0.88) (p=0.46). Conclusion VAD and BFI were significantly diminished in unilateral open-angle glaucoma, suggesting that the utility of OCT-A in the detection of glaucoma is comparable to pRNFL thickness.
Microcirculation ; Glaucoma ; Angiography

Humans ; Microcirculation ; Sepsis ; physiopathology

Coronary Vessels ; Humans ; Microcirculation

Contrast echocardiography is an important technique that .,/ can be used to examine the cardiac cavity, vascular tructure, intracardiac shunt, and myocardial microcirculation. uses gasfilled microbubbles and various imaging techiques. The properties of microbubbles and their interaction Ath ultrasound are important in ultrasoundenhanced conast imaging. This article will describe microbubbie physics id new ultrasound techniques that are necessary to under--and the basics of contrast echocardiography. The utility of )ntrast echocardiography in various clinical scenarios will be so described.
Echocardiography* ; Microbubbles ; Microcirculation ; Myocardium ; Ultrasonography

No abstract available.
Fingers* ; Microcirculation* ; Smoke* ; Smoking* ; Toes*

No abstract available.
Cheek* ; Microcirculation* ; Skin* ; Smoke* ; Smoking*

OBJECTIVE: To explore the mechanism of smoking that promotes chronic periodontitis from the perspective of gingival microcirculation. METHODS: In experiment one, upper anterior teeth (n=102) from smokers with chronic periodontitis (Group A), nonsmokers with chronic periodontitis (Group B), and nonsmokers with healthy periodontal conditions (Group C) were selected to undergo gingival blood flow (GBF) through laser doppler flowmetry. In experiment two, the tissues obtained from gums during periodontal flap surgery were divided into smoking (Group A') and nonsmoking (Group B') groups, and the gingival tissue obtained from periodontal healthy nonsmokers treated with crown lengthening surgery or impacted wisdom tooth extraction served as the control group (Group C'). The microvessels density (MVD) of the gingival tissue from the three groups was determined in the tissue sections. SPSS 22.0 was used for statistical analysis. RESULTS: Compared with group C, GBF of all teeth increased in group B, and there were significant differences among 12, 21 and 23 teeth. MVD significantly differed between Group B' and C' (P<0.05), but they did not significantly differ between Group A' and B'. CONCLUSIONS Periodontitis can increase GBF and MVD, but smoking does not cause significant changes. However, the mechanism by which smoking promotes the occurrence and development of chronic periodontitis by influencing gingival microcirculation has not been discussed in this research.
Chronic Periodontitis ; Humans ; Microcirculation ; Smoking

Altitude ; China ; Ethnic Groups ; Hemoglobins ; Humans ; Microcirculation