Butyrate is a short-chain fatty acid produced during fermentation of fibers and other substrates in the gastrointestinal tract. A recent study has shown that elevation of butyrate availability by dietary supplementation exerts favorable effects on glucose metabolism. However, it remains unclear whether butyrate intake affects insulin-sensitive glucose transporter (GLUT-4) protein content in skeletal muscle, which has been shown to be closely related to muscle glucose transport capacity and whole-body insulin sensitivity. The purpose of this study was therefore to examine the effects of dietary intake of butyrate on muscle GLUT-4 protein content and whole-body insulin sensitivity in rats. Seven-week-old male Sprague-Dawley rats were placed on a sodium butyrate diet (SB) or standard chow diet (CON) for 2 wks. Sodium butyrate was incorporated into the standard chow diet at 5 % wt/wt. After the 2-wk dietary intervention, insulin tolerance test (ITT) was performed to evaluate whole-body insulin sensitivity. GLUT-4 protein contents in soleus and epitrochlearis muscles were determined by western blot analysis. There were no significant differences in body weight, food intake and intra-abdominal fat weight between the SB and CON groups. GLUT-4 protein contents in soleus and epitrochlearis muscle were significantly lower in the SB than CON group. The SB group had less reduction in glycemia than did the CON group during ITT. These results suggest that dietary intake of sodium butyrate may decrease muscle GLUT-4 protein content and impair whole-body insulin sensitivity in rats.

A 66-year-old man suddenly fell into a state of shock on his way back to his room after emergency coronary angiography and intracoronary thrombolysis for acute myocardial infarction. Both echocardiography and pericardiocentesis suggeted a diagnosis of cardiac rupture. The patient was transferred to an operating room with a percutaneous cardiopulmonary support system (PCPS) and intraaortic balloon pumping. Following thoracotomy and release of cardiac tamponade, blow out rupture of the left ventricular free wall was detected. The rupture was repaired using triple mattress sutures by reinforcing with felt pledgets. An infarctectomy was not added and cardiopulmonary bypass was not used. Postoperative recovery of cardiac function was satisfactory and the left ventricular ejection fraction after 2 months was 35%. PCPS and consecutive surgical therapy are effective for the treatment of blow out rupture of the left ventricular free wall.

Aim:The usefulness of high-density barium, which was made to 150w/v% (MIX150), was examined to obtain better radiographs of the intestines. Methods: “MIX150” was compared with existing pharmaceutical “BAM100” to evaluate x-ray images (barium adhesion, dryness evaluation). MIX150 was used in 232 patients (mean age 56 years), while BAM 100 in 210 patients (mean age 55 years). Results: In terms of adhesion, MIX150 was excellent in the the cecum significantly and in dryness evaluation, in the entire region of the colon. Conclusion: High-density barium (150w/v%) was useful for enhancing the quality of radiographic images.
physical density ; Euphoric mood ; Roentgen Rays ; Barium ; Lower case vee