The objectives of this study were to investigate the effects of Hericium erinaceum (Yamabusitake) and Grifola frondosa (Maiteke) on the proliferation for EL4-tumor and immunoregulatory function by flow cytometory.
It was found that Yamabushitake and Maitake tend to inhibit the proliferation of EL4-tumor individually. In the flow cytometory analysis, Maitake-treatment showed the preserve effect against the depression effect by bearing EL4-tumor on cytotoxic T cell and NK-cell from spleen cell. This effect was shown more clear in the group of mixture Yamabusitake and Maitake.

A 67-year-old man was considered a candidtate for CABG because coronary angiogram showed obstruction segment 6 and stenoses of segments 9 and 12. He underwent emergency CABG due to acute myocardial infarction (AMI) with cardiogenic shock caused by hemorrhage from a gastric ulcer. Because of hypoxia due to pulmonary edema and acute renal failure an intraaortic baloon was inserted. He had a history of cerebrovascular stroke. Although coronary angiogram revealed multiple vessel disease, we performed off-pump coronary artery bypass (saphenous vein graft-left anterior descending artery) for salvage, because cardiopulmonary bypass was considered very risky and further systemic heparinization might be fatal. He has returned to his job, and is now free from angina. As AMI with cardiogenic shock is often caused by a lesion in the LAD, CABG without cardiopulmonary bypass may be an effective technique in certain selected patients.

A 76-year-old man with multivessel disease in the coronary artery and abdominal aortic aneurysm, including the bilateral common iliac artery aneurysms, underwent off-pump coronary artery bypass (OPCAB) combined with repair of the aneurysms. We were able to perform three coronary artery bypass graftings (left internal thoracic artery-left anterior descending artery, saphenous vein graft-diagonal branch, and saphenous vein graft-atrio-ventricular branch) using an Octopus 2 and a“Lima”suture technique without cardiopulmonary bypass. The postoperative course was uneventful. All grafts were patent on postoperative angiograms. OPCAB combined with repair of abdominal aortic aneurysm was useful for the high-risk patient.