Esthesioneuroblastoma is one of the most uncommon nasal malignancies which is characterized by low incidence and high misdiagnosis rate.The only prognosis factor is the metastasis on lymph node of neck.Its clinical symptoms are associated with tumor infiltrating extent.Pathological diagnosis is the “gold standard” on esthesioneuroblastoma,and the Kadish staging based on the image is the most important staging standard.The traditional operation therapy mode has been replaced by the combined method of operation and radiotherapy,with the adjunctive therapy of chemotherapy.

At the 2024 Annual Meeting of the American Society of Clinical Oncology (ASCO), multiple research achievements in the field of colorectal cancer were announced. This article summarizes and interprets the research results related to colorectal cancer from the perspectives of local treatment progress, immunotherapy progress, targeted therapy, neoadjuvant therapy and surgery, and explores the hot spots, problems, and future directions of colorectal cancer treatment.