1.Environmental hygiene monitoring and management in blood purification center
The Journal of Practical Medicine 2015;31(16):2763-2765
Objective To analyze themonitoring results of environmental hygiene inthe Blood Purification-Center and explore the management. Methods Hospitalinfection control personnel carried on the environmental hygiene monitoring in the blood purification center from 2010 January 2010 to December 2014. A total of 656 sampleswere examined , with monitoring covering airindex , surface of objects , hands of medical staffs and dialysis water. The infections from temporarydouble lumen catheteration were analyzed during the period. Results Of the 656 examinedsamples, 613 were qualified, with the overall pass rate of 96.4%. All the monitoring samples basi-cally achieved the qualified standard, with zero detection rate of the pathogen. The temporarydouble lumen catheterinfection rate was decreased from 8.6% to 3.4% during the period andthe difference was statistically sig-nificant between 2014 and 2010 (χ2 = 7.73, P < 0.01). Conclusion Strengthening the environmental hygiene monitoring may help increase the dialysis treatment and nursing work , decrease the infection rate of temporary dou-ble lumen catheter in hemodialysis patients and improve their quality of life.
2.Determination of Cinnamaldehyde in Guizhi Fuling Drop Pills by RP - HPLC
Xiaohong HUANG ; Changqing ZHANG ; Miaofen CHEN
China Pharmacy 2001;0(12):-
OBJECTIVE:To determine the content of cinnamaldehyde in Guizhi fuling drop pills by RP - HPLC. METHODS:The determination was performed on Symmetry C_(18)(150 mm?4.6 mm,4?m) with the mobile phase consisted of acetonitrile 0.1%phosphoric acid solution(21:79) at a flow rate of 1.0 mL?min~(-1).The detection wavelength was set at 284 nm.RESULTS:The linear range of cinnamaldehyde was 4~40?g?mL~(-1)(r =0.999 8) with an average recovery of 99.39% (RSD = 1.22,n = 9).CONCLUSION:The established method is simple,accurate,precise and applicable for the quality control of Guizhi fuling drop pills.
3.Serotype distribution and antimicrobial susceptibility of 72 strains of Salmonella
Ting ZHANG ; Zhiqin GUO ; Fengping WANG ; Lijuan LI ; Miaofen ZHANG
Chinese Journal of Infection and Chemotherapy 2014;(6):532-534
Objective To understand the serotype distribution ,prevalence and antimicrobial susceptibility of Salmonella strains isolatd from diarrhea patients in Dongguan ,Guangdong Province .These data may be useful for disease control and prevention and clinical treatment .Methods From April to December in 2013 ,we collected 1 150 stool specimens from diarrhea patients . Salmonella strains were cultured by using Salmonella selenite brilliant green sulfa enrichment broth and selective chromogenic plates .Antimicrobial susceptibility was tested by ATB microbial identification and drug susceptibility system .Results A total of 72 strains of Salmonella were identified including 21 serotypes .The detection rate was 6 .3% (72/1 150) .Most of the strains were Salmonellatyphimurium (22/72 ,30 .5% )and Salmonellaenteritis (16/72 ,22 .2% ).Forty‐two (58 .3% )of the strains were isolated from the patients under one year of age ,12 (16 .7% ) strains from the patients of 3‐10 years of age ,and 18 (25 .0% ) strains from the patients of at least 20 years old .The results of antimicrobial susceptibility testing showed that 50 .0% of the strains were resistant to piperacillin and 48 .6% resistant to ticarcillin .Conclusions The prevalence of Salmonella typhimurium is the highest in local Salmonella‐associated diarrhea patients ,followed by Salmonella enteritis .Most of the Salmonella diarrhea occurred in the patients under one year of age .Clinicians should strengthen the monitoring of Salmonella in patients with diarrhea , especially in infants and young children , for early detection and treatment so as to reduce complications .