The influence of individual vitamin on immunity has been described before. In this report, the comprehensive effect of vitamin A, E, riboflavin, pyridoxine and folic acid on the immune response was studied in the BALB/C mice. Animals were divided into five groups:control group, one-third requirement group, double requirement group, triple requirement group and restored group (feeding insufficient diet for six weeks, and then normal diet for another two weeks). The results showed that the percentages of the peripheral blood T cell, Tu cell were diminished significantly in the deficient group in comparison to controls, on the contrast, those in double and triple requirement groups increased obviously, and also did the restored group supplemented normally but no difference in the percentage of Ty in all groups. The study also showed a positive correlation between the relative, absolute thymic weight and the percentage of the peripheral blood T cell. The changes stated above of the peripheral blood T cell and its sub-populations are partially owing to the abnormality of the thymic tissue, but the distribution of lymphocyte shouldn't be neglected. The study found the plaque forming cells (PFC) of spleen, aud the ratio of 3H-thymidine incorporating into splenic lymphocyte after exposure to ConA, PHA and LPS in vitro were increased significantly in double and triple requirement groups; but with the vitamin complex under supply, the former was requced significantly, the latter was comparable to the controls. The PFC increased markedly and no difference with the double group after insufficient animals fed normal diet for two weeks. It is therefore not surprising that the vitamin complex plays a special role in the differentiation and maturation of PFC. According to the study, the vitamin complex may influence the growth of lymphoid tissue, the differentiation and maturation of immunocompetent cells and functional manifestation by mainly affecting the contents of cAMP, cGMP of lymphocyte, and the metabolism of nucleic acid and protein.

Objective:Comparing the expression of tumor necrosis factor receptor 1 (TNFR1) in decidua tissue and soluble tumor necrosis factor receptor 1(sTNFR1) in serum of normal pregnancy and spontaneous abortion mice to probe the relationship between TNFR1 and unexplained spontaneous abortion.Methods:The abortion-prone CBA?DBA/2 mating was established as the model of spontaneous abortion and nonabortion-prone CBA?BALB/c matings were used as the model of normal pregnancy.Immunohistochemistry method(SABC) was employed to detect the expression of TNFR1 in decidua tissue at the day 9 of gestation.The level of sTNFR1 in serum at the same time was determined by ABC-ELISA.Results:Compared with normal pregnancy model,the expression of TNFR1 in decidua tissue of spontaneous abortion was significantly increased (P

Objective To analyze and compare the HBV DNA contents in serum and breast milk after injection of hepatitis B im‐munoglobulin (HBIG) in different periods of pregnant and lying‐in women to provide the experimental basis for blocking the mater‐nal‐neonatal transmission(PMTCT) and breast feeding scheme .Methods 140 pregnant women carrying hepatitis B virus with HB‐sAg(+ ) by antenatal examination in the obstetric outpatient department of our hospital from June 2012 to June 2014 were selected and divided into the research group and the control group according to the voluntary and secretive principle .Among them ,75 cases in the research group were intramuscularly injected by high titer HBIG 200 U at 28 ,32 ,36 weeks of pregnancy ,while 65 cases in the control group were injected by HBIG at the end of pregnancy due to different causes .Serum HBV‐DNA content before injection and before delivery was detected in the two groups ,and which in neonatal serum and breast milk within 3-5 d also detected .The differences and correlation between the two groups were analyzed .Results The HBV‐DNA content <500 copies/mL ,500-1 × 106 copies/mL ,>1 × 106 copies/mL before HBIG injection in the research group were 28 cases ,17 cases ,30 cases respectively ,which before delivery were 35 cases ,20 cases ,20 cases respectively ;which in antenatal twice detection in the control group were 19 cases , 21 cases ,25 cases and 20 cases ,17 cases ,28 cases respectively ;neonatal serum HBV‐DNA positive in the research group and control group had 1 case(5 .3% ) and 5 cases (7 .7% ) respectively ;the breast milk HBV‐DNA positive in the two groups had 3 cases(4% )/and 8 cases(12 .3% ) respectively .Conclusion HBIG injection at late pregnancy in the pregnant women carrying HBV could influ‐ence the HBV replication ,thus reduces the probability of neonatal intrauterine infection ,at the same time reduces the HBV‐DNA positive rate of postpartum breast milk .

The first case of Hurthle cell tumor of the thyroid gland(HCT) was described in the literature a century ago. Since then, researches of HCT have been progressing from cellular to molecular level. We reviewed the literatures about HCT researching, with emphasis on differentiated diagnosis of benign and malignant HCT.

PURPOSE: The purpose of this study was to identify premorbid personality, depression and disturbing behaviors to provide information for developing nursing interventions for the pre-demented and mild demented elderly living as residents of their community. METHOD: The survey was conducted through direct interviews using a structured questionnaire in J city. Among the subjects contacted, 89 made appropriate replies to the survey. RESULT: The subjects' disturbing behaviors were significantly related to premorbid personality and depression. The predictors to disturbing behaviors of the pre-demented elderly were sex, extroversion, neuroticism and conscientiousness. The predictors to disturbing behaviors of the mild demented elderly were agreeableness, depression, sex, conscientiousness, and extroversion. CONCLUSION: In conclusion, disturbing behaviors of pre-demented elderly and mild demented elderly are affected not only by their premorbid personality but also by their depression. Therefore, it is necessary to encourage and respond to them with understanding their disturbing, behaviors in relation to their premorbid personality. In addition. it is important to maintain positive emotion in order to reduce their disturbing behaviors.
Aged* ; Dementia ; Depression* ; Extraversion (Psychology) ; Humans ; Nursing ; Surveys and Questionnaires

Objective To summarize the experience of nursing cancer patients with anal fistula treated with blood stem cells transplantation (BSCT). Method 8 critical cancer patients with anal fistula treated with BSCT from August 2013 to November 2014 were intervened by nursing measures such as prevention of constipation and diarrhea , protecting the anus from infection and health education . Results Two patients of them contracted with mild crissum infection , 1 moderate , 0 severe . With the pertinent nursing intervention , no serious complications occurred . The hospital stay was 20~30 d , with an average of ( 24 . 75 ± 2 . 30 ) . Conclusion The nursing measures including preventing constipation and diarrhea, keeping the anus from infection and health education can be effective in avoiding anal fistula infection and its related complications and reducing patients′pain , which are worth clinical promotion .

Objective To investigate the correlation between serum adiponectin level and severity of coronary artery disease.Methods We measured the serum concentrations of adiponectin in 135 patients whom had received CAG.The severity of coronary artery lesion was evaluated by Gensini score,the number of stenosis vessel and clinical manifestation.Results The serum concentrations of adiponectin in Gensini score 0 group(74.53?30.76 ng/mL)and score 40 group(28.96?11.87 ng/mL)(P40 group were lower than those in score 20-40 group(P

This paper analyze the dynamic observation results ofCD4+ and CD8+ T lymph cell of13 cases HIV/AIDS patients, who have survived for more than ten years.The analysis show that long term Chinese medicine intervention have effect in increasing and maintaining CD4+ T lymph cell, and activating or adjusting CD8+ lymph cell.Chinese medicine also has the effect in delaying the progression ofAIDS and prolonging longevity.

Objective To study the imageological findings and the evolution of pulmonary alveolar microlithiasis(PAM). Methods The clinical and imageological information of 3 siblings suffering from PAM were collected, and their imageological findings and changes in follow-up plain radiographs were analyzed retrospectively. Results On chest radiographs, the typical “sandstorm” pattern was shown in all 3 cases. The severity and extent of microliths and interstitial fibrosis were increased with age and clinical course by comparing with the radiographs 24 years ago. On conventional CT, bilateral diffuse micronodules in parenchyma were demonstrated with pulmonary window in 3 cases, concentrating in the subpleural zones of middle and lower lung fields and the areas around bronchovascular bundles. All were associated with various degrees of fibrosis. The nodules and calcifications were visible in both lungs with mediastinal window, forming so-called flame sign and white line sign in the concentrated areas. The extents and degrees of the microliths, small cysts and interstitial fibrosis were revealed more clearly and truly on HRCT. MRI showed diffusely increased signal intensity on T 1WI and lower signal intensity on T 2WI in both lung fields. Conclusion The chest radiograph was still an initial modality in detecting the disease. CT could comprehensively reveal the pathological status of the PAM and played a decisive role in the diagnosis and differential diagnosis. MRI had only limited value in evaluating the condition.

Objective To assess the effect of interleukin 8 and cortisol on the onset of idiopathic preterm labor (PL) Methods In 35 women with preterm labor and 17 controls, maternal serum and urine samples were collected. Interleukin 8 concentration was measured by enzyme linked immunosorbant assay, serum cortisol level was measured by radioimmunoassay Results The concentration of interleukin 8 in maternal serum and urine and cortisol in serum were significantly higher in PL group than those in the control [(0 26?0 13) ?g/L vs (0 16?0 08) ?g/L, (0 16?0 15)?10 -2 g/mol Cr vs (0 04?0 02)?10 -2 g/mol Cr, (765 83?408 55) ?g/L vs (512 41?142 65) ?g/L; P