Objective To explore the prognostic factors in patients with acute respiratory failure due to chronic obstructive pulmonary disease (COPD) in EICU. Method Clinical data of 39 patients admitted to EICU from May 2005 to May 2007 were retrospectivley analyzed. Results In death group, the pulmonary artery pressure (PAP) ,creatinine (Cr) ,APACHE-Ⅱ score, and APACHE-Ⅲ score were increased (P < 0. 05) and ICU stays were prolonged (P < 0.05) ; Respiratory rate (RR) and Glasgow coma score (GCS) were decreased (P < 0.05). Conclusion PAP, Cr, APACHE-Ⅱ score,APACHE-Ⅲ score,RR and GCS predict the prognosis of the patients with acute respiratory failure due to chronic obstructive pulmonary disease.

The advantages of non-contact medical monitoring radar were introduced compared with the traditional medical monitoring devices. The state of art of three kinds of typical medical monitoring radar schemes over the past decade was reviewed. Researches on breathing and heartbeat signal extraction, isolation and clutter suppression algorithms were summarized. The advantages and disadvantages of these algorithms were also pointed out. The prospects of non-contact medical monitoring radar were explored finally.

Objective To evaluate the abilities and thresholds of stroke volume variation (SVV) and pleth variability index (PVI) in predicting fluid responsiveness during increased intra-abdominal pressure.Methods 28 patients undergoing laparoscopy-assisted radical gastrectomy were selected.PV1 was continuously displayed by the Masimo.Radical 7.All patients were also monitored with Vigileo/FloTrac system.Haemodynamic data such as MAP,HR,SVI,SVV,PI,PVI and C VP were recorded before and after volume expansion(HES 6％,7ml/kg).Fluid responsiveness was defined as an increase in SVI≥ 15％ (△ SVI ≥ 15).Results The SVV threshold of 9.5％ before volume expansion was able to diserimihate the responders from the non-responders with a sensitivity of 100％,and a specificity of 63.6％.The threshold for PVI was 14.0％,the sensitivity of 100％ and specificity of 81.8％ were obtained.There was no significant difference between the area under the receiver operating characteristics (ROC) curves of SVV and PVI(0.981,0.939,respectively),and there was significant correlation between the baseline SVV and the baseline PVI(r =0.740,P ＜ 0.01).Conclusion SVV and PVI can predict fluid responsiveness accurately during increased intra-abdominal pressure,the baseline SVV is correlated well with baseline PVI,and the ability of SVV and PVI in predicting fluid responsiveness is similar.

BACKGROUND:The cytokine has an effect of immunoregulation and immediate induction in the reconstruction of periodontal tissue. At present, the role and mechanism of hepatocyte growth factor involving the reconstruction of periodontal tissue under orthodontic force are stil unclear.
OBJECTIVE:To explore the mechanism underlying hepatocyte growth factor in the tooth movement and periodontal tissues remodeling under the inflammation periodontal tissue condition.
METHODS:Thirty Sprague-Dawley rats, aged 8 weeks, were used to establish periodontitis model. The obtained model was randomly divided into two groups:inflammatory control group and inflammatory force group. In the force group, rats were treated with the fixed orthodontic appliance by 50 g forces in the maxil ary first molars. After 1, 3, 5, 7 and 14 days of tooth movement, five rats were sacrificed respectively. Hematoxylin-eosin staining and immunohistochemistry methods were used to analyze the expression and distribution of hepatocyte growth factor in the periodontium for rats at different tooth movement stages.
RESULTS AND CONCLUSION:Hematoxylin-eosin staining results showed that, remodeling of periodontal tissues existed in al groups. (2) The immunohistochemical results showed that hepatocyte growth factor had positive expression in periodontal tissue, and the distribution was even in the control group. In the force group, hepatocyte growth factor expression was increased and reached the peak on day 5, then began to decline. Osteoblast, fibroblast and osteoclast were strongly expressed. The findings indicate that, hepatocyte growth factor is involved in the periodontal tissues remodeling under orthodontic force, and inflammation can increase the expression of hepatocyte growth factor in periodontal tissue.

Medicine is a practical application subject,so medical students should conduct numerous clinical practice to improve operation skills and clinical diagnosis ability The ability of clinical practice is one of most important indicators to evaluate medical education quality.In recent years,medical students have been affected by many kinds of adverse factors,such as new doctor-patient relationship,the medical reform and employment pressure and so on.All these adverse factors will bring a great challenge to the dental clinical teaching.In the new medical situation we need urgently to solve the problems to guide students to improve clinical practice ability and cultivate qualified dental professionals

Objective To investigate the expression of Survivin gene and the relationship between Survivin and genesis and development of cervical cancer. Methods The expression of Survivin gene in tissues of 40 patients with cervical cancer, 38 patients with cervical hyperplasia and 10 cases of normal cervical were detected by immunohistochemical SP method, and the relationships between Survivin and the clinical pathological factors were analyzed. Results The expression positive rate of Survivin in cervical cancer tissues (60 %) was significantly higher than that in cervical hyperplasia and normal cervical tissues (42.1 % and 0, respectively), and their differences were statistically significant (P < 0.05). The positive expression rate of Survivin was related with histological grade and the clinical stages of cervical cancer.Conclusion Survivin is related to the genesis and development of cervical cancer.

Objective The facial soft tissue features were studied in Urumqi adolescent with skeletal Ⅱ malocclusion by using a polar coordinate system. Methods Sixty samples of Urumqi adolescent with skeletal Ⅱ malocclusion were selected, each one underwent cephalometrics analysis and 32 cephalometric parameters from the samples were measured. The mean and standard deviations of each measurement were compared by statistical analysis (t-test). Results Polar distance in male was larger than female, showing significant difference between male and female. Po-Ns/Po-Li, Po-Ns/Po-Bs, Po-Ns/PoPgs, Po-Ns/Po-Gns, and Po-Ns/Po-Mes showed significant difference between male and female. Polar angles in female were larger than male, with a significant difference between male and female.Conclusion Statisticalstudies on features of facial soft tissue show significant differences between male and female. The polar coordinate analysis system is a good index to study the growth magnititude and direction of facial soft tissue during growth and development or before treatment and after treatment.

OBJECTIVE:To summarizethe application of polypropylene repair material in treating inguinal hernia.METHODS:Papers regarding polypropylene repair material in treating inguinal hernia published in VIP data between January 1998 and October 2009 were researched using key words of "polypropylene,inguinal hernia,and complication".Inclusion criteria Repairing inguinal hernia using polypropylene materials.Experimental results concerning related complications.Exclusion criteria:repetitive study and relatively old literature.A total of 17 documents were included in this study.RESULTS:Organic polymeric materials were clinical utilized in repairing inguinal hernia at the end of 1950s.The polypropylene patch was knitted by slngle fiber or multi-strands fibers of polypropylene,and exhibited single layer network structures,which is preferred material for repairing abdominal-wall defect.Compared with other unabsorble materials,the polypropylene patch had following advantage:obviously stimulating fibroplasias; easy permeated by fibrous tissues and embedded into tissues; maintaining highly tensile strength following implantation; and relative low cost.Few material-related complications occurred following repairing,mainly presented with infection,serofiuid swelling,ankylenteron,intestinal leakage,material displacement,as well as material shrinkage.CONCLUSION:Polypropylene material is an ideal repair material due to good histocompatibility,few rejections,and anti-infection capability.It leads to easy operation,small trauma,fast recovery and few complications in repairing defects.

The neuromechanism of language function recovery in patients with aphasia after stroke is still unclear. It is supported that the language function of aphasia after extensive damage of left hemisphere mainly recovered through activating the right hemisphere of ho-mologous regions to improve the function of speech. Melodic intonation therapy (MIT) can be achieved by melody tone and left hand clap to activate the right hemisphere of the frontal temporal lobe, which is particularly applicable to improve language function of non-fluent aphasia patients with large left hemisphere lesion. Non-invasive brain stimulation techniques (NBS) changes brain activity through stimulat-ing affected or contralateral side, which has been used to facilitate language functional recovery after stroke. Excitatory transcranial stimula-tion on the right hemisphere homology combined with melodic intonation therapy can promote language recovery of patients with extensive damage of left hemisphere after stroke. It is valuable to combine traditional speech training with MIT and NBS to activate related language functional areas to maximum improvement of language recovery after stroke.

Objective:To examine the effects of acute or chronic administration of 7-nitro indazole (7-NI) on the MAC of sevoflurane and cerebellar cGMP levels in mice. Method:In acute experiment,sevoflurane MAC was determined in mice after 7-NI 120mg/kg, 180mg/kg or 120mg/kg plus L-arginine 600mg/kg was given intraperitoneally. During chronic experiment, MAC was measured on 1st, 4th and 7th day during week-long gavage feeding of 7-NI. The levels of cerebellar cGMP also were measured after acute and chronic administration of 7-NI. Result:Acute administration of 7-NI 120mg/kg decreased sevoflurane MAC by about 20% and cerebellar cGMP level by 96%. 7-NI 180mg/kg did decrease MAC not more than 7-NI 120mg/kg. No significant reduction of MAC was observed in mice treated by intraperitoneal 7-NI 120mg/kg+L-arginine 600mg/kg. In chronic experiment,sevoflurane MAC and cerebellar cGMP were decreased significantly on 1st 4th and 7th day to the similar extend, with 15%-20% reduction in MAC and 46%-60% in cGMP levels. Conclusion:Acute and chronic selective inhibition of nNOS decreases sevoflurane MAC and cerebellar cGMP levels in mice. The maximal reduction (only about 20%) of MAC can be obtained when cGMP levesl are decreased about 50% and further inhibition of generation of cGMP does not produce more enhancement to the potency of sevoflurane anesthesia. No compensatory mechanism for the inhibition of L-Arg-NO-cGMP pathway appears during week-long treatment with 7-NI.