Objective To explore the rules of skin metastasis so as to make correct diagnoses. Methods The clinical and pathological data of 108 cases with skin metastasis were collected, reviewed and analyzed.Results There were 65 male and 43 female among those 108 cases, with an average age of 49 8 years. The metastasis occurring regions in turn were abdomen, chest, shoulder-back, waist-glutea, head-neck, extremities, perineum, vulva and whole body. The average time of the appearance from skin mass to diagnosis was 3 5 months. Skin metastasis occurred at mean 16 2 months after diagnosis of primary tumor. The commonest sites of original tumor were lung, large intestine, stomach, unknown primary site and esophagus in male,breast, large intestine, ovary, lung and unknown primary site in female respectively.Conclusions In consistent with cancer morbidity,the cancer with high incidence has a high skin metastasis rate. Skin metastasis often appeared on the skin near primary lesion. It should be suspected to skin metastasis,if skin nodule appears on patient with cancer history.

Objective To investigate the stigma in the public about the patients with depression and diabetes.Methods The stigma situation of the publics (workers,peasants,students,intellectuals and others,collect 300 respectively) were assessed for the patients with depression and diabetes with the Struening Belittle Scale.1500 questionnaires were distributed and 1421 effectual questionnaires were retrieved.Results ① A comprehensive compare of public stigma between depression and diabetes showed that about 89.0％ of the public with stigma and 11.0％ of the public without stigma for the patients with depression,about 32.0％ of the public with stigma and 68.0％ of the public without stigma for the patients with diabetes.There were significant differences in frequency of public stigma for two diseases (x2 =744.906,P ＜ 0.01).②There were significant differences in the total scores((52.8 ± 12.4) vs(32.4 ± 13.6),t =5.328,P ＜ 0.01) and subscale scores of the Stmening Belittle Scale (Patient Belittle Scale:(26.5 ± 8.6) vs (12.4 ± 5.6),t =3.276,P ＜ 0.01 ; Family Belittle Scale:(22.8 ±6.4) vs(9.4 ± 5.2),t =2.988,P＜ 0.01) of the public for the patients with depression and diabetes.Conclusion There is serious stigma in the public for patients with depression.It is more serious and extensive than that for patients with diabetes.

OBJECTIVE:To investigate chemotherapeutic efficacy and safety of Paclitaxel combined with lobaplatin by inter-ventional embolization for cervical cancer. METHODS:Totally 68 cases of cervical cancer patients selected from our hospital dur-ing May 2010-Mar. 2014 were divided into control group and observation group according to therapy plan,with 34 cases in each group. Control group was given Paclitaxel liposome for injection 175 mg/m2 added into 5% Glucose injection 250 mL,ivgtt+Loba-platin for injection 80 mg/m2 added into 5% Glucose injection 250 mL,ivgtt. Observation group was given Paclitaxel liposome for injection 175 mg/m2+Lobaplatin for injection 80 mg/m2+5% Glucose injection 10 mL via percutaneous catheter after selecting uter-ine artery and tumor vessel by arterial catheterization arteriography,gelfoam embolization. Both groups were treated in the first day of every treatment course,21 d as a treatment course,for 3 courses. Clinical efficacies were observed in 2 groups as well as the levels of T lymphocyte subsets(CD4+,CD8+,CD4+/CD8+)before and after treatment. The occurrence of ADR during treatment,lo-cal recurrence and metastasis after 2 years,and survival situation were recorded. RESULTS:The total response rate of observatio group(85.29%)was significantly higher than that of control group(61.76%),with statistical significance(P<0.05). Before treat-ment,there was no statistical significance in the levels of CD4+,CD8+ or CD4+/CD8+ between 2 groups (P>0.05). After treat-ment,CD4+and CD4+/CD8+of 2 groups were increased significantly,while CD8+was decreased significantly;above indexes of ob-servation group were improved significantly compared to control group,with statistical significance (P<0.05). The survival time of observation group [(22.58±0.61)months] was significantly longer than that of control group [(17.61±1.32)months],and 2-year survival rate(70.59%)was significantly higher than control group(47.06%),with statistical significance(P<0.05). There were no statistical significance in incidence of disease control,incidence of total ADR and incidence of local recurrence and metastasis between 2 groups (P>0.05). CONCLUSIONS:Paclitaxel combined with lobaplatin by interventional embolization show definite chemotherapeutic efficacy for cervical cancer,and can improve the levels of T lymphocyte subset with good safety.

Objective To analyze the status of biobanks in public hospitals in Shanghai.Methods A questionnaire survey on biobanks was conducted in 9 representative public hospitals in Shanghai.Results The management system of hospital biobanks in Shanghai was basically shaped,but the human resources and financial inputs were in shortage,and some management and regulations were not in place yet.Conclusions The biobanks of public hospitals need more inputs,improvement,and standardized management.