1.Overview of traditional Chinese medicine quality evaluation method based on overall research.
Hua JIANG ; Yuan GAO ; Jing-ming YANG ; Xiang-cai MENG
China Journal of Chinese Materia Medica 2015;40(6):1027-1031
The establishment of quality evaluation of traditional Chinese medicine system that not only accords with Chinese medicine function characteristics but also is recognized as international medical circles, is an arduous task in urgent need of solving the current modernization of traditional Chinese medicine in the process of internationalization. It is difficult to evaluate atraditional Chinese medicine by detection of single active components in traditional Chinesemedicinewiththe western medicine quality controlmethod due to the overall effects of traditional Chinese drugs, the components of the overall diversity, targets, and the complexity of the interaction between components of unpredictable make the Long-term since, domestic and foreign scholars continue to explore and put forward a series of quality evaluation of traditional Chinese medicine to promote the development of traditional Chinese medicine. This article summarized the related academic ideas and developments to, providea new thought and perspective for the quality control of traditional Chinese medicine.
Drug Evaluation
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methods
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standards
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Drugs, Chinese Herbal
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chemistry
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Humans
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Medicine, Chinese Traditional
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standards
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Quality Control
2.Efficiency of Cleaning Curets by Different Methods and Their Comparison
Jian LIU ; Hua WANG ; Yuan ZHANG ; Yuan XIN ; Xiaohong LI ; Huanxin MENG
Chinese Journal of Nosocomiology 2006;0(12):-
OBJECTIVE To compare the efficiency of cleaning curets by different methods.METHODS After clinical use,curets were randomly divided into 4 groups according to the different cleaning methods: groups A,immersing+enzyme+ultrasonic;B,brushing+enzyme+ultrasonic;C,enzyme+ultrasonic;D,immersing+enzyme+brushing.RESULTS The efficiency of cleaning curets was significantly higher in groups A(82.3%),B(86.5%) and D(83.7%) compared with group C(75.9%,P
3.Effect of Acupuncture on Prognosis and Immune Function of Sepsis Patients.
Qiu-sheng XIAO ; Ming-yuan MA ; Xing-sheng ZHANG ; Meng-hua DENG ; Zhul Yang YAN
Chinese Journal of Integrated Traditional and Western Medicine 2015;35(7):783-786
OBJECTIVETo study the effect of acupuncture on the immune function of sepsis patients.
METHODSNinety sepsis patients were assigned to the control group, the thymosin a1 group, and the acupuncture treatment group according to random digit table, 30 patients in each group. Patients in the control group were treated according to the guideline of Surviving Sepsis Campaign (SSC). Patients in the control group received routine treatment. Those in the thymosin alpha1 group additionally received subdermal injection of thymosin alpha1 (1.6 mg), once per day for 6 successive days. Needling at related points such as Zusanli (ST36), Yanglingquan (GB34), Neiguan (PC6), Guanyuan (RN4), and so on, was performed in patients of the acupuncture treatment group, once per day for 6 successive days. T cell subgroups (CD3+, CD4+, CD8+, CD4+ /CD8+) and immunoglobulin levels (IgG, IgA, IgM) were detected. The length of ICU hospital stay, hospital readmission rate, and 28-day mortality were compared among the three groups.
RESULTSAfter six days of treatment, CD3+, CD4+, CD8+, IgG, IgA, IgM, and CD4+ /CD8+ ratio of three groups were all significantly increased (P < 0.01). Of them, CD3+, CD4+, CD8+, IgG, IgA, and IgM increased more significantly in the thymosin alpha1 group and the acupuncture treatment group (P < 0.01). Compared with the control group, the ICU hospitalization length was significantly shortened, the hospital readmission rate and the 28-day mortality were lower in the thymosin alpha1 group and the acupuncture treatment group (P < 0.05, P < 0.01). There was no statistical difference in each index between the thymosin alpha1 group and the acupuncture treatment group (P > 0.05).
CONCLUSIONAcupuncture could adjust the immune function of sepsis patients, improve their immunological indicators and prognoses.
Acupuncture Therapy ; CD4-CD8 Ratio ; Humans ; Length of Stay ; Prognosis ; Sepsis ; diagnosis ; immunology ; therapy ; T-Lymphocyte Subsets ; Thymosin ; analogs & derivatives
4.The relationship between self-esteem and childhood abuse, life events among violent male adolescents
Zhili ZOU ; Huaqing MENG ; Hua HU ; Hui WANG ; Huaping LIANG ; Lian DU ; Yuan QU ; Na YONG
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(4):363-365
Objective To study the relationship between self-esteem and childhood abuse, life events among male violent adolescent. Methods According to the modified overt aggression scale, juvenile delinquents were divided into violent group (n = 128 )and nonviolent group (n = 118 ). All the participants were investigated by Self-Esteem Scale (SES), Childhood Trauma Questionnaire-28 Item Short Form (CTQ-SF) and Adolescent SelfRating Life Events (ASLEC) and conducted correlation and regression analysis. Results ①Violent group had lower self-esteem scores ( 22.73 ± 3.30 ) than the nonviolent group ( 23.81 ± 3.30, P < 0.05 ). Violent group had higher scores in physical abuse, sexual abuse, total life events, interpersonal relationship, punishment, and other (8.30 ±4.07, 7.23 ±2.26, 54.48 ±18.60, 10.09 ±3.84, 14.43 ±5.87, 4.93 ±3.15, 9.93 ±3.64), compared to the nonviolent group (7.27 ± 3.27, 6.60 ± 2.09, 45.40 ± 18.45, 8.42 ± 4.13, 11.07 ± 5.75, 3.66 ±2.81, 7.84 ±3.66, P<0. 05). ②The self-esteem was significantly negative correlated with the childhood abuse and life events( r= -0. 143 ~ -0. 358, P< 0.01 ) among violent male adolescents. ③The physical abuse and punishment had significant prediction function of 15.6% on self-esteem. Conclusions Violent adolescents have low self-esteem, which is closely related to childhood abuse and adolescent life events.
5.Sonographic assessment for breast augmentation by repeated injection of low volume of autologous fat
Hongyan WANG ; Yuxin JIANG ; Hua MENG ; Keming QI ; Zhifei LIU ; Yuan YU
Chinese Journal of Medical Aesthetics and Cosmetology 2010;16(2):90-93
Objective To assess the absorbance rate of the fat after the operation of breast augmentation of the repeated injection of low volume, using ultrasonic imaging method. Methods Thirty three patients were injected with low volume of autologous fat (50-60 ml per time) to bilateral breasts for 1-5 times and breast sonographic examination was performed to evaluate the grafted fat tissues. The thickness of the retromammary fat layer before and after each injection was measured to calculate the absorbance index. Results The 264 points of breast were measured in this study. The fat was distributed in the retro-mammary fat layers at 224 points of the breast and in the pectoralis major muscle layer at 32 points of the breast, and the others distributed in the mammary gland layer.The average thickness of the retromammary fat layer increased gradually from 0.2 cm before the first operation to 1. 0 cm after the fifth operation. The average absorbance index one month after each operation was 34 %-66 %. Conclusion The present study demonstrates that breast augmentation by repeated autologous fat graft with low volume injection at each time is applicable and satisfactory and that breast ultrasound is an accurate and simple method to e-valuate the absorbance index.
6.Association between Graves'disease and polymorphism of CTLA-4 gene in patients of the Han nationality in Tianjin area
Peng ZHANG ; Mei LI ; Yong ZHAO ; Meng-Hua YUAN ; Ming-Cai QIU ;
Chinese Journal of Endocrinology and Metabolism 1986;0(03):-
The polymorphism of (AT) repeat within the 3' untranslated region in exon 3 of CTLA-4 gene was evaluated by PCR-SSCP in 139 patients with Graves' disease (GD) and 110 normal subjects in Tianjin. The gene frequency of 106 bp in patients with GD was significantly increased than that in the control group (RR =1.992,P
7.Effects of left ventricular geometric patterns on cardiac function and carotid artery structure in elderly patients with essential hypertension
chao, MENG ; ya-ping, YI ; hui-hua, LU ; ning-yuan, FANG
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(05):-
Objective To observe the changes of cardiac function and carotid artery structure in elderly hypertensive patients with different left ventricular geometric patterns. Methods Seventy-eight elderly patients with essential hypertension were divided into 4 groups according to left ventricular geometric patterns by ultrasonography: normal ventricular geometry group(n=34),concentric remodeling group(n=18),concentric hypertrophy group(n=11)and eccentric hypertrophy group(n=15).The 24-h ambulatory blood pressure,left ventricular function,carotid artery intima-media thickness(IMT),hemodynamic parameters and incidence of plaque were measured and compared among groups.Results Patients in concentric hypertrophy group had higher 24-h average systolic blood pressure in comparison with those in normal ventricular geometry group and concentric remodeling group(P
8.Effect of acupuncture on acute left heart failure by PiCCO technique.
Qiu-Sheng XIAO ; Bin ZHANG ; Ming-Yuan MA ; Meng-Hua DENG ; Yan-Zhu YANG
Chinese Journal of Integrated Traditional and Western Medicine 2014;34(2):149-152
OBJECTIVETo observe the clinical effect of acupuncture on acute heart failure (AHF) patients.
METHODSTotally 60 patients who were diagnosed as AHF were assigned to the acupuncture group and the control group, 30 in each group. Those in the control group received inotropic agents, preload and afterload reducing therapy, anti-infection and so on. Besides, those in the acupuncture group received needling at relative points, once daily for 5 consecutive days. The mean arterial pressure (MAP), heart rate (HR), cardiac index (CI), stroke volume index (SI), left ventricle working index (LCWI) were monitored by thermodilution pulse-indicated continuous cardiac output (PiCCO) technique. Changes of the aforesaid data were compared between before and after treatment. The ICU length of stay, readmission rate,and the 28-day mortality were also compared between the two groups.
RESULTSAfter 5 days of the treatment, CI, SI, and LCWI increased more obviously (P < 0.01), HR and MAP decreased significantly (P < 0.05). Of them, CI, SI, and LCWI increased more obviously in the acupuncture group (P < 0.05).There was no obvious difference in HR or MAP between the two groups (P > 0.05). Compared with the first day of admission in the same group, CI, SI, and LCWI obviously increased in the acupuncture group from the second day (P < 0.05). HR started to decrease since the fourth day (P < 0.05), and MAP began to decrease until the fifth day (P < 0.05). CI, SI, and LCWI started to increase in the control group from the third day (P < 0.05); HR and MAP both began to decrease since the fifth day (P < 0.05). Compared with the control group, the ICU length of stay was obviously shortened in the acupuncture group (P < 0.05). The readmission rate and the 28-day mortality rate were lower than those of the control group (P < 0.05).
CONCLUSIONThe combination of acupuncture and Western medical therapy might strengthen acute heart failure patients' heart functions, elevate the therapeutic effect, and improve the prognosis.
Acupuncture Therapy ; Adult ; Aged ; Aged, 80 and over ; Female ; Heart Failure ; physiopathology ; therapy ; Heart Rate ; Humans ; Male ; Middle Aged ; Stroke Volume
9.Study on effects of different infusion sets on absorption of butylphthalide sodium chloride injection
Yuan-Yuan XIAO ; Chun-Hua ZHOU ; De-Qiang LI ; Meng XU
The Chinese Journal of Clinical Pharmacology 2017;33(7):634-637
Objective To investigate the absorbability of the packaged infusion sets of butylphthalide,polyvinyl chloride (PVC) or polyolefin thermoplastic elastomer (TPE) infusion sets on butylphthalide for providing clinical reference in the choice of infusion sets.Methods Solution of butylphthalide was prepared as peractual concentration needed by the clinic,and dripped through PVC,TPE and packaged infusion sets respectively.The dripped solutions at different time points were collected and determined by HPLC,the contents were compared with that at 0 min.Results In the end of infusion,the adsorption rate of PVC,TPE and packaged infusion sets on butylphthalide were 0.47%,32.48%,9.62%,respectively.In addition,the absorbability of the infusion sets frown different manfacturers on butylphthalide had no significant differece.Conclusion The infusion sets of PVC had a serious absorption on butylphthalide.
10.Experiment of Exploring Experiment Teaching in Microbiology
Gui-Hua JIN ; Hong-Hua LI ; Quan-Xin JIN ; Chang-Yuan SUN ; Ying-Xin LI ; Fan-Ping MENG ;
Chinese Journal of Medical Education Research 2006;0(10):-
Quality education and innovative ability cultivation of students are a new position in higher education.Exploring exper- iment was applied in teaching of microbiological experiment for enhancing integrative diathesis and cultivating innovative spirit and ability of students.The practice has been proved that learning fervor of students was increased adequately.Unaided operation abili- ty,integrative analysis ability and innovative idea were enhanced,too.Accordingly,teaching quality of microbiological experiment was improved.