ABSTRACT There is few drug made in China for curing Codyloma acuminata(CA.'). We manu factured a kind of gel for curing CA with a relatively new marine drug and a anti-cancer medicine i. e a derivative of cantharidin. The clinical observation on 58 patients with a total effective rate of 96. 5 per cent showed that the prescription is reasonably made up玹he new dosage form has a lasting curative effect in curing CA. It is used easily and has no toxicity,or allergic reaction.