1.Analysis on Present Situation and Countermeasures in Management of Medical Consumables
Chinese Medical Equipment Journal 2003;0(10):-
By analyzing the present defects in the management of medical consumables which include lagged management model,nonstandard storage names of medical consumables and bad traceability of the implanted medical products,this paper puts forward some corresponding improvement measures,such as changing the management model of medical consumables,standardizing the storage names of medical consumables and establishing information management system for tracing the implanted medical products,so as to realize scientific and appropriate management of medical consumables.
2.Direct antiglobulin test of bone marrow monouclear cells:Results of 270 cases with autoimmune hemocytopenia.
Juan SUN ; Zeng CAO ; Meifeng TU ; Al ET ;
Chinese Journal of Practical Internal Medicine 2006;0(S2):-
Objective To evaluate the specificity,sensitivity and clinical significances of direct antiglobulin test of bone marrow monouclear cells (BMMNC-Coombs test) and Flow Cytometry (FACS).Methods Autoantibodies on bone marrow mononuclear cells of 270 patients with immune and 471cases with primary or secondary anaemia and 19 normal controls were measured by BMMNC-Coombs test,and a part of IRP patients with negative BMMNC-Coombs test were retested by FACS.Results In 270 immune hemocytopenia patients,there were 163 (60.37%) with positive BMMNC -Coombs test.The positive rate of patients with immunorelated pancytopenia (IRP) was upmost and accounted for 67.2%.AIHA 63.6%,ITP 57.1%,Evans syndrome 43.2%.Both 471 patients with primary or secondary anaemia and 19 normal persons were all negative.In BMMNC-Coombs positive cases,there were mainly three types including IgG,IgG+C_3,IgG+IgM+IgA+C_3,they accounted for 30.4%,26.4%,20.8%.61 1RP with negative BMMNC-Coombs test were teased again for their BMMNC autoantibodies by FACS.83.6% of them were found to be positive with autoantibodies on BMMNC.The positive rate of autoantibodies on hematopoietic stem cells of IRP patients was 94.1%.it was higher than positive rate on any other types of bone marrow hematopoietic cells.Conclusion the sensitivity and specificity of BMMNC-Coombs test for diagnosis of autoimmune hemocytopenia was high,but the sensi- tivity of FACS assay was higher than that of BMMNC-Coombs test for detecting autoantibodies.Also had IRP,AIHA, ITP and Evans syndrome patients autoantibodies on bone marrow hematopoietic cells,The difference between IRP and other immune hemocytopenias was that IRP patients did have autoantibodies only on BMMNC.