1.Preparation & Stability of Chlorhexidine-iodine Complex Salt Solution
Journal of Third Military Medical University 1984;0(01):-
Chlorhexidine-iodine complex salt solution was prepared with polyethylene glycol 400 as the solvent and ethanol as the disperser. Polyethylene glycol 400 is thermoresistant, stable, odorless and not irritative, and it can promote the solubility of the complex salt. Ethanol can accelerate the dissolution speed of the complex salt in polyethelene glycol and make the solution more translucent.The solution so prepared is relatively stable.
2.Associations between the behavioral psychological symptoms in Alzheimer's disease and cerebral blood flow in cerebral heteroplasia cortex
Hongmei FU ; Zhengwan QU ; Zhen TANG ; Meidi CHEN ; Linghua SHI ; Feng CHEN ; Qi JIANG ; Lina ZHU ; Zhengyi CAI
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(3):244-246
Objective To explore the relationship between behavioral psychological symptoms in Alzheimer' s dementia(AD) patients and region-specific alterations in cerebral blood flow. Methods 60 patients with AD randomly selected from a psychiatric outpatient department and 30 randomly selected healthy elderly community controls were administered the Mini-Mental State Exam (MMSE). All subjects underwent a perfusion CT scan to assess blood perfusion in brain regions of interest. The AD subjects were administered the behavioral patholigy in alzheimer' s disease(BEHAVE-AD) Rating Scale classified as mild, moderate or severe based on the results of the Clinical Dementia Rating scale. Results The most incidence was conduct disorder and the next was delusion.The score was 81.7% and 58.3% in turn. The conduct disorder score was higher in the severe demented group than in the mildly and moderate demented group(P<0. 05). The delusion score was higher in the moderate demented group than that in the mildly demented group(P<0.05). The time to peak(TTP)scores in the four groups of subjects were significantly different in the bilateral hippocampal formation, anteroinferior subiculum and entorhinal area. The TTP score was significantly higher in the moderately demented group than that in the mildly demented group and the control group(P<0. 05 ). Correlation analysis identified a positive correlation between conduct disorder, delusions and TTP in cerebral heteroplasia cortex (P < 0. 05 ), also identified a negative correlation between mood disorder and TTP(P<0. 05 ). Conclusion The conduct disorder,delusions and mood disorder in AD are associated with the chronicity ischemia of cerebral heteroplasia cortex leading to neural conduction disorders.