1.Research on ereythropoietin and its receptor in anemia of neoplasm
Journal of Leukemia & Lymphoma 2008;17(3):231-233
The anemia of chronic disease is chronic infection, inflammation, a class of cancer-related anemia syndrome, anemia in patients with malignant tumors often. In recent years recombinant human erythropoietin, widely used in clinical treatment of anemia, Especially in cancer-related anemia treatment achieved remarkable results, a blood transfusion to avoid the many adverse effects and improve the patient' s quality of life. A control chemotherapy-induced anemia is an important choice. Therefore, rhEPO on cancer-related anemia treatment mechanism has also become a research hotspot.
2. Hippocampus glioma with temporal lobe epilepsy as the main manifestation: The clinicopathologic properties
Academic Journal of Second Military Medical University 2010;31(1):60-62
Objective: To study the clinicopathologic properties of hippocampus glioma with temporal lobe epilepsy(TLE) as the main manifestation. Methods: The clinical data of 6 patients with TLE and hippocampus masses were retrospectively analyzed. The 6 patients included 2 males and 4 females, with the longest history of epilepsy being 4 years. Results: All the 6 patients were surgically treated and were pathologically confirmed to have gliomas, including one angiocentric glioma( AG), one pilocytic astrocytoma (PA) with mucous degeneration, one astrocytoma, one oligoastrocytomao, one oligodendroglioma and one glioblastoma. Glial fibrillary acidic protein(GFAP) was strongly positive in all cases. Epilepsy disappeared after surgery in 5 cases; one patient had recurrence and received a second operation. Conclusion: Hippocampus gliomas with TLE as the main manifestation are usually low-grade gliomas of various types, and operation can obtain satisfactory prognosis.
3.The 6th National Conference on Hematology of Ingrative Traditional Chinese and Western Medicine.
Feng LIU ; Xiao-mei HU ; Rou MA
Chinese Journal of Integrated Traditional and Western Medicine 2003;23(4):319-320
Anemia, Aplastic
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drug therapy
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Animals
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Drugs, Chinese Herbal
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therapeutic use
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Humans
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Leukemia, Myeloid, Acute
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drug therapy
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Medicine, Chinese Traditional
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Phytotherapy
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Precursor Cell Lymphoblastic Leukemia-Lymphoma
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drug therapy
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Purpura, Thrombocytopenic, Idiopathic
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drug therapy
4.A preliminary study of the relationship between Sema4A gene expression and Th cytokines in immune thrombocytopenia.
Hu ZHOU ; Hong-mei WANG ; Li MA
Chinese Journal of Hematology 2011;32(9):622-623
Adult
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Cytokines
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metabolism
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Female
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Gene Expression
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Humans
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Interleukin-2
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blood
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Interleukin-4
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blood
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Male
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Semaphorins
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genetics
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metabolism
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T-Lymphocytes, Helper-Inducer
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metabolism
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Thrombocytopenia
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genetics
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metabolism
7.Research on practice rights of medical colleges and analysis on the countermeasures
Lingna MA ; Mei YIN ; Dexin MENG
Chinese Journal of Medical Education Research 2012;11(6):569-571
Analysis was conducted and rights concerning teachers,students and patients in practice teaching was defined from the perspectives of medicine,pedagogy,ethnics and law through investigating on reasons leading to problems and conflicts in medical universities' practice right.Effective solutions were proposed from the examination of doctor' s qualification,law and pedagogy.Standardization and legalization of clinical teaching was promoted from the perspective of ethnics.
8.Clinical pathological analysis in 14 cases of pancreatic solid-pseudopapillary tumors
Fang MEI ; Juan DU ; Xiaolong MA
Journal of Peking University(Health Sciences) 2009;41(6):652-656
Objective:To observe clinical and pathological features of pancreatic solid-pseudopapillary tumor ( SPPT) , and to find some useful immunohistochemical methods for its differential diagnosis.Methods: The clinical features of 14 SPPT patients were obtained. Each case underwent microscopic observation and immunohistochemical staining. The primary antibodies were CgA, Syn, E-cadherin, β-catenin and Cyclin Dl. These results were compared with 5 pancreatic well-differentiated tumors and well-differentiated carcinomas ( WET/WEC). Results: SPPT mainly involved young women, and the head of pancreas was the commonest location. Tumors were always in solid and cystic gross appearance.Although the tumor' s borderlines seemed clear, focal infiltrations could often be identified. The histological features of SPPT were similar in some aspects to those of WET/WEC, especially the solid pattern of WET/WEC. Both of them could express CgA and Syn. But all SPPTs lost E-cadherin membranous signals, and even had some nuclear signals (5/14) , while all WET/WECs remained the same staining pattern with normal pancreas cells, β-catenin positive signals in SPPTs were located both in nuclei and plas mas. WET/WECs' positive signals were all in membranes and plasmas, but negative ones in nuclei. Perinuclear dot-like signals could also be seen in the majority cells, which were similar to normal islet cells' staining pattern. SPPTs' nuclear positive rates of Cyclin Dl were usually more than 70% (12/14). WET/WECs' rates were all lower than 30%. Conclusion: Comprehensive analysis of patients'clinical, pathological features and immunohistoehemistry results, including E-cadherin, β-catenin and Cyclin Dl, was helpful to the diagnosis of SPPT and its differential diagnosis of WET/WEC.
9.Building the Curriculum and Content of Special Physical Education Based on the ICF
Chinese Journal of Rehabilitation Theory and Practice 2014;(6):513-516
This research was based on the theory and method of International Classification of Function, Disability and Health (ICF) and looked into the issues of physical function and disability. It tried to explore the purpose, knowledge structure and curriculum of special physical education that met the needs of social development and to restructure the curriculum and content of special physical education. Stu-dents of special physical education should not only master basic specialized knowledge, but also be able to practice theories, so as to better serve all kinds of children with special needs in training, assessment and intervention.
10.The Relationship between Serum Fibrinogen,Uric Acid and the Severity of Coronary Artery Diseases
Mei MA ; Xuemei GAO ; Lihua HE
Chinese Journal of Prevention and Control of Chronic Diseases 2006;0(02):-
Objective To study the relationship between serum fibrinogen,uric acid and the severity of coronary heart disease(CHD).Methods 156 patients with or without coronary heart disease were divided into CHD group and control group.All subjects were examined by cronary artery angiography.The severity of coronary artery stenosis was evaluated and graded with Leaman coronary scoring system.With the multiple analysis method,the relationships were studied between serum fibrinogen,uric acid and the severity of coronary heart disease.Results With multiple logistic regression,smoking,age,fibrinogen,triglyceride and low-density lipoprotein were independently associated with the severity of coronary heart disease.Gender,uric acid and other variables did not have significant independently association with the severity of coronary heart disease.With stepwise multiple regression analysis,age,fibrinogen,total cholesterol,lipoprotein(a)and low density cholesterol showed significant independent association with the severity of coronary heart disease,but uric acid and other variables did not.Conclusion Fibrinogen was related to the severity of coronary heart disease independently,but uric acid was not independently associated with the severity of coronary heart disease.