1.All-arthroscopic, Guideless Single Suture-button Fixation of Acute Acromioclavicular Joint Dislocation: A Description of the Technique and Early Treatment Results.
Burak ALTINTAS ; Fatih YILDIZ ; Gokcer UZER ; Mehmet KAPICIOGLU ; Kerem BILSEL
Clinics in Shoulder and Elbow 2017;20(2):59-67
BACKGROUND: The purpose of this study was to examine the clinical and radiological results of the all-arthroscopic, suture-button fixation technique to treat acute acromioclavicular (AC) joint separations. METHODS: All patients with acute AC joint separations received all-arthroscopic, single suture-button (TightRope) procedure without a special guide. Postoperative Constant score (CS), pain level according to visual analogue scale, and range of motion (ROM) were evaluated. For radiological evaluation, coracoclavicular distances were measured bilaterally. RESULTS: Between December 2010 and June 2012, 18 consecutive patients (4 women and 14 men; mean age, 29.3 years) with acute AC joint separations underwent surgical treatment after 6.4 days (range, 2–20 days) following the initial trauma. The average postoperative follow-up was 16.9 months. The mean CS was 92.4 (range, 84–96). The mean external rotation, forward flexion, and abduction were 75.8° (range, 50°–90°), 170° (range, 150°–180°), and 163.8° (range, 140°–180°), respectively. Five patients exhibited coracoclavicular ossifications. In two patients, superficial wound infections were successfully treated with antibiotic therapy. In one patient, a coracoid fracture was observed. No significant differences were found regarding pain, ROM, or strength parameters between both sides. The coracoclavicular distance was discovered to be approximately 2.8 mm greater on the affected side; however, this minimal reduction loss did not affect the functional results. CONCLUSIONS: The findings of this study suggests that all-arthroscopic treatment of AC joint separations using the single suture-button technique without a drill guide is safe, yielding good to excellent clinical results.
2.Acute Pancreatitis and Gastroduodenal Intussusception Induced by an Underlying Gastric Gastrointestinal Stromal Tumor: A Case Report.
Mehmet Siddik YILDIZ ; Ahmet DOĞAN ; Ibrahim Halil KOPARAN ; Mehmet Emin ADIN
Journal of Gastric Cancer 2016;16(1):54-57
Gastrointestinal stromal tumors (GISTs) are rare tumors of the gastrointestinal system and comprise only 1% to 3% of all gastrointestinal tract tumors, with the majority of them arising in the stomach. In this report, we present the unique findings of a case of gastroduodenal intussusception caused by an underlying gastric GIST and complicated with severe acute pancreatitis.
Gastrointestinal Stromal Tumors*
;
Gastrointestinal Tract
;
Intussusception*
;
Pancreatitis*
;
Pancreatitis, Acute Necrotizing
;
Stomach
3.All-arthroscopic, Guideless Single Suture-button Fixation of Acute Acromioclavicular Joint Dislocation: A Description of the Technique and Early Treatment Results
Burak ALTINTAS ; Fatih YILDIZ ; Gokcer UZER ; Mehmet KAPICIOGLU ; Kerem BILSEL
Journal of the Korean Shoulder and Elbow Society 2017;20(2):59-67
BACKGROUND: The purpose of this study was to examine the clinical and radiological results of the all-arthroscopic, suture-button fixation technique to treat acute acromioclavicular (AC) joint separations. METHODS: All patients with acute AC joint separations received all-arthroscopic, single suture-button (TightRope) procedure without a special guide. Postoperative Constant score (CS), pain level according to visual analogue scale, and range of motion (ROM) were evaluated. For radiological evaluation, coracoclavicular distances were measured bilaterally. RESULTS: Between December 2010 and June 2012, 18 consecutive patients (4 women and 14 men; mean age, 29.3 years) with acute AC joint separations underwent surgical treatment after 6.4 days (range, 2–20 days) following the initial trauma. The average postoperative follow-up was 16.9 months. The mean CS was 92.4 (range, 84–96). The mean external rotation, forward flexion, and abduction were 75.8° (range, 50°–90°), 170° (range, 150°–180°), and 163.8° (range, 140°–180°), respectively. Five patients exhibited coracoclavicular ossifications. In two patients, superficial wound infections were successfully treated with antibiotic therapy. In one patient, a coracoid fracture was observed. No significant differences were found regarding pain, ROM, or strength parameters between both sides. The coracoclavicular distance was discovered to be approximately 2.8 mm greater on the affected side; however, this minimal reduction loss did not affect the functional results. CONCLUSIONS: The findings of this study suggests that all-arthroscopic treatment of AC joint separations using the single suture-button technique without a drill guide is safe, yielding good to excellent clinical results.
Acromioclavicular Joint
;
Dislocations
;
Female
;
Follow-Up Studies
;
Humans
;
Joints
;
Male
;
Range of Motion, Articular
;
Wound Infection
4.NT-proBNP levels and QT changes in acute ischemic stroke
Ayca Acikalin ; Salim Satar ; Onur Akpinar ; Caglar Emre Cagliyan ; Mustafa Sahan ; Ferhat Icme ; Muge Gulen ; Mehmet Yildiz
Neurology Asia 2013;18(1):1-8
Background: In literature, electrocardiographic (ECG) changes and the increase in the levels of the
natriuretic peptide are shown to occur in patients having acute ischemic stroke. We aimed to investigate
the association between ECG alterations and NT pro B-type natriuretic peptide (NT-proBNP) values
in patients having acute ischemic stroke with no known cardiac pathology. Methods: The patients who
admitted to the emergency service with acute ischemic stroke were enrolled in the study. Their ECGs
were recorded and serum samples were obtained as soon as they arrived into the emergency service.
The plasma NT-proBNP levels were measured by electrochemiluminescence method. Maximum QT
interval, QT dispersion (QTd), corrected QT and corrected QTd (cQT and cQTd) was calculated, for
each ECG. The patients were evaluated according to the Glasgow Coma Scale (GCS) and National
Institutes of Health Stroke Scale (NIHSS). Results: A total of 50 consecutive patients were evaluated.
QT intervals for 4 patients (8%) and cQT intervals for 29 patients (58%) were above 440 ms and 11
patients (22%) had QTd values above 50ms and 17 (34%) had cQTd values above 50 ms. The NTproBNP
levels had a negative correlation with the GCS (p=0.001, r= -0.461) and a positive correlation
with the NIHSS, cQT, QTd and cQTd (p=0.001, r=0.444, p=0.000, r=0.494, p=0.016, r=0.338 p=0.011,
r=0.355, respectively).
Conclusions: The NT-proBNP levels in the ischemic stroke patients with no known cardiac pathology
were markedly increased, and this increase was found to be associated with the GCS, NIHSS, cQT,
QTd and the cQTd interval.
5.Sepsis and Meningitis due to Listeria Monocytogenes.
Orhan YILDIZ ; Bilgehan AYGEN ; Duygu ESEL ; Uner KAYABAS ; Emine ALP ; Bulent SUMERKAN ; Mehmet DOGANAY
Yonsei Medical Journal 2007;48(3):433-439
PURPOSE: This study focused on the effect of immuno-compromising conditions on the clinical presentation of severe listerial infection. PATIENTS AND METHODS: Nine human listeriosis cases seen from 1991-2002 were reviewed. All adult patients, from whose blood, peritoneal fluid or cerebrospinal fluid (CSF) the L. monocytogenes was isolated, were included in this retrospective study. RESULTS: Listeriosis presented as primary sepsis with positive blood cultures in 5 cases and meningitis with positive CSF cultures in 4 cases. All of these patients had at least one underlying disease, most commonly, hematologic malignancy, diabetes mellitus, amyloidosis and hepatic cirrhosis; 55.6% had received immunosuppressive or corticosteroid therapy within a week before the onset of listeriosis. The patients were adults with a mean age of 60 years. Fever, night sweats, chills and lethargy were the most common symptoms; high temperature (> 38 degrees C), tachycardia, meningeal signs and poor conditions in general were the most common findings on admission. The mortality rate was 33.3% and was strictly associated with the severity of the underlying disease. Mortality differences were significant between sepsis (20%) and meningitis (50%) patients. CONCLUSION: Listeriosis as an uncommon infection in our region and that immuno- suppressive therapy is an important pre-disposing factor of listeriosis. Sepsis and meningitis were more common in this group of patients and had the highest case-fatality rate for food-borne illnesses.
Adrenal Cortex Hormones/therapeutic use
;
Adult
;
Aged
;
Ascitic Fluid/microbiology
;
Female
;
Humans
;
Immunosuppressive Agents/*therapeutic use
;
Listeria Infections/blood/cerebrospinal fluid/*drug therapy
;
Listeria monocytogenes/*drug effects/growth & development/isolation & purification
;
Male
;
Meningitis, Bacterial/blood/cerebrospinal fluid/*drug therapy
;
Middle Aged
;
Retrospective Studies
;
Sepsis/blood/cerebrospinal fluid/*drug therapy
;
Treatment Outcome
6.The effects of different polishing techniques on the staining resistance of CAD/CAM resin-ceramics.
Omer SAGSOZ ; Tevfik DEMIRCI ; Gamze DEMIRCI ; Nurdan Polat SAGSOZ ; Mehmet YILDIZ
The Journal of Advanced Prosthodontics 2016;8(6):417-422
PURPOSE: The purposes of this study were to evaluate the staining resistance of CAD/CAM resin-ceramics polished with different techniques and to determine the effectiveness of the polishing techniques on resin-ceramics, comparing it with that of a glazed glass-ceramic. MATERIALS AND METHODS: Four different CAD/CAM ceramics (feldspathic ceramic: C-CEREC Blocs, (SIRONA) and three resin-ceramics: L-Lava Ultimate, (3M ESPE), E-Enamic, (VITA) and CS-CeraSmart, (GC)) and one light cure composite resin: ME-Clearfil Majesty Esthetic (Kuraray) were used. Only C samples were glazed (gl). Other restorations were divided into four groups according to the polishing technique: nonpolished control group (c), a group polished with light cure liquid polish (Biscover LV BISCO) (bb), a group polished with ceramic polishing kit (Diapol, EVE) (cd), and a group polished with composite polishing kit (Clearfil Twist Dia, Kuraray) (kc). Glazed C samples and the polished samples were further divided into four subgroups and immersed into different solutions: distilled water, tea, coffee, and fermented black carrot juice. Eight samples (8 × 8 × 1 mm) were prepared for each subgroup. According to CIELab system, four color measurements were made: before immersion, immersion after 1 day, after 1 week, and after 1 month. Data were analyzed with repeated measures of ANOVA (α=.05). RESULTS: The highest staining resistance was found in gl samples. There was no difference among gl, kc and cd (P>.05). Staining resistance of gl was significantly higher than that of bb (P<.05). Staining resistances of E and CS were significantly higher than those of L and ME (P<.05). CONCLUSION: Ceramic and composite polishing kits can be used for resin ceramics as a counterpart of glazing procedure used for full ceramic materials. Liquid polish has limited indications for resin ceramics.
Ceramics
;
Coffee
;
Daucus carota
;
Immersion
;
Tea
;
Water
7.Open healing of contained and noncontained extraction sockets covered with a ribose cross-linked collagen membrane: a pilot study
Anton FRIEDMANN ; Viktorija MESKELEVICIENE ; Mehmet Selim YILDIZ ; Werner GÖTZ ; Jung-Chul PARK ; Kai R. FISCHER
Journal of Periodontal & Implant Science 2020;50(6):406-417
Purpose:
This study investigated whether the placement of ribose cross-linked collagen (RCLC) membranes without primary soft tissue closure predictably resulted in sufficient alveolar ridge preservation in contained and non-contained extraction sockets.
Methods:
Membranes were positioned across extraction sockets, undermining full-thickness flaps, and the gingival margins were fixed by double-interrupted sutures without crossed horizontal mattress sutures for 1 week. In non-contained sockets, a bone substitute was used to support the membrane within the bony envelope. Radiographs and clinical images obtained 4 months later were analyzed by ImageJ software using non-parametric tests.
Results:
In 18 patients, 20 extraction sockets healed uneventfully and all sites received standard-diameter implants (4.1, 4.8, or 5.0 mm) without additional bone augmentation.Soft tissues and the muco-gingival border were well maintained. A retrospective analysis of X-rays and clinical photographs showed non-significant shrinkage in the vertical and horizontal dimensions (P=0.575 and P=0.444, respectively). The new bone contained vital bone cells embedded in mineralized tissues.
Conclusions
Within the limitations of this pilot study, open healing of RCLC membranes may result in sufficient bone volume for implant placement without additional bone augmentation in contained and non-contained extraction sockets.
8.Apelin Levels In Isolated Coronary Artery Ectasia.
Mehmet Zihni BILIK ; Ibrahim KAPLAN ; Abdulkadir YILDIZ ; Mehmet Ata AKIL ; Halit ACET ; Murat YUKSEL ; Nihat POLAT ; Mesut AYDIN ; Mustafa OYLUMLU ; Faruk ERTAS ; Hasan KAYA ; Sait ALAN
Korean Circulation Journal 2015;45(5):386-390
BACKGROUND AND OBJECTIVES: The etiopathogenesis of coronary artery ectasia (CAE) is not known completely. In most of the cases, CAE is associated with atherosclerosis; however, isolated CAE has a nonatherosclerotic mechanism. The association between atherosclerotic coronary artery disease and apelin has been examined in previous studies. However, the role of plasma apelin in isolated coronary artery ectasia has not been studied. In this study, we investigated the relationship between plasma apelin levels and isolated coronary artery ectasia. SUBJECTS AND METHODS: The study population included a total of 54 patients. Twenty-six patients had isolated CAE (53.6+/-8.1 years); 28 patients with normal coronary arteries (51.6+/-8.8 years) and with similar risk factors and demographic characteristics served as the control group. Apelin levels were measured using an enzyme-linked immunoassay kit. RESULTS: Apelin level in the CAE group was significantly lower (apelin=0.181+/-0.159 ng/mL) than that in the control group (apelin=0.646+/-0.578 ng/mL) (p=0.033). Glucose, creatinine, total cholesterol, triglyceride, low density lipoprotein cholesterol, and high density lipoprotein cholesterol levels were not significantly different between the two groups. CONCLUSION: In this study, we showed that patients with isolated CAE have decreased plasma apelin levels compared with the control group. Based on the data, a relationship between plasma apelin and isolated CAE was determined.
Atherosclerosis
;
Cholesterol
;
Cholesterol, HDL
;
Cholesterol, LDL
;
Coronary Artery Disease
;
Coronary Vessels*
;
Creatinine
;
Dilatation, Pathologic*
;
Glucose
;
Humans
;
Immunoassay
;
Inflammation
;
Plasma
;
Risk Factors
;
Triglycerides
9.Glial Cell Line-Derived Neurotrophic Factor, S-100 Protein and Synaptophysin Expression in Biliary Atresia Gallbladder Tissue
Semra GÜRÜNLÜOĞLU ; Canan CERAN ; Kubilay GÜRÜNLÜOĞLU ; Alper KOÇBIYIK ; Mehmet GÜL ; Turan YILDIZ ; Harika Gözükara BAĞ ; Semir GÜL ; Aytaç TAŞÇI ; Ercan BAYRAKÇI ; Necmettin AKPINAR ; Ecem Serbest ÇIN ; Hasan ATEŞ ; Mehmet DEMIRCAN
Pediatric Gastroenterology, Hepatology & Nutrition 2021;24(2):173-186
Purpose:
Biliary atresia (BA) is a disease that manifests as jaundice after birth and leads to progressive destruction of the ductal system in the liver. The aim of this study was to investigate histopathological changes and immunohistochemically examine the expression of glial cell line-derived neurotrophic factor (GDNF), synaptophysin, and S-100 protein in the gallbladder of BA patients.
Methods:
The study included a BA group of 29 patients and a control group of 41 children with cholecystectomy. Gallbladder tissue removed during surgery was obtained and examined immunohistochemically and histopathologically. Tissue samples of both groups were immunohistochemically assessed in terms of GDNF, S-100 protein, and synaptophysin expression. Expression was classified as present or absent. Inflammatory activity assessment with hematoxylin and eosin staining and fibrosis assessment with Masson's trichrome staining were performed for tissue sample sections of both groups.
Results:
Ganglion cells were not present in gallbladder tissue samples of the BA group.Immunohistochemically, GDNF, synaptophysin, and S-100 expression was not detected in the BA group. Histopathological examination revealed more frequent fibrosis and slightly higher inflammatory activity in the BA than in the control group.
Conclusion
We speculate that GDNF expression will no longer continue in this region, when the damage caused by inflammation of the extrahepatic bile ducts reaches a critical threshold. The study's findings may represent a missing link in the chain of events forming the etiology of BA and may be helpful in its diagnosis.
10.Glial Cell Line-Derived Neurotrophic Factor, S-100 Protein and Synaptophysin Expression in Biliary Atresia Gallbladder Tissue
Semra GÜRÜNLÜOĞLU ; Canan CERAN ; Kubilay GÜRÜNLÜOĞLU ; Alper KOÇBIYIK ; Mehmet GÜL ; Turan YILDIZ ; Harika Gözükara BAĞ ; Semir GÜL ; Aytaç TAŞÇI ; Ercan BAYRAKÇI ; Necmettin AKPINAR ; Ecem Serbest ÇIN ; Hasan ATEŞ ; Mehmet DEMIRCAN
Pediatric Gastroenterology, Hepatology & Nutrition 2021;24(2):173-186
Purpose:
Biliary atresia (BA) is a disease that manifests as jaundice after birth and leads to progressive destruction of the ductal system in the liver. The aim of this study was to investigate histopathological changes and immunohistochemically examine the expression of glial cell line-derived neurotrophic factor (GDNF), synaptophysin, and S-100 protein in the gallbladder of BA patients.
Methods:
The study included a BA group of 29 patients and a control group of 41 children with cholecystectomy. Gallbladder tissue removed during surgery was obtained and examined immunohistochemically and histopathologically. Tissue samples of both groups were immunohistochemically assessed in terms of GDNF, S-100 protein, and synaptophysin expression. Expression was classified as present or absent. Inflammatory activity assessment with hematoxylin and eosin staining and fibrosis assessment with Masson's trichrome staining were performed for tissue sample sections of both groups.
Results:
Ganglion cells were not present in gallbladder tissue samples of the BA group.Immunohistochemically, GDNF, synaptophysin, and S-100 expression was not detected in the BA group. Histopathological examination revealed more frequent fibrosis and slightly higher inflammatory activity in the BA than in the control group.
Conclusion
We speculate that GDNF expression will no longer continue in this region, when the damage caused by inflammation of the extrahepatic bile ducts reaches a critical threshold. The study's findings may represent a missing link in the chain of events forming the etiology of BA and may be helpful in its diagnosis.