1.Isolation of Neissseria meningitidis from an unusual site.
Rina Karunakaran ; Yun Fong Ngeow ; Mazita Mashor
The Malaysian journal of pathology 2002;24(2):103-5
A 59-year-old post-menopausal lady who had returned from a pilgrimage to Mecca about a month earlier presented with a three days' history of profuse vaginal discharge. Neissseria meningitidis was isolated from high vaginal swab specimens taken from her on 2 occasions, five days apart. Her symptoms disappeared without treatment after two weeks. We conclude that although the organism may have been a colonizer, it is possible that it was responsible for the self-limiting genital infection in this patient.
Need for isolation
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g <3>
;
limitin
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symptoms <1>
;
pilgrimage
2.Larygospasm secondary to a multinodular goitre
Mohd Sazafi MOHD SAAD ; Esa KAMARUZAMAN ; Mazita AMI
Brunei International Medical Journal 2012;8(2):90-93
Laryngospasm is a serious event that can result in partial or complete upper airway obstruction. It is a common complication during recovery phase of anaesthesia, resulting from acute irritation of the vocal folds. We report a rare case of laryngospasm secondary to a multinodular goitre that settled after treatment. We postulate that the enlarged thyroid gland can lead to direct irritation of the laryngeal nerve as possible cause of repeated episodes of laryngospasm in this patient. To our knowledge, this is the first reported case of a multinodular goitre as the underlying cause of laryngospasm.
Airway Obstruction
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Laryngismus
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Goitre, Nodular
3.Oncocytic Schneiderian Papilloma: A Rare Sinonasal Papilloma Removed via Endoscopic Medial Maxillectomy
Faizah AR ; Mazita A ; Marina MB ; Jeevanan J ; Isa MR
Medicine and Health 2010;5(1):55-59
There are three types of papilloma which arises from the Schneiderian membrane namely inverted, fungiform and oncocytic. Oncocytic papilloma is the rarest type and
occurs predominantly in the older age group. Clinically, its behaviour is similar to inverted papilloma in having both local recurrence and associated malignancy. We
report a rare case of oncocytic papilloma arising from the maxillary sinus, extending into the nasal cavity and nasopharynx, in a 78-year-old lady. Despite the longstanding history there was no evidence of associated malignancy in this lesion. An endoscopic medial maxillectomy was successfully utilized for approach and complete tumour excision. In conclusion, oncocytic papilloma should be considered as a differential
diagnosis in patients presenting with unilateral polypoid nasal lesions especially in the elderly. In addition, endoscopic medial maxillectomy can provide an adequate
approach for complete tumour removal.
4.The lower cheek flap combined with neurosurgical approach for infratemporal fossa tumour.
Hamizan Aneeza Khairiyah W ; Ami Mazita ; Abu Bakar Azizi ; Yunus Mohd Razif Mohamad
Philippine Journal of Otolaryngology Head and Neck Surgery 2010;25(1):17-19
p style=text-align: justify;strongOBJECTIVE:/strong To describe our experience in performing the lower cheek flap for access to the infratemporal fossa combined with the neurosurgical approach. br /br /strongMETHODS:/strongbr /strongDesign:/strong Case report br /strongSetting:/strong Tertiary Referral Center br /strongPatients:/strong Two br /br /strongRESULTS:/strong Two unusual tumours involving the infratemporal and middle cranial fossa were excised using this combined appoach. The infratemporal fossa tumour was accessed via the lower cheek flap while the intracranial portion was resected from above via craniotomy.br /br /strongCONCLUSION:/strong The lower cheek flap in combination with the neurosurgical approach allows optimal exposure to tumours involving the infratemporal and middle cranial fossae. It has less complications and better aesthetic outcome compared to other approaches./p
Human
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Male
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Female
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Surgical Flaps
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Surgically-Created Structures
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Cheek
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Neoplasms
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Neurosurgical Procedures
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Cranial Fossa, Middle
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Infratentorial Neoplasms
5.Derivation of cochlea hair cell for in vitro expansion and characterization.
Ibnubaidah MA ; Chua KH ; Mazita A ; Azida ZN ; Aminuddin BS ; Ruszymah BH ; Lokman BS
The Medical Journal of Malaysia 2008;63 Suppl A():115-116
A potential cure for hearing loss would be to regenerate hair cells by stimulating cells of the damaged inner ear sensory epithelia to proliferate and differentiate into hair cells. Here, we investigated the possibility to isolate, culture-expand and characterize the cells from the cochlea membrane of adult mice. Our results showed that the cultured cells isolated from mouse cochlea membrane were heterogenous in nature. Morphologically there were epithelial like cells, hair cell like, nerve cell like and fibroblastic cells observed in the culture. The cultured cells were immunopositive for specific hair cell markers including Myosin 7a, Calretinin and Espin.
6.Bilateral microtia, canal atresia and aplasia of cochleovestibular nerve
Asma binti Abdullah ; Roslenda Abdul Rahman ; Fadzilah Ismail ; Mazita Ami ; Marina Mat Baki ; Aini Ab Aziz
The Medical Journal of Malaysia 2017;72(2):135-137
A six-month-old baby with congenital patent ductus
arteriosus (PDA), bilateral microtia and canal atresia was
referred for hearing assessment. The audiology assessment
revealed bilateral profound hearing loss, which is atypical
for a case of pure canal atresia. Imaging was performed
much earlier than usual and, as suspected, the patient also
had bilateral severe inner ear anomaly. It is extremely rare
for a person to have both external and inner ear anomaly
because of the different embryological origin. The only
suitable hearing rehabilitation option for this kind of patients
is brainstem implant. However, the parents had opted for
sign language as a form of communication.
KEY WORDS:
Microtia; canal atresia; cochleovestibular nerve aplasia; inner ear anomaly
Congenital Microtia
7.Retropharyngeal Abscess: A Seven-Year Review - Clinical Presentation, Diagnosis and Management
Abdul Fattah AW ; Marina MB ; Mazita A ; Mohd Razif MY ; Primuharsa Putra SHA
Medicine and Health 2009;4(2):84-90
This was a retrospective study of operative records between 2000 – 2007 from two ear, nose and throat (ENT) referral centers in Malaysia to review demographic patterns, clinical presentations and management of retropharyngeal abscess (RPA). Our case series comprised of eight patients with five females and three males with a median age at presentation of 47 years. Comorbid factor in this series was diabetes mellitus, with four patients having diabetes. There were three cases of fish bone ingestion. The commonest presentation was dysphagia or odynophagia. None of them had fever. All patients were treated with broad spectrum intravenous antibiotics (IV) and drainage was performed for the abscess. Four patients underwent transoral drainage with three having the cervical approach and one having spontaneous rupture. All patients recovered well from the infection and only one patient passed away due to septicaemia. In conclusion, patients with retropharyngeal abscess may present with vague symptoms of sore throat, odynophagia without fever due to partial antibiotics treatment. A correct diagnosis should be made so that adequate treatment can be given to prevent mortality.
8.Pleomorphic Adenoma Originating from Submandibular Salivary Gland in an 8-year-old Girl: A Case Report
Gani AN ; Megat Shiraz MAR ; Siti Aishah MA ; Norazizah M ; Mazita A ; Sharifah NA
Medicine and Health 2007;2(2):164-168
Pleomorphic adenoma (PA) typically presents as a benign slow growing, painless
neoplasm of the parotid gland. PA arising from the submandibular gland in the paediatric
age group is rare. Surgical excision is the treatment of choice. A case of PA in an 8-yearold
Malay girl is presented. Clinically she presented with a painless right submandibular
mass measuring 2x2cm. A diagnosis of Pleomorphic adenoma was made on Fine Needle
Aspiration Cytology (FNAC). She underwent submandibulectomy uneventfully.
Postoperatively after two years follow up, she is asymptomatic.
9.Acute Tonsillitis With Concurrent Kikuchi’s Disease as a Cause of Persistent Lymphadenopathy
Halimuddin Sawali ; Primuharsa Putra Sabir Husin Athar ; Mazita Ami ; Nor Hasni Shamsudin ; Gopalan Nair
Malaysian Journal of Medical Sciences 2009;16(4):73-76
We present a young adult female with symptoms of acute tonsillitis and tender cervical
lymphadenopathy. Despite a full course of oral antibiotics, she had persistent left lower cervical
lymphadenopathy measuring 2.0 x 1.5 cm at 2 weeks post-treatment. Rigid and flexible scope
examinations did not reveal any abnormalities in the nasopharynx, oropharynx or hypopharynx.
Tuberculosis tests were negative and blood index results were normal. Fine needle aspiration cytology
revealed a non-specific granulomatous inflammatory process. Excisional lymph node biopsy was
performed, and the patient was diagnosed as having Kikuchi’s Disease (KD). We would like to highlight
the diagnostic challenges in detecting this condition and the importance of differentiating KD from
tuberculosis and malignant lymphoma, the latter of which requires aggressive treatment.
10.Mastoid Abscess in Acute and Chronic Otitis Media
Mazita Ami ; Zahirrudin Zakaria ; Goh Bee See ; Asma Abdullah ; Lokman Saim
Malaysian Journal of Medical Sciences 2010;17(4):44-50
Background: Mastoid abscess remains a recognised complication of otitis media despite
the advent of antibiotics. The objectives of this study were to describe the risk factors in patients
with mastoid abscess following acute and chronic otitis media and discuss the management of this
infection.
Method: A retrospective analysis was done on all patients who underwent mastoidectomy
for mastoid abscess from January 2002 to December 2007. Data on the patients’ presentation,
associated complications, management, and follow-up were analysed.
Results: A total of 12 patients were enrolled in this study population. Group A consisted of
patients with mastoid abscess preceded by acute otitis media, while Group B consisted of patients
with mastoid abscess and chronic otitis media. In Group A (n = 7), 4 patients had a pre-morbid
immunocompromised condition, but they did not have cholesteatoma. None of the patients in Group
B (n = 5) had any pre-morbid illnesses. Out of 12 patients, 7 patients had associated extracranial
complications, and 1 patient had intracranial complications. Most patients recovered well after
mastoidectomy. Recurrence was noted in 1 patient who had acute lymphoblastic leukaemia.
Conclusion: Mastoid abscess is still a recognised complication of acute otitis media, especially
in patients who are immunocompromised. Immunocompetent patients may also develop mastoid
abscess following chronic otitis media associated with cholesteatoma. Thus, early treatment of otitis
media and close vigilant follow-up are advocated to ensure prompt detection of mastoid abscess
complications.