AIM:To compare the efficacy of intravitreal triamcino-lone acetonide and conventional treatment for macular edema in retinal vein occlusion.METHODS:In this clinical study 21 patients were enrolled with macular edema due to retinal vein occlu-sion. Prior to treatment, all patients underwent an exten-sive ophthalmic examination. Patients were divided randomly into two groups. Nine patients were treated with 4mg intravitreal triamcinolone acetonide (Kenalog) and 12 patients underwent conventional treatment.RESULTS: Before treatment, logMAR (logarithm minimum angle resolution) visual acuity in conventional treatment was 1.20±0.38 and in Kenalog group it was 1.64±0.31. One month after treatment, the visual acuity was improved to 0.98±0.54 in conventional treatment group and 0.87±0.61 in Kenalog group. There was a significant difference in visual acuity improvement between conventional treatment group and Kenalog group (0.22 vs 0.76) (P=0.01).CONCLUSION:Our results showed that although visual acuity improvement was seen in both groups but Kenalog was more effective than conventional treatment in macular edema due to retinal vein occlusion.

AIM: To evaluate Orbscan II corneal topography in hyperopic cases.METHODS: A retrospective, observational, consecutive, clinical case series in two hundred and ninety five eyes of hyperopic patients who undergo a LASIK evaluation. The information that was reviewed included age and sex of the patients and the Orbscan II corneal topographic maps. Refractive powers and the following test indices produced by Orbscan II were analyzed: keratometry, corneal diameter, pupil diameter and anterior chamber depth. RESULTS: The total mean corneal thickness was 546.3±35.5μm.It was found ; 547.3±38.4μm in 17-29 years old, 553.4±38.3μm in 30-44 years old and 546.2±29.3μm in older than 45 years old .The mean corneal thickness was found 551.5±35.9μm in female, and 542.6±34.7μm in male. The total mean depth of anterior chamber was 2.57±0.40mm and in 17-29 years old patients was 2.82±0.39mm. In 30-44 years old patients was 2.49±0.39mm and in patients older than 45 years old was 2.37±0.40mm. The mean depth of anterior chamber was 2.53±0.40mm in female and 2.60±0.40mm in male. A reverse significant relation between corneal thickness and keratometry were found. Refractive error severity had a reverse correlation with depth of anterior chamber and a correlation with keratometry (P=0.061,r=0.108).Corneal thickness had a reverse correlation with keratometry (P=0.005,r=0.160), and correlation with pupil diameter (P=0.013, r=0.144).CONCLUSION: This study provides a description and analysis of Orbscan II findings in hyperopic patients. These show mean corneal thickness 546.3±35.5μm and anterior chamber depth 2.57±0.40mm in hyperopic patients.

AIM: To describe the involvement in relatives of kera-toconus (KCN) patients with corneal topography map. METHODS: A total of 300 eyes of 150 siblings of 75 KCN patients referred to corneal clinic were studied and experienced complete slit-lamp, refraction examinations and topographic cornea maps provided by videophoto-keratography. ANOVA, Fisher exact and Chi-square tests were performed to compare the results.RESULTS: From 150 siblings, 56% were female and 44% were male with average age of 21 (range of 15-39) years old. KCN and suspect KCN diagnosed in 12.3% and 6.6% respectively. The central keratometry (CK) was 46.50±4.51 dioptr(D) in KCN and 45.66±1.52 (D) in suspect KCN. Inferior-superior value (I-S) was 3.51±2.50(D) in KCN and 1.56±1.22 (D) in suspect KCN. In KCN condition the oval pattern was 67.6% (n=25) and round pattern detected was 32.4% (n=12). In suspect KCN these patterns detected were 90% and 10% respectively. Refractive errors in KCN were -7.50 to +1.25D(-1.25±1.83), in suspect KCN 0.45 to -4.2D(-0.68±0.76) and in healthy group 2.75 to -7.5D(-0.6±1.12). Astigmatism was mild in 22.7%, moderate astigmatism in 18.3% in KCN and suspect KCN.CONCLUSION: Increase KCN condition in healthy siblings of KCN patients shows require of screening to early diagnose and cautious treatment of contact lens in these individuals.