1.The Effects of a Chinese Herbal Medicine on Gastrointestinal Disorder with Zinc Abnormality.
Fang TANG ; Hiroshi NODA ; Masao YOSHIMURA ; Michinori KUBO ; Hiroko AEB
Kampo Medicine 1995;45(4):833-839
Compared with normal mice, the concentration of serum zinc in zinc-deficient mice was significantly increased after oral administration of 1ml of 1000ppm ZnSO4 solution, while that of zinc-deficient mice treated with Kampo (Pogostemi Folium et Rhizoma, Perilla Herba, Saussureae Radix, Aurantii Nobilis Pericarpium, Anemarrhena Rhizoma, etc.) was not increased. The intestinal mucosa of zinc-deficient mice was also remarkably injured with administration of ZnSO4 but the Kampo formula inhibited its injury.
2.The Effects of a Chinese Herbal Medicine on Gastrointestinal Disorder of Mice with Zinc Abnormality. (I). The effects of Chinese herbal medicine on mice with zinc abnormality.
Fang TANG ; Yuka NAKANISHI ; Hiroshi NODA ; Machiko ORITA ; Hiroyoshi KONISHI ; Masao YOSHIMURA ; Hiroko ABE
Kampo Medicine 1994;45(2):313-321
The injury of intestinal mucosa of mice with zinc-deficiency was inhibited by the Chinese herbal medicine (_??__??_, _??__??_, _??__??_, _??__??_, _??__??_, _??__??__??_), while the concentration of serum zinc in zinc deficient mice was not increased after administrations of the Chinese herbal medicine.
3.The Effects of a Chinese Herbal Medicine on Gastrointestinal Disorder of Mice with Zinc Abnormality. (II). The effects of a Cninese herbal medicine on mice with exces zinc administration.
Fang TANG ; Yuka NAKANISHI ; Hiroshi NODA ; Machiko ORITA ; Hiroyoshi KONISHI ; Masao YOSHIMURA ; Hiroko ABE
Kampo Medicine 1994;45(2):323-330
The Chinese herbal medicine (_??__??_, _??__??_, _??__??_, _??__??_, _??__??_, _??__??__??_) suppressed the injury of intestinal mucosa in mice with excess zinc administrations. The increase of serum zinc concentration with excess zinc administrations was also inhibited by administrations of the Chinese herbal medicine.