1.Male breast cancer: The Philippine General Hospital experience.
Kristine A. Paguirigan ; Mark Richard C. Kho ; Gemma Leonora B. Uy ; Rodney B. Dofitas
Philippine Journal of Surgical Specialties 2021;76(2):35-40
RATIONALE/OBJECTIVE:
Breast cancer among males is often diagnosed
at a later age and at an advanced stage. The study aimed to present
the epidemiology, associated risk factors, clinical and pathological
characteristics, treatment patterns and outcomes of male breast cancer
patients treated at the Philippine General Hospital from January
2008- December 2017. Information from this study can provide for
better understanding of the disease and basis for creating guidelines
toward better outcomes.
METHODS:
Retrospective study of medical records involving male
breast cancer patients who underwent surgery and treatment at the
Philippine General Hospital from January 2008- December 2017.
RESULTS:
Male breast cancer accounted for 15 (0.26%) of 5,777 resected
breast specimens for breast cancer patients with a 1:384 male to female
ratio. The mean age of presentation was 60 years. The most common
presentation was a retro-areolar mass, with 33% of patients presenting
post-excision. Sixty-seven percent were at Stage II and 20% at Stage
III. About 94% of patients have invasive ductal carcinoma, while
the only other histology is papillary carcinoma at 13%. Majority of
those tested were both estrogen receptor and progesterone receptor
(ER/PR) positive (33% versus 1 %), and Her2neu negative. All
patients underwent modified radical mastectomy. Only two patients
were documented to have received adjuvant chemotherapy while
one patient received neoadjuvant chemotherapy.
CONCLUSION
Breast cancer remains to be a rare disease among males,
is often diagnosed at a later age and at an advanced stage. Because of
its rarity, awareness is necessary not only in the community but also
among healthcare providers to identify and treat the problem earlier.
Further investigation and prospective studies are recommended.
radiotherapy
;
recurrence
;
survival
2.Breast cancer in the young: A 10-year review of the diagnosis, treatment and outcomes at the Philippine General Hospital.
Sittie Aneza Camille A. Maglangit ; Arjel D. Ramirez ; Mark Richard C. Kho ; Rodney B. Dofitas
Philippine Journal of Surgical Specialties 2021;76(2):41-47
RATIONALE:
Breast cancer is the most prevalent cancer in the world.
It is usually diagnosed in women 50 years old and older, but is
also found in younger women. Its occurrence in young women
led to questions with regards issues on its tumor biology, survival
and fertility. There is insufficient local data to formulate treatment
options relevant to this age group. This study reviews the data on
breast cancer in young female patients seen in a tertiary institution.
METHODS:
This is a descriptive study involving a review of medical
records of young female breast cancer patients (<35 years of age),
seen at the Philippine General Hospital - Breast Care Center from
January 2008 to December 2017.
RESULTS:
A total of 119 patients were included in the study. Of these
young female patients, 29.4% presented with locally advanced
disease (Stage IIIB) correlating with a high number of patients who
underwent neoadjuvant chemotherapy (38.7%) and modified radical
mastectomies with primary closure (62.18%).
CONCLUSION
Breast cancer in young females should be aggressively
investigated as it commonly presents in an advanced stage.