1.An open label efficacy study of topical imiquimod 5% cream in the treatment of verruca vulgaris and verruca plana in Filipinos .
Chua Maria Angela M ; Pastorfide Georgina C ; Gonzalez Niña M ; Lim-Tiongco Jade B
Journal of the Philippine Dermatological Society 2008;17(2):44-50
BACKGROUND: Verrucae or warts, are benign epithelial growths caused by human papillomavirus (HPV) infection of the skin. They are unsightly and may affect a patient's quality of life, causing social embarrassment, discomfort, pain, and interference in certain activities.
OBJECTIVE: To evaluate the efficacy and safety of imiquimod 5 percent cream for sixteen weeks in the treatment of verruca vulgaris and verruca plana in an open-label trial involving healthy immunocompetent Filipino patients of the Dermatology out-patient clinic of the Philippine General Hospital.
METHODS: Imiquimod 5 percent cream was self-administered by patients with verruca vulgaris or verruca plana on their lesions, nightly for 16 weeks. Follow-up was done every two weeks to determine any change in size over time. Side effects were recorded.
RESULTS: Complete clearance was seen in 31.8% of verruca vulgaris cases, with improvement seen in 59 percent of cases. Shorter duration of lesions was associated with clearance. Complete clearance was seen in only 1 out of 8 patients with verruca plana treated. Minor side effects were reported.
CONCLUSION: Topical imiquimod 5 percent cream is a safe, well-tolerated, painless, convenient, patient-applied route which may be a preferred alternative treatment for verruca vulgaris.
Human ; Male ; Female ; Aged ; Middle Aged ; Adult ; Young Adult ; Adolescent ; Aminoquinolines ; Dermatology ; Hospitals, General ; Outpatients ; Pain ; Papillomavirus Infections ; Philippines ; Skin ; Warts
2.Effect of Dietary Challenges on the Flexural Properties of Resin-based Composites
Noor Azlin Yahya ; Lim Shi Yin ; Maria Angela Garcia Gonzalez
Annals of Dentistry 2021;28(1):52-60
This study aims to compare flexural strength and flexural modulus of different resin-based composites (RBCs) and to determine the impact of dietary solvents on flexural properties. Forty specimens (12x2x2mm) for each of two conventional (Aura Easy [AE]; Harmonize [HN]) and one bulk fill (Sonic Fill 2 [SF2]) were fabricated using customised plastic moulds. Specimens were light-cured, measured and randomly divided into four groups. The groups (n=10) were conditioned for 7 days at 37°C: in one of media: air (control), artificial saliva (SAGF), 0.02N citric acid and 50% ethanol–water solution. After conditioning, the specimens subjected to flexural testing. Two-way ANOVA and one-way ANOVA (post hoc: Tukey’s or Dunnett T3 tests) were used at =0.05. Significant differences in flexural properties were observed between materials and conditioning media. Flexural strength and modulus values ranged from 124.85MPa to 51.25MPa; and 6.76GPa to 4.03GPa, respectively. The highest flexural properties were obtained with conditioning in air. Exposure to aqueous solutions generally reduced flexural properties. In conclusion, the effect of dietary solvents on flexural properties were material and medium dependent. For functional longevity of restorations, patients’ alcohol intake should be considered during material selection. Dietary advice (reduce alcohol consumption) should be given to patients post operatively.
3.COLOURATION TECHNIQUES FOR INTRINSIC STAINING OF MAXILLOFACIAL SILICONE PROSTHESIS: A NARRATIVE REVIEW
PL. Ranganayakidevi S. Palaniappan ; Noor Azlin Yahya ; Maria Angela Gonzalez
Journal of University of Malaya Medical Centre 2022;25(2):122-128
Several congenital and acquired defects require alloplastic restorations. These kinds of prosthesis may be retained and supported by osseointegrated implants, the remaining skin with or without adhesive and body cavities. Extraoral maxillofacial prosthesis are primarily fabricated using silicone. Obtaining a reliable and reproducible coloration technique is important in the process of fabrication. The present study is to study the development of and advancements in intrinsic staining techniques of silicone prosthesis. The authors reviewed literature and summarized the different colouration techniques for intrinsic staining previously and presently used for maxillofacial silicone prosthesis from published research available in the Dental Library of the University of Malaya and different databases: Science Direct, PubMed and Web of Science. There are diverse methods to intrinsically match the colour of facial skin in maxillofacial prosthetics. Newer methods used in coloration have produced more accurate colour matching and have proven to be less time-consuming.
Color
4.Surface Roughness of Tooth Coloured Restorative Materials
Mohd Shahminan Ibrahim ; Yap Kai Wen ; Maria Angela Garcia Gonzalez ; Noor Azlin Yahya
Annals of Dentistry 2020;27(1):41-49
This study compared the surface roughness of selected tooth coloured restorative materials that were polished according to manufacturers’ instructions and Sof-Lex. It also assessed the surface roughness of polished materials after thermocycling. Filtek Z350XT, Beautifil-Bulk Restorative and Cention N, were used in this study. A stainless steel mould (10mm diameter x 2mm height) was used to fabricate 75 cylindrical specimens: 15 Filtek Z350XT (FZ), 30 Beautifil-Bulk Restorative (BB) and 30 Cention N (CN). All 15 FZ specimens were polished with Sof-Lex. Fifteen BB and CN specimens were polished according to manufacturers’ instructions. The remaining fifteen BB and CN specimens were polished using Sof-Lex. All the specimens were subjected to thermocycling (1000 cycles). Surface roughness was assessed quantitatively with profilometry after specimen preparation (Mylar stage), polishing and thermocycling. Data were analysed using SPSS version 25.0 at α=0.05. When polished according to manufacturers’ instructions, BB had the lowest mean surface roughness (Ra) values (0.13±0.01μm) followed sequentially by CN (0.14±0.03μm) and FZ (0.15±0.02μm). The differences were not statistically significant. When polished with Sof-Lex, BB exhibited the smoothest surface (0.116±0.03μm) followed sequentially by and FZ (0.150±0.02μm) and CN (0.157±0.02μm). Thermocycling caused an increase in the Ra. The differences were statistically significant. All materials tested had Ra values below the threshold value of 0.2 µm at Mylar stage and after polishing with their recommended polishing system and Sof-Lex. Thermocycling produced rougher surfaces that did not exceed the threshold Ra value. Polishability was material dependent.
5.The Shift of Dental Education During and Post COVID-19
Ting Jing Kweh ; Ghee Seong Lim ; Maria Angela Garcia Gonzalez ; Teng Kai Ong ; Ting Jing Kweh
Archives of Orofacial Sciences 2021;16(2):95-101
ABSTRACT
Education worldwide has been conducted in the traditional face-to-face classroom teaching style for ages,
and this includes the education in dentistry. Since the introduction of online education and distance
learning, teaching institutions have gradually made e-learning an integral part of teaching and learning
activities. With the emergence of COVID-19 pandemic and closure of teaching institutions worldwide,
the faculty of dentistry is amongst the many that were forced to leap onto the online education field
abruptly. There is a sudden need for educators to resort to online teaching and e-learning becomes an
essential tool to be developed as an alternative to traditional education methods. This article serves as a
review to explore and discuss the common concerns and institutional readiness in delivering e-learning
and review the methods currently utilised during this time of crisis.
Education, Dental
;
Education, Distance
;
COVID-19