1.Effect of tramadol on cancer pain in a patient with advanced endometrial carcinoma and myasthenia gravis: a case report
Yoshihiro Yamamoto ; Maki Todo ; Kikuyo Nishida ; Keita Iwasaki ; Chiharu Suzuki ; Miki Kondo ; Shoko Kinoshita ; Kazuyo Kanbara ; Hiromitsu Yabushita ; Akihiko Wakatsuki ; Katsuhiko Matsuura ; Mari Nishihara ; Kenichi Arai
Palliative Care Research 2013;8(2):570-574
Introduction: Tramadol (TRM) has been included as a weak opioid at the second step of the WHO analgesic ladder and has been widely used in palliative medicine. Here we report a case of amelioration of cancer pain by TRM therapy in a female patient with myasthenia gravis (MG). Case:The patient was a 70’s woman who was diagnosed with advanced endometrial carcinoma and suffered from chest pain caused by chest metastasis. 25 mg of a TRM capsule was orally administered three times a day. The dose was increased to 50 mg twice a day. It was resulted in sound pain relief with transient muscle weakness but without a myasthenic crisis.
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