Objective To explore the relevance between lymphatic metastasis and CT findings in colorectal cancer,and to estab-lish the logistic regression model to realize CT prediction for N staging in colorectal cancer.Methods Take 53 patients with complete data and colorectal cancer confirmed by pathology,and conduct correlation and regression analysis on pathological results based on the size,shape,density,edge and distribution characteristics of the regional lymph nodes that were expressed on CT images.Results It was predicted that patients with colorectal cancer showed lymph node metastasis,a number of lymph nodes with the minor axis≥ 8 mm and the irregular margin were selected in Logistic stepwise regression,the sensitivity of probabilistic model was predicted to be 85.7 %,specificity was 91.7 % and accuracy was 88.9 %;predict whether it had N2 stage,a number of lymph nodes with the heterogeneous density and the fuzzy margin were selected in Logistic stepwise regression,the sensitivity of probabilistic model was predicted to be 60.0 %,specificity 94.3 % and accuracy 86.7 %.Conclusion Lymph nodes with minor axis ≥ 8 mm,irregular margin,and heterogeneous density were the most important indicators for N staging in colorectal cancer,the combination and weigh-ting of these indicators can improve the accuracy of N staging in colorectal cancer.