Occlusal-maxillo-facial structural change of crossbite malocclusion after orthodontic therapy by modified ACTIVATOR appliance was investigated. Eighty crossbite cases of deciduous dentition and mixed dentition were treated by modified ACTIVATOR. Through pre- and post-treatment analysis of stone model, Schuller's position X-ray and craniofaciometrics, the change in craniofacial length, width and height in early-phase crossbite malocclusion was studied. The results showed that there was no significant change in the width of maxillary and mandibular dental arch. Maxillary length and protrusion was increased significantly, upper incisors slopped labially. The lower incisors slopped lingually, mental angle decreased more severely. The lower and posterior facial height was increased to normal level.
Cephalometry ; Dental Arch/anatomy & histology ; Dental Stress Analysis ; Dentition, Mixed ; Malocclusion/*therapy ; Maxilla/*anatomy & histology ; Maxilla/growth & development ; *Orthodontic Appliances, Removable ; Orthodontics, Corrective/*instrumentation ; Orthodontics, Interceptive/instrumentation ; Tooth, Deciduous

Objective:Through the design mode of Radiology and radiation protection information platform, reflects the importance of radiology information platform for public service, improve the construction speed of the practical application of horizontal, the implementation of training system and supporting platform for the construction of the subject librarian personnel. Methods:The shortcoming of the information platform, puts forward the design scheme of application of accelerating the construction of information platform and corresponding countermeasures. Results:The train subject librarians and the practical application for strong information platform, give full play to their respective functions, to ensure the nuclear emergency radiation well is very necessary. Conclusion: The construct of Radiological Medicine and protection information platform of scientific integrity, effectively play the subject librarian system, is an important guarantee to improve the nuclear accident emergency response mechanism.

OBJECTIVE To review the alteration of distribution of familiar Gram-negative bacteria of lower respiratory tract infection for patients in intensive care unit(ICU) of our hospital for reference to rational administration of clinical antibacterial drug.METHODS The 476 strains out of 736 strains collected from patients of our hospital during Jan 2003 to Dec 2006 were Gram-negative bacteria,positive ratio was 64.67%,and the features of distribution and alteration were statistically summarized.RESULTS The main germs of the 476 strains were Acinetobacter baumannii(102 strains),Pseudomonas aeruginosa(94 strains),Klebsiella pneumoniae(66 strains),Escherichia coli(54 strains),and Stenotrophomonas maltophilia(33 strains).CONCLUSIONS The main germs of pathogenic germs of lower respiratory tract infection for patients in ICU are Gram-negative bacteria,among which the isolation ratio of A.baumannii is the highest.But S.maltophilia is increasing gradually,indicating that clinical doctor should watch alteration of Gram-negative bacteria,and rationally use antibacterial drug in order to raise cure rate.

The training of clinical skills is the very important part in medical teaching.The paper is analyzing clinical skills from multiple intelligence theory and putting forward a schema about training clinical skills by micro-teaching mode.

Bortezomib (BTZ), being the first proteasome inhibitor, has been applied widely in clinic. Through combining with targeting β5 subunit/chymotrypsin-like and inhibiting the activity of proteasome reversibly, BTZ manages to inhibit intracellular degradation of protein, thus inducing apoptosis of myeloma cells. Since 2000, when BTZ was approved by Food and Drug Administration (FDA) for treatment of multiple myeloma (MM), both response rates and long-term survival time of these patients have been improved significantly. However, most patients will inevitably end up with relapse or drug resistance due to its high heterogeneity. Thus, it is of great necessity to explore the mechanism as well as overcome BTZ resistance. This review aims to summarize the current researches available on mechanisms of BTZ resistance in MM.

ObjectiveTo explore the diagnosis value of color Doppler ultrasound of the carotid atherosclerosis plaques in diabetic patients. MethodsColor Doppler ultrasonic assessment of carotid was performed in 124 diabetic patients(test group)and 100 normal controls(control group).The intima-media thickness(IMT)and the carotid atherosclerosis plaques parameters were measured.The results were compared and analyzed between two groups. ResultsThe IMT and the incidence rate of carotid atherosclerosis plaques in the test group were higher than those in the control group(all P＜0.05).There was no statistical difference in the site of the plaques between test and control group(P＞0.05). ConclusionThe incidence rate of the carotid atherosclerosis of type 2 diabetes was higher.Carotid color Doppler ultrasonography was an optimal technique for screening and diagnosing atherosclerosis.

Objective To analyse subclavian steal syndrome(SSS)by transcrinial Doppler ultrasound (TCD)and to explore the rdationship between the different degrees of subelavian artery(SUBA)and the degree of steal blood vertebral artery and clinieal value of TCD.Methods Thirty seven patients of SSS were divided into three groups according to vdoeity of SUBA and direction of vertebral artery.The stenosis of SUBA and steal degree were compared.Results Mild and moderate stenosis of SUBA were found in 15 cases with no steal and stage Ⅰ steal in 12 cases(80%);Severe stenosis of SIJBA was found in 14 cases with no steal and stage Ⅰ steal in 3 cases(21%),with significant difference between the two groups(P＜0.05).In mild and moderate stenosis group,there were 3 cases of stage Ⅱ and Ⅲ steal(20%)while in severe stenosis group there were 11 cases of stage Ⅱ and Ⅲ steal (78%),among which,the signifieant difference(P＜0.05)was observed.Stage Ⅲ steal was found in 2 cases of severe stenosis group(14%)and 7 cases of occlusion group(87%),with significant difference(P＜0.05).10 cases were found to have bilateral SUBA stenoeis,including 1 case of bilateral steal.4 cases underwent digital subtraction angiography(DSA)which results were in accordance with the results of TCD.5 cases underwent CT angiography,the results of 3 of which were similar with TCD but 2 cases did not show any abnormality.Steal happened from vertebral artery(VA)-VA in 28 cases(75.6%)and basal artery(BA)-VA in 9 cases(24.4%).Conclusion TCD could be used to diagnose SSS and the degree of steal blood.The degreo of SUBA stenosis is related to degree of vertwbral artery steal.

This paper overviewed the studies of the current situation of tongue diagnosis in psychiatric diseases (schizophrenia,depression,nervous disorders,sleep disorders and psychotropic drug-induced side-effects),summed up the importance of tongue diagnosis for the diagnosis and prognosis of mental illnesses.

Objective To explore the mutual relationship of cognitive behavioral intervention and negative emotion of leukaemia patients. Methods According to hospital dual order, 120 patients were divided into the treatment group and the control group with 60 cases in each group, the control adopted routine treatment and nursing, upon this basis, the treatment group received cognitive behavioral intervention.Anxiety and depression of two groups were compared with SAS and SDS scale. Results SAS and SDS score changed significantly in the treatment group before and after the treatment, while in the control group,the SAS, SDS score did not changed statistically. Conclusions cognitive behavioral intervention can effectively improve the anxiety and depression of leukaemia patients, and improve the quality of life and deserves further clinical promotion.

Liver transplantation rapidly has become the best choice for pediatric patients with end-stage and metabolic liver disease, since the first liver transplantation succeeded in 1989. In pediatric liver transplantation, significantly improved short-term and long-term survival is attributed to advances in surgical techniques and reasonable immunosuppression regimens in the last 20 years. However, postoperative infections, which remain the most common complication following pediatric liver transplantation, severely affect posttransplantation morbidity and mortality. This paper summarizes the infections after liver transplantation in children and rational drug use.