Juvenile idiopathic arthritis (JIA) is the most common chronic imnuro-rheumatic disease in children with different type of onset and varies clinical manifestation as well as poor prognosis.The research on the JIA have become the important subject of the connective disease.This paper has reviewed the different therapeutic methods of JIA.

This paper intends to analyze the working intention in rural areas and its influence factors of medical students .A random sampling method was used to select the sample for the study .This investigation was conducted on the medical students of grade 3 to 5 in undergraduate medical schools , junior medical colleges and technical seconda-ry medical schools from 10 western provinces .The methods of exploratory factor analysis , chi-square test , one-way ANOVA and binary logistic regression analysis were used to make the data mining .As per the results of this study , 52 .1%of the sample medical students have the working intention in rural areas .The working intention of the medical students with rural hukou (56.4%) is significantly higher than that of the medical students with urban hukou (42. 7%) .The influencing factors mainly include hukou , basic conditions of working unit , core conditions of working u-nit, gender, type of medical college, family income level, and major.In conclusion, to further expand the recruit-ment number and scope of medical students with rural hukou , and to promote the working intention in rural areas of medical students to be translated into practical working behavior , improving the core conditions of medical institutions in rural areas , and loosening and lower the recruit standards and conditions to some extent when hiring the new medi -cal workers should be viewed as some of the strategies to use .

Therapeutic hypothermia used for clinical purposes has had a long history. With the continuous development in the intensive care and surface cooling techniques, it has made various large hypothermia clinical trials possible. Studies have found that moderate hypothermia (28～35℃) has significant protective effects on important organs such as heart and brain, and it does not have obvious side effects. Recently, mild hypothermia (32～35℃) has been widely used for cardio-pulmonary-cerebral resuscitation, and its effect is satisfactory.

Objective To study the clinical effect of minocycline hydrochlorideointment on the treatment of patients with retrograde pulpitis.Methods From January 2015 to December 2016 in Huzhou central hospital, 90 cases with retrograde pulpitis as the research object were divided into two groups, the control group and the observation group, 45 cases in each group.The control group were received conventional treatment combined with iodine glycerin, and the observation group were given conventional treatment combined with minocycline hydrochloride ointment.The clinical data were compared in the two groups.Results After treatment, plaque index(0.91±0.30), gingival bleeding index(2.11±1.32), explore clinical depth(4.58±1.19)and attachment loss(3.06±1.85)in the observation group were better than the plaque index(1.38±0.49), gingival bleeding index(3.07±1.83),explore clinical depth(4.87±1.49)and attachment loss(5.18±1.39)in the control group, the difference between the two groups was statistically significant(P< 0.05);the clinical effect 95.6% in the observation group was better than 80.0% in the control group(P< 0.05).The adverse reaction rate was 6.7% in the observation group, which was lower than 17.8% in the control group(P< 0.05).Conclusion It that the conventional method combined with minocycline hydrochloride ointment on the treatment of retrograde pulpitis has significant clinical effect, can effectively improve the clinical symptoms of patients, is worthy of clinical application.

In order to investigate the medical undergraduates' clinical practice teaching method and improve teaching quality we have adopted the teaching method by taking identification and diagnosis of the disease as focal point and various informative teaching means to the practice of Grade 2001 undergraduates of our academy.We have obtained the good result by increasing students' study interest and training students' the ability of analyzing and solving the problem.

Objective To investigate the causes of development of cardiac arrest during the perioperative period in 210 hospitals of Guangxi in 2010 using a questionnaire survey.Two hundred and ten questionnaires were provided,and the valid return rate was 63.3％ (133 copies).There were 64 cases developed cardiac arrest during the perioperative period in 414,676 anesthetized patients from 133 hospitals,and the incidence of cardiac arrest was 0.0154％.Among the patients who developed cardiac arrest,the constituent ratio of the patients who were cured was 25％ (16 cases),the patients who became vegetative state was 3％ (2 cases),and the patients who died was 72％ (46 cases).Among the patients who developed cardiac arrest,the constituent ratio of general anesthesia (77％) was higher than that of intrathecal anesthesia (23％).Among the inducements for cardiac arrest,patient's factor,surgical factor,anesthesia factor,patient-surgery-anesthesia factor and unknown factor accounted for 44％ (28 cases),14％ (9 cases),25％ (16 cases),12％ (8 cases) and 5％ (3 cases),respectively.The constituent ratios of the cured patients under patient's factor,surgical factor,anesthesia factor,patientsurgery-anesthesia factor and unknown factor accounted for 13％ (2 cases),6％ (1 cases),75％ (12 cases),6％ (1 cases) and 0,respectively.The constituent ratio of the cured patients under anesthesia factor was higher than that under the other factors.In conclusion,although cardiac arrest developed during the perioperative period was rare,it endangered the patient' s life.The preoperative severity of disease was the major consideration for patient's factor,and it was not only the main inducement,but also the risk factor for death.For anesthesia factor,the main inducements causing cardiac arrest were poor airway management and circulatory depression induced by anesthetics,so preoperative airway assessment and perioperative monitoring should be strengthened.It was difficult to predict cardiac arrest induced by surgical factor or emergency events during operation,and close monitoring was the key.

0.05),PD and AL were decreased in 1 year(P

OBJECTIVE To learn the effect of performance management to enhance the proper administration of antibiotics in hospital.METHODS The performance management was applied in the proper administration of antibiotics usage.It included perfected regulation system,established the standard of the performance management,enhanced monitoring,analyzed the popular trend of drug-resistant bacteria,educated the medical staff and guided their appropriate antibiotics usage.RESULTS After taking the performance management in the administration of antibiotics,the rate of the antibiotics usage decreased from 55.1% to 44.2% and the rate of hospital infection decreased from 5.26% to 4.69%.The drug-resistant bacteria ratio obviously repressed.CONCLUSIONS Application of the performance management(a modern science management measure) in the proper administration of antibiotics usage is effective.

Nuclepore polycarbonate membrane filtration was applied for the purification of tacky-zoites in the peritoneal exudate and the saline peritoneal washing from infected mice with Toxoplasma gondii RH strain or Beverley strain. The recovery rate of tackyzoites by this method was 65. 8% and the purity of the protozoa in the filtrated suspension was as high as 98. 87%, while the protozoa in 98. 4% of the host leucocytes and 85. 2% of host erythrocytes were elimina ted respectively. The ratio of host cells to the protozoa in filtrated suspension was both lower than 1 : 100. Stain of tackyzoites with fluorescent dyes showed that more than 99% of the protozoa were alive after filtration and the re-infection of mice with the purified tackyzoites suggested that the viability, toxicity and infectivity of the tackyzoites were not affected apparently. This method was shown to be a harmless, highly efficiency, time-saving, simple, and ease method for the purification of T. gondii tackyzoites.

Objective To study the isolation and antimicrobial resistance of pathogens isolated from patients with brain damage in hyperbaric oxygenation department,so as to provide reference for clinical anti-infective treatment.Methods Bacterial culture and antimicrobial susceptibility testing results of pathogens isolated from blood,sputum,and urine specimens of 975 patients with brain damage in the hyperbaric oxygenation department of a hospital between January 2013 and December 2014 were analyzed retrospectively.Results A total of 1 328 strains of pathogens were detected,877(66.04%)of which were gram-negative bacteria,213(16.04%)were gram-positive bacteria,and 238(17.92%)were fungi.The top five isolated pathogens were Pseudomonas aeruginosa,Klebsiella pneumoniae,Escherichia coli,Acinetobacter baumannii,and Candida albicans.Specimens mainly isolated from sputum and urine,accounting for 58.59%and 35.24%respectively,resistance rates of Klebsiella pneumoniae,Pseudomonas aeruginosa,Acinetobacter baumannii,and Escherichia coli to imipenem were 16.67%,81.82%,82.44%,and 4.65%respectively.Vancomycin-resistant strains was not found among gram-positive bacteria,resistance rates of Enterococcus faecalis to most antimicrobial agents were lower than those of Enterococcus faecium.Conclusion Respiratory and urinary tract infection account for most of the infection in patients with brain damage in hyperbaric oxygenation department,gram-negative bacteria are the predominant pathogens causing infection.