OBJECTIVE To investigate the infection conditions of human papillomavirus-16(HPV-16) and-18(HPV-18) in 382 healthy women and 118 uterine cervicitis and vaginitis women.METHODS Fluorescent quantitative polymerase chain reaction(FQ-PCR) was used to detect HPV-16 and HPV-18 in 382 healthy women and 118 uterine cervicitis and vaginitis women.RESULTS In 382 healthy women,two samples were HPV-16 positive,and one sample was HPV-18 positive,with 0.52% and 0.26%,respectively.In 118 uterine cervicitis and vaginitis women,eight samples were HPV-16 positive,and three samples were HPV-18 positive,with 6.78% and 2.54%,respectively.This study made a comparison of the positive rate of HPV-16 and HPV-18 between healthy women group and uterine cervicitis and vaginitis women group.There were marked differences between these two groups(P