By first infusing large dose cold nature drugs, followed by ligating the anterior descending branch of left coronary artery and gradually narrowing down their aortic calibre, animal models were made 7-9 days after the operation, manifesting lassitude, drowsy, withered hairs, cyanotic lips and auricles, dropsy of feet. The surface temperature difference of extremities and abdomen was expanded than that of the pseudooperated animals (P