1.Severe autonomic dysfunction in a child with accidental drowning: is it a predictor for survival?
Suchismita NANDA ; Sheetal AGARWAL ; Abhinandan H.S ; Sampada KAUL ; Manju NIMESH ; Bijoy PATRA
Pediatric Emergency Medicine Journal 2025;12(2):73-77
Drowning is the third most common cause of accidental death in children. Various predictors for survival and neurological dysfunction include the age of victim, submersion time, salt versus fresh water, temperature of water, cardiopulmonary resuscitation at the scene, and time required to hospital arrival. Autonomic dysfunction, in particular heart rate variability in a critically ill patient, has been attributed to good neurological outcomes. We hereby describe a 10-year-old boy who accidentally drowned and developed a substantial heart rate variability with autonomic dysfunction. He was in the need for prolonged vasopressor support but eventually had a good neurological outcome.
2.Severe autonomic dysfunction in a child with accidental drowning: is it a predictor for survival?
Suchismita NANDA ; Sheetal AGARWAL ; Abhinandan H.S ; Sampada KAUL ; Manju NIMESH ; Bijoy PATRA
Pediatric Emergency Medicine Journal 2025;12(2):73-77
Drowning is the third most common cause of accidental death in children. Various predictors for survival and neurological dysfunction include the age of victim, submersion time, salt versus fresh water, temperature of water, cardiopulmonary resuscitation at the scene, and time required to hospital arrival. Autonomic dysfunction, in particular heart rate variability in a critically ill patient, has been attributed to good neurological outcomes. We hereby describe a 10-year-old boy who accidentally drowned and developed a substantial heart rate variability with autonomic dysfunction. He was in the need for prolonged vasopressor support but eventually had a good neurological outcome.
3.Severe autonomic dysfunction in a child with accidental drowning: is it a predictor for survival?
Suchismita NANDA ; Sheetal AGARWAL ; Abhinandan H.S ; Sampada KAUL ; Manju NIMESH ; Bijoy PATRA
Pediatric Emergency Medicine Journal 2025;12(2):73-77
Drowning is the third most common cause of accidental death in children. Various predictors for survival and neurological dysfunction include the age of victim, submersion time, salt versus fresh water, temperature of water, cardiopulmonary resuscitation at the scene, and time required to hospital arrival. Autonomic dysfunction, in particular heart rate variability in a critically ill patient, has been attributed to good neurological outcomes. We hereby describe a 10-year-old boy who accidentally drowned and developed a substantial heart rate variability with autonomic dysfunction. He was in the need for prolonged vasopressor support but eventually had a good neurological outcome.
4.Severe autonomic dysfunction in a child with accidental drowning: is it a predictor for survival?
Suchismita NANDA ; Sheetal AGARWAL ; Abhinandan H.S ; Sampada KAUL ; Manju NIMESH ; Bijoy PATRA
Pediatric Emergency Medicine Journal 2025;12(2):73-77
Drowning is the third most common cause of accidental death in children. Various predictors for survival and neurological dysfunction include the age of victim, submersion time, salt versus fresh water, temperature of water, cardiopulmonary resuscitation at the scene, and time required to hospital arrival. Autonomic dysfunction, in particular heart rate variability in a critically ill patient, has been attributed to good neurological outcomes. We hereby describe a 10-year-old boy who accidentally drowned and developed a substantial heart rate variability with autonomic dysfunction. He was in the need for prolonged vasopressor support but eventually had a good neurological outcome.
5.Severe autonomic dysfunction in a child with accidental drowning: is it a predictor for survival?
Suchismita NANDA ; Sheetal AGARWAL ; Abhinandan H.S ; Sampada KAUL ; Manju NIMESH ; Bijoy PATRA
Pediatric Emergency Medicine Journal 2025;12(2):73-77
Drowning is the third most common cause of accidental death in children. Various predictors for survival and neurological dysfunction include the age of victim, submersion time, salt versus fresh water, temperature of water, cardiopulmonary resuscitation at the scene, and time required to hospital arrival. Autonomic dysfunction, in particular heart rate variability in a critically ill patient, has been attributed to good neurological outcomes. We hereby describe a 10-year-old boy who accidentally drowned and developed a substantial heart rate variability with autonomic dysfunction. He was in the need for prolonged vasopressor support but eventually had a good neurological outcome.
6.Post COVID-19 syndrome and new onset diseases: a prospective observational study.
Nitin SINHA ; Mahinder Pal Singh CHAWLA ; Desh DEEPAK ; Amit SURI ; Piyush JAIN ; Ankit AGARWAL ; Manoj Kumar BHAKHAR
Singapore medical journal 2025;66(7):354-361
INTRODUCTION:
The National Institute of Health and Care Excellence (NICE) has defined the terms, 'acute coronavirus disease 2019' (COVID-19), 'ongoing symptomatic COVID-19' and 'post-COVID-19 syndrome', with the latter two described as having persistent symptoms after the onset of COVID-19 symptoms for 4-12 weeks and >12 weeks, respectively. Persistent symptoms can either be due to the after-effects of COVID-19 or new-onset diseases after acute COVID-19. All symptoms observed beyond 4 weeks after the onset of COVID-19 need not be present at the time of onset. Previous studies on persistent post-COVID-19 symptoms have not mentioned new-onset diseases after acute COVID-19, and only a select few studies have discussed such new-onset symptoms.
METHODS:
Ninety-five patients who attended the post-COVID-19 clinic completed the requisite follow-up till 16 weeks after COVID-19 symptom onset. Data was recorded on a predesigned proforma. Necessary investigations were conducted to rule out any other cause of persistent symptoms.
RESULTS:
Fatigue (62.1%), breathlessness (50.5%) and cough (27.4%) were the most common symptoms present beyond 4 weeks after the onset of COVID-19 symptoms. Forty-nine (51.57%) patients developed post-COVID-19 syndrome - their severity of symptoms (odds ratio [OR] 17.77) and longer duration of hospital stay (OR 1.095) during acute disease were significantly associated with the development of post-COVID-19 syndrome. During follow-up, 25 patients developed new-onset symptoms, such as diabetes mellitus, hypertension and idiopathic tachycardia.
CONCLUSION
Patients can have persistent symptoms, new-onset symptoms and new-onset diseases after recovery from acute COVID-19.
Humans
;
COVID-19/diagnosis*
;
Female
;
Male
;
Prospective Studies
;
Middle Aged
;
Adult
;
Fatigue/etiology*
;
Post-Acute COVID-19 Syndrome
;
SARS-CoV-2
;
Aged
;
Cough/etiology*
;
Dyspnea/etiology*
7.Ulnar Nerve Reconstruction With a Basilic Vein Tributary Graft: A Practical and Easily Replicable Technique With Favourable Outcomes
Collin Looi Seng Kim ; Zuhri Md Yusoff ; Manohar Arumugam ; Siew Khei Liew ; Firdati Mohamed Saaid
Malaysian Journal of Medicine and Health Sciences 2024;20(No.1):389-391
A young gentleman presented with a closed fracture of the left radius and an open fracture of the left ulna complicated with segmental loss of the ulnar nerve measuring 1.5cm. After thorough debridement and stabilization of the bone
injuries, the ulnar nerve gap was bridged with an autologous venous graft harvested off a tributary of the basilic vein
that served as a nerve conduit. At 18 months post-surgery, sensori-motor function of the patient’s left ulnar nerve was
nearly fully restored, indicative of successful reconstitution of the ulnar nerve using a basilic vein tributary vein graft.
8.Management of proximal tibial stress fracture associated with advanced knee osteoarthritis: A systematic review
Kumar Mukesh SAINI ; Mahendra SINGH ; Devendra SINGH ; Manohar Prem SEERVI ; Jayavardhan Pera REDDY ; Ramana Neelam REDDY
Chinese Journal of Traumatology 2024;27(3):147-152
Purpose::Tibial stress fracture associated with knee osteoarthritis is an unusual and difficult clinical scenario. There is no clear existing treatment guideline for this uncommon clinical disease. The aim of this study is to review the impact of various treatment options for patients with advanced knee osteoarthritis associated with proximal tibial stress fracture.Methods::The study was performed using the databases of PubMed and Scopus. Methodological index for non-randomized studies score was used to evaluate the included studies’ bias. The concluded data included the treatment approach, reported outcome measure, and time to fracture union. The literature search was started in December 2021 and accomplished in January 2022. A narrative description of the different methods and comparison of their results were done.Results::Out of total assessed 69 studies, 9 studies were included in our review. The commonest treatment approach used was total knee arthroplasty by long tibial stem extension. The mean preoperative knee society score and knee functional score were 30.62 and 23.17, respectively. The mean postoperative knee society knee score was 86.87, while the functional score was 83.52. The average reported time to achieve fracture union was 4 months (a range of 2.07 - 5.50 months).Conclusion::The optimal clinical outcome for treating either acute or mobile tibial stress fracture in patients with advanced knee osteoarthritis can be achieved with long stem total knee arthroplasty. However, due to heterogeneity of data, comparison of different treatment options for chronic proximal tibial stress fracture mal-union/non-union coexisting with knee osteoarthritic and such inferences need to be judged cautiously.
9.Autoimmune Encephalitis: Insights Into Immune-Mediated Central Nervous System Injury
Vivek PAI ; Heejun KANG ; Suradech SUTHIPHOSUWAN ; Andrew GAO ; Daniel MANDELL ; Manohar SHROFF
Korean Journal of Radiology 2024;25(9):807-823
Autoimmune encephalitis (AE) is a category of immune-mediated disorders of the central nervous system (CNS) affecting children and adults. It is characterized by the subacute onset of altered mentation, neurocognitive issues, refractory seizures/ drug-resistant epilepsy, movement disorders, and/or autonomic dysfunction. AE is mediated by autoantibodies targeting specific surface components or intracytoplasmic antigens in the CNS, leading to functional or structural alterations. Multiple triggers that induce autoimmunity have been described, which are mainly parainfectious and paraneoplastic. The imaging features of AE often overlap with each other and with other common causes of encephalitis/encephalopathy (infections and toxic-metabolic etiologies). Limbic encephalitis is the most common imaging finding shared by most of these entities. Cortical, basal ganglia, diencephalon, and brainstem involvement may also be present. Cerebellar involvement is rare and is often a part of paraneoplastic degeneration. Owing to an improved understanding of AE, their incidence and detection have increased. Hence, in an appropriate setting, a high degree of suspicion is crucial when reporting clinical MRIs to ensure prompt treatment and better patient outcomes. In this review, we discuss the pathophysiology of AE and common etiologies encountered in clinical practice.
10.Orthopaedic Specialty Committee Exit Examination Amidst the COVID-19 Pandemic in Malaysia- Experiences and Reflections from the Candidates
Firdati Mohamed Saaid ; Nur Ayuni Khirul Ashar ; Zuhri Md Yusoff ; Norazian Kamisan ; Imma Isniza Ismail ; Liew Siew Khei ; Manohar Arumugam
Malaysian Journal of Medicine and Health Sciences 2023;19(No.2):130-137
Introduction: The emergence of the COVID-19 pandemic had affected the Orthopaedic Specialty Committee (OSC)
Exit Examination candidates. The objective of this study was to evaluate the impact of this pandemic on the candidates’ teaching and learning, mental well-being, and personal experience during the examinations. Methods: A
cross-sectional study was conducted from 1st to 31st January 2021. 103 candidates for the OSC Exit Examination
November 2020 were asked to answer a questionnaire. Wilcoxon signed-rank tests were used to compare differences in the frequencies before and during the pandemic. A p-value of less than 0.05 was taken as significant. Results:
There was a significant reduction in the number of classes (P-value < 0.001) and examination preparatory courses
conducted, reduced number and variety of patients attended and limited exposure in the operation theatre. Most
candidates had virtual and physical classes, and agreed virtual clinical teaching was less effective. A majority had
increased caffeine intake and smoking habits, decreased time spent with family and sports activities and no impact
on sleeping hours, alcohol and analgesic usage. During the examinations, most candidates felt disturbed by the
COVID-19 safety protocol and worried about the risk of contracting the infections. Conclusion: The effect of this pandemic on the post-graduate Orthopaedics students teaching and learning is massive. Virtual teaching programmes
or applications that can replace the traditional clinical teaching methods should be explored and developed for the
benefit of our education system.


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