Objective To exploit the best therapy of medical abortion during the gestation period from12 to 24 weeks. Methods The therapy of the observatory group included: Diethylstilbestrol, Mifepristone and Misoprostol. And that of the control group was: Mifepristone and Misoprostol. Results The effective rate of observatory group was 100%, the uterus contracted in (0.57?0.24)hours , the placenta and fetus were delivered in(7.22?4.91)hours, the volume of blood lost during labor was (148.99?58.94)ml, clearance lochia time was (14.8?7.8)days. The effective rate of control group was 92%, and uterus contracted in (0.63?0.37)hours, the placenta and fetus were delivered in(9.21?1.96)hours, the volume of blood lost was (148.99?58.94) ml, clearance time lochia is (18.6?9.0)days. According to the above datum, the two groups showed significant difference ( P

Objective To observe the effect of different doses of sufentanil on intubation guided by fiber bronchoscope in diffi‐cult airways .Methods One hundred and eighteen patients with difficult airways who underwent tracheal intubation were randomly divided into 3 groups [groupⅠ(n=40) ,groupⅡ (n=42) ,and groupⅢ (n=36)] .First all group received 1 μg/kg dexmedetomi‐dine ,then groupⅠ ,groupⅡ and group Ⅲ received sufentanil 0 .1μg/kg ,0 .2 μg/kg ,0 .3μg/kg infusion in bolus respectively .Heart rate(HR) ,mean arterial pressure(MAP)and saturation of pulse oximetry(SpO2 )were recorded at 5 min after patients arriving at operation room (T0 ) ,after drug infusion(T1 ) ,the time of intubation and seeing the epiglottis (T2 ) ,1 min(T3 )and 5 min(T4 )after intubation .side effect was recorded throughout the process .Results HR at T2 and T3 in groupⅡ and group Ⅲ were significantly lower than those in group Ⅰ(P<0 .05) .MAP at T2 and T3 in groupⅡ and group Ⅲ were significantly lower than those in groupⅠ(P<0 .05) .SpO2 at T2 in group Ⅲ was significantly lower than those of groupⅠ and groupⅡ(P<0 .05) .Cough reflex in groupⅠwas much frequent than others .Only group Ⅲ had respiratory inhibition .Conclusion Intravenous sufentanil (0 .2 μg/kg)could in‐hibit effectively stress reaction from endotracheal intubation ,in which less side effects such as haemodynamic changes and respirato‐ry depression occur .

Objective To investigate the causes, clinical features, classifications and liver function change of drug-induced liver damage (DILD) in the elderly. Methods One hundred and sixty seven inpatients with acute drug-induced liver injury in our hospital in the past ten years (January 2000 to December 2009) were retrospectively investigated,and the diagnosis and classification methods of acute DILD were based on international consensus meeting (international criteria). Results Among 167 DILI cases, there were 53 cases (31.7%) in the older group and 114 cases (68.3%) in middle-youth age group. Fatigue and jaundice were the more common symptoms, accounting for 50.3% and 46.7%, respectively. In 167 cases, no obvious symptoms and signs were shown in 25 cases. There were no significance differences in clinical manifestation between two groups. Many drugs could induce liver injury. The most common drugs inducing DILD were Chinese traditional and herbal drugs, accounting for 47.9%. Drugs used in heart diseases and inducing liver injury were more common in the older group. In this study, 40 (75.5%), 5 (9.4%) and 8 (15.1%) cases were designated as hepatocellular, cholestetic and mixed DILD in the older group, and 91 (78.9%), 8 (7.4%) and 15 (13.7%) in middle-youth age group, respectively. There were no significance differences between two groups in classifications. Conclusions Many drugs could cause liver injury. The symptoms of acute DILD are nonspecific. Drugs used in heart diseases and inducing liver injury are more common in older patients.

Objective An 80 years old man,suffered from cardiopulmonary arrest during swimming.After successfully cardiopulmonary resuscitation,he was sent to a hospital.After examination and inspection,he was diagnosed as cardiopulmonary arrest,aspiration pneumonia,hyperlipidemia,high level of creatine kinase.We prescribed a statin for the hyperlipidemia,but the level of creatine kinase was higher and higher.Finally he was diagnosed as hypothyroidism and lung cancer.We considered that severe weakness may be the reason of cardiopulmonary arrest in swimming pool.

OBJECTIVE: To explore the therapeutic effects of endoscopic sinus surgery on symptoms and quality of life of patients with chronic rhino-sinusitis (CRS). METHODS: A survey of symptoms and quality of life was conducted using Sino-nasal Outcome Test-20 (SNOT-20) questionnaire with 76 patients before and after endoscopic sinus surgery. The overall effect of endoscopic sinus surgery on CRS was subjectively self-evaluated by patient. RESULTS: After 6 months following-up, the total SNOT-20 score of patients was significantly decreased from the baseline (P<0.001). The most important 5-items were found to be "thick nasal discharge", "need to blow nose", "dizziness", "frontal pain", and "lack of a good sleep". Other items, related to sleep and emotion, were also significantly improved: the proportion of responses of "much improved", "improved" and "no-improved" were 56.3%, 33.3%, 10.4%, respectively. CONCLUSION Endoscopic sinus surgery demonstrated positive effects on symptoms and quality of life of CRS patients.
Adolescent ; Adult ; Aged ; Chronic Disease ; Endoscopy ; methods ; Female ; Humans ; Male ; Middle Aged ; Nasal Polyps ; complications ; surgery ; Quality of Life ; Sinusitis ; complications ; surgery ; Surveys and Questionnaires ; Treatment Outcome ; Young Adult