1.Prevention of Homologous Blood Transfusion by Intraoperative Predonation on Valvular Surgery without Preoperative Autologous Donation
Koichi Sato ; Masakazu Sogawa ; Osamu Namura ; Chizuo Kikuchi ; Manabu Isoda ; Junzo Watanabe ; Takeshi Okamoto ; Takehito Mishima ; Jun-ichi Hayashi
Japanese Journal of Cardiovascular Surgery 2006;35(1):1-4
Though preoperative autologous donation is not acceptable for all cases partly because some are preoperatively in a severe condition, intraoperative predonation is possible in almost all cases. We retrospectively evaluated the major factors related to the prevention of homologous blood transfusion by intraoperative predonation in 25 cases following valvular surgery without preoperative autologous donation. Homologous blood was not transfused in 18 cases {Group-(-)} but in 7 cases only after CPB {Group-(+)}. The male/female ratio, type of operation, body weight, CPB dilution, CPB duration, and perioperative change in hematocrit were comparable in the 2 groups. However, the autologous blood pooled before CPB in Group-(-) was significantly more than in Group-(+) (11.3±2.5 vs 7.3±1.8ml/kg, p<0.001). In conclusion, homologous blood transfusion may be prevented by appropriate intraoperative predonation during surgery for valvular disease.
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