A movable television camera for observing operations was constructed. The camera is attached to the end of a long, extendable arm that is supported by a column. The column stands on a wheeled cart. A television monitor is also placed on the cart. With this television camera, medical students can observe any operation, even if the surgical field is deep and narrow, in any operating room.

The effect of moxibustion on the endocrinosis elicited by disorders of the autonomic nervous system was investigated in hypophysectomized rat.
Natural gain of body weight was stopped, adrenals and testis became atrophied, urinary output increased, and the rectal temperature slightly dropped after hypophysectomy.
Applying moxibustion did not correct these synptoms.
Furthermore, in spite of electrolyte and amino acid metabolism, significant decrease of Na, K, Cl, Ca and a slight decrease of urea nitrogen and creatinine in urine was recognized. But these were not modify by moxibustion.
With respect to the adrenal cortical study, there were a slight increase of 17-OHCS and a mild decrease of 17-KS in urine. Moxibustion did not effect either 17-OHCS or 17-KS.

The purpose of this study was the evaluation of the relationship between the degree of obesity (relative body weight ratio) and values of various components in blood. The degree of lean and obesity was defined as the ratio of actual body weight to standard body weight calculated by the method of katsura. Mean ± standard error and percent frequency of abnormal values of blood components were studied in 880 women with degree of lean and obesity from 80 to 170 % among the women in agricultural villages. The class mean in subjects with relative body weight ratio between 100 and 109 % was used as the standard class value for comparison with these values. The following results were obtained.
1, Red blood count, hemoglobin and hematocrit values were significantly increased as the degree of obesity reached 130-140 %, compared to the standard class value, along with a significant fall of % frequency.
2. Behavior of serum components with reference to the degree of obesity showed a marked component to component variation. The mean level of SGOT, SGPT, γ-GTP, TRIG, CHOL and UA rose along with the increase of the degree of obesity from the lean range via the standard body weight range to the obesity range. ALP, however, was high in the obese and lean ranges, and low in the standard body weight range. BUN showed a tendency in reverse. Electrolyte and creatinine values were not remarkably different between lean and obese persons.
3. Marked changes of the mean levels were seen along with obesity in SGOT, SGPT, γ-GTP, cholesterol and triglyceride. Many of these showed significant increase of the mean in subjects with degree of obesity between 120 and 129 % compared to the standard class value. In subjects with degree of obesity of 140-149 %, frequency of abnormal values were significantly elevated. These results would suggest on an epidemiological basis that detailed examinations of the functional abnormalities of organs and environment in vivo thorugh blood testing is necessary for health control in subjects with degree of obesity of more than 140 % by Katsura method.

Objectives : In Wechsler Intelligence Scale for Children-Fourth Edition (WISC-IV), full scale intelligence quotient (FSIQ) and the index scores are thought to be solely important and supplemental subtests are not taken into account in the score.However, in assessment by intelligent tests it is required that we analyze the result from many directions. Accordingly, the factor of “Cancellation” was taken up and the importance of adding a focus on the qualitative side of the test results was examined. Methods : Some 412 children who received WISC-IV in our developmental evaluation center were divided into three groups according to their intellectual level, and of these, 30 persons were assigned to each group [total of 90] selected at random to comprise the sample. By comparing the index scores and the scaled scores for each group,we have classified the procedures of deletion into six types. Results : The more the intellectual level increases, the lower the “Cancellation” scaled score becomes compared to the other subtests. Further, the scaled score was lower in the type of deletion procedure such as systematic linear strategy. Conclusion : In the high intellect level group, the scaled “Cancellation” score was lower than the other subtests, it was thought to be because there were many “order type” subjects using a systematic linear strategy. It was also considered that attention to the qualitative aspects as well as quantitative is important in “Cancellation”. Therefore, when assessing high intellect children with developmental disabilities in the future, a clinical examination that incorporates “Cancellation” to detect executive function disabilities such as persistence or poor planning ability is desirable.

We performed combination therapy with modified oxaliplatin/l-LV/5-FU (mFOLFOX) in a patient with recurrent colorectal cancer who had peritonitis carcinomatosis. In this patient, mFOLFOX therapy resulted in disappearance of ascites and a decrease in carbohydrate antigen 19-9 (CA19-9), and improved quality of life (QOL) of the patient. This 62-year-old man was diagnosed with ascending colon cancer and metastatic cancer of the liver. Right hemicolectomy and right hepatic lobectomy were performed. We had started to treat with TS-1 in ambulatory care, however, he had peritonitis carcinomatosis with massive ascite reservoir on CT and peritoneal dissemination after a half year postoperatively. Furthermore, his ECOG Performance Status (PS) was rated as level 3. Therefore, we performed puncture of ascites and palliative mFOLFOX6 therapy. After ten courses, ascites and abdominal induration had disappeared and PS recovered to level 1. At present, CPT-11/l-LV/5-FU (FOLFIRI) are being administered for peripheral neuropathy and metastatic tumor associated with mFOLFOX6. The patient is spending his daily life satisfactory after FOLFIRI without abdominal swelling or ascites, and thus mFOLFOX6 may be an option for palliative therapy against massive ascites in patients with advanced colorectal cancer. The usefulness of palliative mFOLFOX6 therapy for patients with massive ascites should be evaluated in a well-designed clinical trial.Palliat Care Res 2008; 3(2): 316-320

A woman in her 60s was being treated for diabetes and hypertension but had impaired activities of daily living (ADL) due to severe obesity (150 kg). She was transported to the emergency department because of disturbance of consciousness in August 201X. Imaging findings showed decreased permeability of the whole right lung field. She was intubated and started on ceftriaxone plus levofloxacin for severe infection with respiratory failure. Erysipelothrix rhusiopathiae was detected in blood cultures, leading to a diagnosis of sepsis due to a large pressure ulcer on the posterior aspect of the thigh. We switched levofloxacin to clindamycin and continued medical treatment, and she was extubated on the 10th day of illness. However, type 2 respiratory failure was prolonged because of alveolar hypoventilation due to obesity and she required noninvasive positive pressure ventilation. Also, she had difficulty getting out of bed due to obesity, disuse syndrome, and pressure ulcer. Cooperation among staff from many professions, including respiratory nursing, intensive care nursing, wound, ostomy and continence nursing, physical therapy, and nutrition management, led to improvement of ADL and weight loss (to 109 kg), allowing her to be transferred out of the intensive care unit.

Objective: Monitoring the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants is important due to concerns regarding infectivity, transmissibility, immune evasion and disease severity. We evaluated the temporal and regional replacement of previous SARS-CoV-2 variants by the emergent strains, Alpha and Delta. Methods: We obtained the results of polymerase chain reaction screening tests for variants conducted in multiple commercial laboratories. Assuming that all previous strains would be replaced by one variant, the new variant detection rate was estimated by fitting a logistic growth model. We estimated the transmission advantage of each new variant over the pre-existing virus strains. Results: The variant with the N501Y mutation was first identified in the Kinki region in early February 2021, and by early May, it had replaced more than 90% of the previous strains. The variant with the L452R mutation was first detected in the Kanto-Koshin region in mid-May, and by early August, it comprised more than 90% of the circulating strains. Compared with pre-existing strains, the variant with the N501Y mutation showed transmission advantages of 48.2% and 40.3% in the Kanto-Koshin and Kinki regions, respectively, while the variant with the L452R mutation showed transmission advantages of 60.1% and 71.9%, respectively. Discussion In Japan, Alpha and Delta variants displayed regional differences in the replacement timing and their relative transmission advantages. Our method is efficient in monitoring and estimating changes in the proportion of variant strains in a timely manner in each region.