1.Allometry theory to create a standard value for bone mineral content for menstruating adult females and examination of usefulness
Mami Yanagawa ; Yoshiyasu Higuchi ; Takeshi Matsubara ; Makoto Numata ; Kiyoshi Taneda ; Yumiko Sakai ; George Koike ; Munehiro Shindo
Japanese Journal of Physical Fitness and Sports Medicine 2014;63(2):259-267
Evidence suggests that sports activity can induce site-specific changes in bone mineral content (BMC) in athletes. Therefore, the first purpose of this study was to create a standard value for BMC (SVBMC) that is independent of body size and physical exercise effect. The second purpose was to examine usefulness for the SVBMC. In creating the SVBMC, we recruited non-customer subjects who engaged in regular exercise but did not have site-specific changes to their bony structure. We studied 285 females (34.0±6.5 years) that were currently active, free from hormone treatment, and were not taking medication for any condition. Furthermore, all female subjects reported having a normal menstrual cycle. Bone area (BA), BMC and areal bone mineral density (aBMD) were measured by dual-energy X-ray absorption. Measurements of almost the complete skeleton, with the exception of the head, were taken (herein referred to as sub-total). This included scans of the entire spinal column, all 12 ribs, pelvis, full legs and arms. An allometry formula that relates BMC and BA was applied to determine the SVBMC. To exclude the effect of body size, calculations were determined using the perpendicular distance from the data of each individual to that determined by allometry regression. Finally, the mean and standard deviation of the distance were converted into T-scores. In examination of reliability for the SVBMC, we calculated the SVBMC for three customer females who engaged in regular exercise. We found a significantly positive relationship between SVBMC and weight/BMI. This correlation was weaker than the relationship between SVBMC and BMC, as expected, or the relationship between SVBMC and aBMD, with the exception of SVBMC in the pelvis. In conclusion, this study suggests that SVBMC is less affected by body size than by BMC or aBMD and the SVBMC was provided highly useful in case study.
2.The effect of bench-stepping exercise training on BMD, BMC and bone metabolism in menopausal women
Takeshi Matsubara ; Yumiko Sakai ; Mami Yanagawa ; Chiga Hijii ; Makoto Numata ; Kaoru Egami ; Yasuko Yamaguchi ; Yuko Mine ; Toru Maeda ; Hiroaki Tanaka ; Munehiro Shindo ; George Koike
Japanese Journal of Physical Fitness and Sports Medicine 2013;62(1):95-103
Since the effect of the submaximal aerobic exercise on bone had been controversial, the aim of this study was to elucidate the effect of the bench step (BS), that seemed to deliver higher mechanical load on bone than any other aerobic exercises, on the total bone mineral content (BMC) and the bone metabolism of menopausal women. Sixteen menopausal women (65 ± 9 years old) as the exercise group (ExG) and 28 pre-menopausal women (43 ± 3 years old) as the control group (CG) were studied. ExG carried out BS training with the exercise intensity at lactate threshold (LT) for 21 weeks. In ExG, BMC was measured by dual energy X-ray absorptiometry (DXA) at one year before the intervention (A year before), pre-intervention (Pre) and post-intervention (Post). Serum osteocalcin (OC) as the marker of bone formation and serum type I collagen cross-linked N-telopeptide (NTx) as the marker of bone absorption at Pre, 11th week of the intervention and Post. In CG, BMC was measured annually without the intervention. In ExG, OC was not changed, but NTx was significantly decreased by intervention (p<0.05). The decreased amount of annual change in BMC between a year before and Pre (T1) was significantly higher compared to that between Pre and Post (T2) (p<0.01) and CG (p<0.001). There was no significant difference between T2 and CG. In conclusion, BS with LT could prevent decreasing BMC in menopausal women, and maintain the same level of BMC in pre-menopausal women by suppressing the bone absorption.
3.Effect on Undergraduate Medical Students of Exposure to a Summer Camp for Children with Asthma.
Shigemi YOSHIHARA ; Toshio ABE ; Yumi YAMADA ; Makoto WATANABE ; Mika ONO ; Mariko OYAMA ; Sanae KANAZAWA ; Michio NUMATA ; Kiyoshi NISHIKURA ; Daisuke NAKAJIMA ; Megumi HOSHI ; Norimasa FUKUDA ; Tamotsu ANDO ; Noriko KANNO ; Osamu ARISAKA ; Mitsuoki EGUCHI
Medical Education 2001;32(1):39-45
We investigated the effects on medical education of early exposure of undergraduate students to a summer camp for children with asthma. An objective evaluation by the editorial staff found final improvements in the following areas (in descending order of frequency): learning of basic medical behavior (91% of students); cooperative attitude of medical staff in general treatment with the patient and the patient's family (88%); understanding of childhood growth and development (80%); knowledge of childhood asthma (69%); and mastery of basic techniques for therapy and examination (41%). The differences in the ratio of improvement (%) before and after visiting the camp, were (in descending order of frequency): cooperative attitude of medical care staff in general medical treatment with the patient and the patient's family (47%); understanding of childhood growth and development (45%); knowledge of childhood asthma (38%); learning of basic medical manner (34%); and mastery of basic techniques for therapy and examination (25%). These findings suggest that a summer camp is useful for exposing undergraduate medical students to children with asthma and is effective for helping them understand patients and family-oriented pediatric medicine.