Objective To investigate the conrelation between neutrophils lymphocytes ratio (NLR) and disease activity of ulcerative colitis (UC).Methods Case-control study was used to compare NLR differences of 82 active UC patients,45 inactive UC patients,and 254 healthy controls.The multivariate analysis was applied to analyze the correlation between the NLR,erythrocyte sedimentation rate (ESR),Creactive protein (CRP),white blood cells (WBCs),and UC activity.The sensitivity and specificity of NLR to identify UC activity was evaluated.Results NLR of active UC group was 2.45 ± 1.22,which was significantly higher than that of inactive UC group and healthy control group,their NLR were 1.92 ± 0.68 and 1.83 ±0.75,respectively (H =9.991,P =0.007).The multivariate analysis showed that only CRP was correlated with UC activity (OR =1.396,95％ CI:1.086 ～ 1.795,P =0.009).Receiver operating characteristic (ROC) curve analysis showed that the optimum NLR cut-off point for UC activity was 2.23,the sensitivity and specificity were 55.82％ and 62.75％,respectively.Conclusions NLR has a certain reference value for the evaluation of UC activity,but it cannot be independent as a clinical index to evaluate the UC activity.

Objective: To study the effects of a standardized diagnosis and treatment program for type 2 diabetes mellitus patients, in a community in Urumqi. Methods: In March 2016, 1 000 patients with type 2 diabetes at the Urumqi Xinhua Road community health service center and affiliated communities were selected to participate in a questionnaire survey and in a promotion for a 12-month standardized treatment. T-test and χ² test were used to compare the blood sugar, blood pressure, blood lipids, ratio of urine microalbumin and creatinine (urine A/C) and other metabolic indices in patients before and after the promotion. Results: In a total of 112 finalists, after a 4-month follow-up, rates of regular exercise, diet control, taking medication on time and regular blood glucose monitoring all improved significantly from 35.7%, 40.2%, 13.7%, 29.5% to 56.3%, 68.8%, 56.3%, 45.5%, respectively (χ²=9.508, 8.643, 45.319, 6.171; P < 0.05). The rates of smoking and drinking were lower after the promotion (χ²=4.291, 4.56; P < 0.05). Body mass index (BMI), fasting blood glucose (FPG), glycated hemoglobin (HbA1c), systolic blood pressure, total cholesterol (TC), creatinine, and urine A/C decreased significantly, while there was no significant difference in the diastolic blood pressure. The percentage of participants with normal blood sugar, lipids and blood pressure, significantly improved from 38.4%, 37.5%, 23.6%, 8.9% to 63.4%, 66.4%, 43.7%, 23.2%, respectively. The rate of urine A/C positivity decreased from 40.2% to 26.8% (χ²=14.004, 18.309, 10.604, 8.473, 4.510, P < 0.05). Conclusion Standardized type 2 diabetes treatment programs can improve the blood levels of glucose and lipids, as well as lower blood pressure and the positive rate of urine A/C. It can help reduce the multiple risk factors and long-term complications by improving the self-management of diabetes.