1.Studies on chemical constituents of Bletilla striata Ⅱ
Guangxuan HAN ; Lixin WANG ; Weidong ZHANG ; Maili WANG ; Hongtao LIU ; Jianhu XIAO
Academic Journal of Second Military Medical University 2001;0(09):-
Objective:To study the polar chemical constituents of Blettila striata(Thunb.) Reichb.f. Methods:The constituents in N-butanol moiety were separated and purified by column chromatography with silica gel and SephadexLH-20, and were identified by spectral analysis. Results:Five compounds were identified as: militarine(1);7-hydroxy-4-methoxy-phenanthrene-2-O-?-D-glucoside(2);4-methoxyphenanthrene-2,7-O-?-D-diglucoside(3);7-hydroxy-2,4-dimethoxyphenanthrene-3-O-glucoside(4);3′-hydroxy-5-methoxybibenzyl-3-O-?-glucopyranoside(5). Conclusion:Compound 1,5 were isolated from this plant for the first time.
2.Effect of Yinaotongluo Capsule on diffuse weighting image and energy metabolism of ischemia-reperfused rats
Meikui ZHANG ; Maili LIU ; Ling YIN ; Xuesong WANG ; Xu ZHANG ; Yigen WU ; Bin YAO ; Xianglan JIN
Chinese Journal of Rehabilitation Theory and Practice 2005;11(7):507-508
ObjectiveTo explore the effect of Yinaotongluo Capsule on diffuse weighting image and enenery metabolism of ischemia-reperfuing rat.MethodsMagnetic resonance diffusion-weighted imaging(DWI) and 1H and magnetic resonance spectroscopy(MRS) were performed in different brain regions in focal cerebral ischemic-reperfusion injury model rats. ResultsYinaotongluo Capsule could significantly reduce the area and the intensity of infarction of rats by DWI 3 h and 5 d after treatment compared with the model group.The result of 1H MRS examination demonstrated Lac peak was lower and NAA peak higher than that of the model group. ConclusionYinaotongluo Capsule can effectually improve enenery metabolism during cerebral ischemia and reperfuing, so that to reduce the neuronal dysfunction and death in infarcts at the late stage.