1.Platelet Lymphocyte Ratio (PLR) as a predictor of in-hospital outcomes among Acute Ischemic Stroke (AIS) patients in a tertiary hospital
Frances Eunice B. Alcober ; Joyce Matoza-Serna ; Maidy Ann V. Arguelles
Philippine Journal of Neurology 2024;27(1):28-36
Introduction:
Acute Ischemic Stroke (AIS) is a medical emergency that affects people globally. In the
Philippines, it remains as the third leading cause of mortality. This study aims to determine the
use of platelet-lymphocyte ratio (PLR) - a simple, economical, and safe tool - as a predictor of
in-hospital outcomes in patients with acute ischemic stroke.
Methods:
A retrospective cross-sectional study was conducted among AIS patients at the Remedios
Trinidad Romualdez Hospital (RTRH) Tacloban City, Leyte, Philippines from January 2020 to
December 2022. Clinical demographics, laboratory profile, and hospital outcomes were
described. Descriptive statistics, Mann-Whitney test, and T-test were utilized to determine the
association between PLR and in-hospital outcomes.
Results and Conclusions
There were 76 patients enrolled in the study, majority were females (57.9%), and hypertensive
(84.2%). Risk factors that are pivotal to the development of AIS were also identified. To note,
half of the population presented with unilateral body weakness. Moreover, only 7.9% died due
to the disease. Higher PLR levels resulted from an increased platelet count and a decreased
lymphocyte count. However, no significant association between PLR levels and AIS outcomes
was noted, hence the need for further investigation of these parameters.
Ischemic Stroke
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Tertiary Care Centers