1.Cardiovascular-obstetric state-of-the-art review: pulmonary hypertension in pregnancy.
Joy Yi Shan ONG ; Jeannie Jing Yi YAP ; Mahesh CHOOLANI ; Kian-Keong POH ; Pradip DASHRAATH ; Ting-Ting LOW
Singapore medical journal 2025;66(3):130-140
Pulmonary hypertension in pregnancy has been associated with negative maternal and fetal outcomes over the past decades. With the emergence of novel treatment modalities, morbidity and mortality of women who have pulmonary hypertension in pregnancy have improved. In this review, we aim to explore the contemporary updates in the management of pre-capillary and post-capillary pulmonary hypertension in pregnancy.
Humans
;
Pregnancy
;
Female
;
Hypertension, Pulmonary/physiopathology*
;
Pregnancy Complications, Cardiovascular/diagnosis*
;
Pregnancy Outcome
;
Antihypertensive Agents/therapeutic use*
4.Navigating health challenges: Singapore's National University Health System's approach to child and family well-being.
Yee Keow CHIONG ; Wanyun LIN ; Logan MANIKAM ; Wei Ying HAI ; Mat SHAH ; Jeannie CHIAM ; Mahesh CHOOLANI ; Yung Seng LEE
Annals of the Academy of Medicine, Singapore 2025;54(2):138-141
8.Genetics in prenatal diagnosis.
Karen Mei Xian LIM ; Aniza Puteri MAHYUDDIN ; Arundhati Tushar GOSAVI ; Mahesh CHOOLANI
Singapore medical journal 2023;64(1):27-36
The options for prenatal genetic testing have evolved rapidly in the past decade, and advances in sequencing technology now allow genetic diagnoses to be made down to the single-base-pair level, even before the birth of the child. This offers women the opportunity to obtain information regarding the foetus, thereby empowering them to make informed decisions about their pregnancy. As genetic testing becomes increasingly available to women, clinician knowledge and awareness of the options available to women is of great importance. Additionally, comprehensive pretest and posttest genetic counselling about the advantages, pitfalls and limitations of genetic testing should be provided to all women. This review article aims to cover the range of genetic tests currently available in prenatal screening and diagnosis, their current applications and limitations in clinical practice as well as what the future holds for prenatal genetics.
Child
;
Pregnancy
;
Female
;
Humans
;
Prenatal Diagnosis
;
Knowledge
;
Parturition
9.Singapore Medical Journal: reflecting on 2023.
Tiing Leong ANG ; Mahesh CHOOLANI ; Kian Keong POH
Singapore medical journal 2023;64(12):713-713
10.Resilience amidst winds of change.
Tiing Leong ANG ; Mahesh CHOOLANI ; Kian Keong POH
Singapore medical journal 2022;63(1):1-1

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