1.Discoid lupus erythematosus degenerating to squamous cell carcinoma.
Yudha Selviyanti P. ; Abad-Venida Ma. Luisa
Journal of the Philippine Dermatological Society 2008;17(2):74-76
A 40-year-old male presented with multiple erythematous scaly plaques over the right cheek, lips, left preauricular area, 'v' neck areas, the upper extremities, and a large fungating flesh colored tumor on the nasal bridge extending to right eyelid and malar area. Histologically, the plaque lesions were consistent with discoid lupus erythematosus (DLE), and the fungating growth with squamous cell carcinoma (SCC).
Human ; Male ; Adult ; Carcinoma, Squamous Cell ; Cheek ; Lip ; Lupus Erythematosus, Discoid ; Neck ; Skin
2.A case of a 62-year-old male with Actinomycetoma successfully treated using combined medical and surgical therapy.
Arbie Sofia P. Merilleno ; Abelaine Venida-Tablizo ; Ma. Luisa Abad-Venida
Journal of the Philippine Medical Association 2023;101(2):45-48
INTRODUCTION:
Actinomycetoma is a neglected infectious
disease that presents with a triad of subcutaneous mass,
with sinus formation and seropurulent discharge
containing grains. This causes severe functional disability
to patients if not treated early and properly.
CASE REPORT:
We report a case of a 62-year-old adult
Filipino farmer diagnosed with actinomycetoma of the left
foot. For 8 years, the patient medicated with several
antibiotic therapies affording minimal improvement of
symptoms. Hence, surgical intervention with combination
antimicrobial therapy was done which provided resolution
of symptoms, improving the quality of life of the patient.
CONCLUSION
Treatment of actinomycetoma must be
individualized among patients. Although oral antibiotics
became the standard of treatment, combining surgical
treatment with oral medications may be considered to
ensure effective management of the disease.
actinomycetoma
;
cotrimoxazole
;
dapsone
;
surgery
;
case report
3.Large basal cell carcinoma in a 101-year-old Filipino female: A case report
Jianella Catrisse D. Diaz ; Daisy King-Ismael ; Ma. Luisa Abad-Venida ; Zharlah Gulmatico-Flores
Journal of the Philippine Dermatological Society 2021;30(2):61-64
Introduction:
Basal cell carcinoma (BCC) is the most common type of malignancy worldwide. The incidence of BCC is positively
associated with increasing age; thus, centenarians, defined as those aged 100 years and above, become a vulnerable population
to developing malignancy. As a person ages, risk factors such as chronic sun exposure, ionizing radiation, and immunosuppres-
sion induce mutations that contribute to tumor formation. Impaired DNA repair capacity in response to carcinogens and immune
function dysfunction also increases BCC risk in the elderly. Currently, studies among centenarians with high-risk basal cell car-
cinoma treated with surgical interventions are limited.
Case report:
Presented herewith is a case of a 101-year-old female with a 15-year history of hyperpigmented, hyperkeratotic
plaque over the right malar area and a one-year history of progressive pain (PS 10/10) and enlargement of the lesion, forming an
ulcerated, hyperpigmented tumor. Laboratory workup showed normal findings. Histopathology was signed out as a pigmented
nodulocystic basal cell carcinoma. Moh’s micrographic surgery (MMS) and cheek advancement flap were performed with good
wound healing and no perioperative complications.
Conclusion
Despite the limited options of medical and physical management due to decreased life expectancy of centenar-
ians, MMS remains the standard of therapy in high-risk BCC. MMS with reconstructive surgery is generally a safe and effective
modality with no increased risk of peri- and post-operative complications.
Carcinoma, Basal Cell
;
Centenarians